A High‐Throughput Drug Repurposing Strategy to Treat TBX2 and/or TBX3 Dependent Cancers.

Autor: Bleloch, Jenna S.¹ (AUTHOR), Lu, Sizhu² (AUTHOR), Khan, Saif Feroz¹ (AUTHOR), Serala, Karabo¹ (AUTHOR), Seraia, Elena³ (AUTHOR), Millar, Val³ (AUTHOR), Ebner, Daniel³ (AUTHOR), Goding, Colin² (AUTHOR) colin.goding@ludwig.ox.ac.uk, Prince, Sharon¹ (AUTHOR) sharon.prince@uct.ac.za

Publikováno v: Cancer Medicine. Oct2024, Vol. 13 Issue 19, p1-18. 18p.

The Lipid Droplet Protein DHRS3 Is a Regulator of Melanoma Cell State.

Autor: Johns E; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Ma Y; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Cell and Developmental Biology Program, Weill Cornell Graduate School of Medical Sciences, New York, New York, USA., Louphrasitthiphol P; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK., Peralta C; The Proteomics Resource Center at the Rockefeller University, New York, New York, USA., Hunter MV; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Raymond JH; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK., Molina H; The Proteomics Resource Center at the Rockefeller University, New York, New York, USA., Goding CR; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK., White RM; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Ludwig Institute for Cancer Research, University of Oxford, Oxford, UK.

Publikováno v: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2024 Oct 31. Date of Electronic Publication: 2024 Oct 31.

Overcoming Cancer Persister Cells by Stabilizing the ATF4 Promoter G‐quadruplex.

Autor: Xiao, Chengmei¹ (AUTHOR), Li, Yipu¹ (AUTHOR), Liu, Yushuang¹ (AUTHOR), Dong, Ruifang¹ (AUTHOR), He, Xiaoyu¹ (AUTHOR), Lin, Qing¹ (AUTHOR), Zang, Xin¹ (AUTHOR), Wang, Kaibo¹ (AUTHOR) kbwang@cpu.edu.cn, Xia, Yuanzheng^1,2 (AUTHOR) xiayz@cpu.edu.cn, Kong, Lingyi¹ (AUTHOR) cpu_lykong@126.com

Publikováno v: Advanced Science. 9/18/2024, Vol. 11 Issue 35, p1-21. 21p.

Melanocyte development and malignant melanoma

Autor: C R, Goding

Publikováno v: Forum (Genoa, Italy). 10(3)

Malignant melanoma is a notoriously aggressive disease that can affect relatively young individuals and whose incidence is rising at an alarming rate. Unlike many cancers, metastatic melanoma is poorly responsive to current therapies and mutations af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::37409569058b01c3a802b7a88c90be75
https://pubmed.ncbi.nlm.nih.gov/11007928

Recognition of the E-C4 element from the C4 complement gene promoter by the upstream stimulatory factor-1 transcription factor

Autor: M D, Galibert, L, Boucontet, C R, Goding, T, Meo

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(12)

Activation of complement gene expression plays a major role in the response to antigenic challenge. The induction of complement synthesis occurs primarily in liver and in macrophages and is mediated, at least in part, by increased transcription of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49dc6f570b4c461263da4c825aee4c45
https://pubmed.ncbi.nlm.nih.gov/9550420