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pro vyhledávání: '"C. Randall Moss"'
Autor:
Joseph S. Pagano, C. Randall Moss, Wyatt T. Cramblet, Leslie Hilding, Emma K. Fath, Julia Shackelford, Sadia Salahuddin, Matthew Varn, Natalie Biel, Tabithia Ross, Ashley Ray, Akash Patel, Gretchen L. Bentz, Sheetal Patel, Angela J. Lowrey
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Epstein-Barr Virus latent membrane protein-1 (LMP1) interacts with the SUMO-conjugating enzyme Ubc9, which induces protein sumoylation and may contribute to LMP1-mediated oncogenesis. After analyzing human lymphoma tissues and EBV-positive cell lines
Autor:
C. Randall Moss, Gretchen L. Bentz, Leslie Hilding, Angela J. Lowrey, Natalie Biel, Matthew Varn, Ashley Ray, Tabithia Ross, Thomas Lee Selby, Wyatt T. Cramblet, Akash Patel, Sheetal Patel
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Epstein-Barr virus (EBV) latent membrane protein-1 (LMP1) activates numerous signal transduction pathways using its C-terminal activating regions. We reported that LMP1 increased global levels of sumoylated proteins, which aided the oncogenic nature