Zobrazeno 1 - 10
of 113
pro vyhledávání: '"C. R. Ganellin"'
Publikováno v:
The Journal of Neuroscience. 33:5006-5016
In rodents, adrenergic signaling by norepinephrine (NE) in the hippocampus is required for the retrieval of intermediate-term memory. NE promotes retrieval via the stimulation of β1-adrenergic receptors, the production of cAMP, and the activation of
Autor:
C. R. Ganellin, M. E. Parsons
Pharmacology of Histamine Receptors presents a summary of the pharmacology of histamine receptors. It discusses the research and developments made in the use of histamine. It addresses the biological actions of the drug in various pathological instan
Publikováno v:
Biochemistry. 35:7917-7927
The structure of apamin-sensitive Ca(2+)-activated K+ channels has been investigated using high-affinity, photolabile azidoaryl derivatives of 125I-[alpha-formyl-Cys1]apamin and 125I-[epsilon-formyl-Lys4]-apamin. Labeling patterns suggest that simila
Autor:
J. W. Black, W. A. M. Duncan, J. C. Emmett, C. R. Ganellin, T. Hesselbo, M. E. Parsons, J. H. Wyllie
Publikováno v:
Agents and Actions. 43:91-96
Publikováno v:
Agents and Actions. 43:132-138
Publikováno v:
Agents and Actions. 43:139-143
Publikováno v:
Journal of Neurochemistry. 55:379-385
Histamine H1-receptors, visualized in the guinea pig heart by autoradiography using [125I]iodobolpyramine as a specific probe, are abundant in the nodal tissue and cardiac vessels but also occur heterogeneously in the myocardium. Following photoaffin
Autor:
J, Apelt, S, Grassmann, X, Ligneau, H H, Pertz, C R, Ganellin, J M, Arrang, J C, Schwartz, W, Schunack, H, Stark
Publikováno v:
Die Pharmazie. 60(2)
With the recent development of new hybrid compounds having histamine H3 receptor antagonist with combined histamine Ntau-methyltransferase (HMT) inhibitory potency an innovative approach was described in the research of novel lead compounds modulatin
Autor:
K, Kieć-Kononowicz, M, Wiecek, A, Sasse, X, Ligneau, S, Elz, C R, Ganellin, J C, Schwartz, H, Stark, W, Schunack
Publikováno v:
Die Pharmazie. 55(5)
In order to evaluate changes in the lipophilic part of designed carbamates concerning their potential histamine H3-receptor antagonist properties a new series of O-[3-(1H-imidazol-4-yl)propanol]carbamates was derived containing N-mono- or di-alkenyl,
Publikováno v:
Progress in medicinal chemistry. 38