Zobrazeno 1 - 10 of 10 pro vyhledávání: '"C. R. Bertozzi"'
2
Biosynthesis of sialylated lipooligosaccharides in Haemophilus ducreyi is dependent on exogenous sialic acid and not mannosamine. Incorporation studies using N-acylmannosamine analogues, N-glycolylneuraminic acid, and 13C-labeled N-acetylneuraminic acid
Autor: B, Schilling, S, Goon, N M, Samuels, S P, Gaucher, J A, Leary, C R, Bertozzi, B W, Gibson
Publikováno v: Biochemistry. 40(42)
Haemophilus ducreyi is a Gram-negative bacterium that causes chancroid, a sexually transmitted disease. Cell surface lipooligosaccharides (LOS) of H. ducreyi are thought to play important biological roles in host infection. The vast majority of H. du
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0440cfaa778d7494edf067b485d70623
https://pubmed.ncbi.nlm.nih.gov/11601991
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3
Characterizing glycosylation pathways
Autor: K J, Yarema, C R, Bertozzi
Publikováno v: Genome Biology
Numerous factors that influence cell-surface carbohydrate composition remain to be elucidated. The combination of novel biochemical and metabolism-based approaches with emerging genomic methods promises to accelerate efforts to understand glycosylati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7c46740263cc8b6a5e453fbcb516ae96
https://pubmed.ncbi.nlm.nih.gov/11387039
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4
Chemical synthesis of lymphotactin: a glycosylated chemokine with a C-terminal mucin-like domain
Autor: L A, Marcaurelle, L S, Mizoue, J, Wilken, L, Oldham, S B, Kent, T M, Handel, C R, Bertozzi
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 7(5)
The synthesis of a 93-residue chemokine, lymphotactin, containing eight sites of O-linked glycosylation, was achieved using the technique of native chemical ligation. A single GalNAc residue was incorporated at each glycosylation site using standard
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e81611a74fcc883fdda9d2a9db3529ef
https://pubmed.ncbi.nlm.nih.gov/11303872
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6
Metabolic delivery of ketone groups to sialic acid residues. Application To cell surface glycoform engineering
Autor: K J, Yarema, L K, Mahal, R E, Bruehl, E C, Rodriguez, C R, Bertozzi
Publikováno v: The Journal of biological chemistry. 273(47)
The development of chemical strategies for decorating cells with defined carbohydrate epitopes would greatly facilitate studies of carbohydrate-mediated cell surface interactions. This report describes a general strategy for engineering the display o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d1ba509824bd313341b92746c0285fca
https://pubmed.ncbi.nlm.nih.gov/9813021
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7
Identification of an N-acetylglucosamine-6-0-sulfotransferase activity specific to lymphoid tissue: an enzyme with a possible role in lymphocyte homing
Autor: K G, Bowman, S, Hemmerich, S, Bhakta, M S, Singer, A, Bistrup, S D, Rosen, C R, Bertozzi
Publikováno v: Chemistrybiology. 5(8)
The leukocyte adhesion molecule L-selection participates in the initial attachment of blood-borne lymphocytes to high endothelial venules (HEVs) during lymphocyte homing to secondary lymphoid organs, and contributes to leukocyte adhesion and extravas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d4bab5ca49341f224acc232522fca4e3
https://pubmed.ncbi.nlm.nih.gov/9710564
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8
Two selectins converge on sulphate. Leukocyte adhesion
Autor: S D, Rosen, C R, Bertozzi
Publikováno v: Current biology : CB. 6(3)
Selectins mediate the attachment of leukocytes to endothelial cells and to platelets under conditions of blood flow. Sulphation of the ligands for two of the selectins is required for optimal cell-cell interactions.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2f3214300828dbf7bd2debbb84591f1f
https://pubmed.ncbi.nlm.nih.gov/8805242
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9
Sulfated disaccharide inhibitors of L-selectin: deriving structural leads from a physiological selectin ligand
Autor: C R, Bertozzi, S, Fukuda, S D, Rosen
Publikováno v: Biochemistry. 34(44)
The selectins are a family of three adhesion molecules (L-, P-, and E-) that direct the interaction of circulating leukocytes with endothelial cells during the first step in recruitment to tissue sites. Their involvement in inflammatory disease makes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6195653e7bf0b8496b05e6b6df8635a1
https://pubmed.ncbi.nlm.nih.gov/7578028
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