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Akademický článek

Impact of cardiovascular evaluations and interventions on fall risk in older adults: a protocol for a scoping review and evidence map

Autor: Nathalie van der Velde, Liping Wang, Joost G Daams, Mariska M G Leeflang, Eveline P van Poelgeest, Anouschka C Pronk, Alfons G Hoekstra

Publikováno v: BMJ Open, Vol 12, Iss 4 (2022)

Introduction Cardiovascular disorders are increasingly recognised as important fall risk factors in older adults. Falls are a major public health problem in older adults, and therefore, effective interventions for reducing falls are essential for thi

Externí odkaz: https://doaj.org/article/4d69883c410a4727a0c744e84a626309

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Akademický článek

Candidate genetic variants and antidepressant-related fall risk in middle-aged and older adults

Autor: A. C. Pronk, L. J. Seppala, K. Trajanoska, N. Stringa, B. van de Loo, L. C. P. G. M. de Groot, N. M. van Schoor, F. Koskeridis, G. Markozannes, E. Ntzani, A. G. Uitterlinden, F. Rivadeneira, B. H. Stricker, N. van der Velde

Publikováno v: PLoS ONE, Vol 17, Iss 4 (2022)

Background Antidepressant use has been associated with increased fall risk. Antidepressant-related adverse drug reactions (e.g. orthostatic hypotension) depend partly on genetic variation. We hypothesized that candidate genetic polymorphisms are asso

Externí odkaz: https://doaj.org/article/84beff4542b64abc9f3865639a9c3891

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Are higher antidepressant plasma concentrations associated with fall risk in older antidepressant users?

Autor: A. C. Pronk, E. P. van Poelgeest, L. J. Seppala, K. J. Ploegmakers, B. H. Stricker, K. M. A. Swart, S. C. van Dijk, S. Oliai Araghi, L. C. P. G. M. de Groot, N. M. van Schoor, R. A. A. Mathôt, N. van der Velde

Publikováno v: European Geriatric Medicine, 14(1), 89-97. Elsevier Masson
Pronk, A C, van Poelgeest, E P, Seppala, L J, Ploegmakers, K J, Stricker, B H, Swart, K M A, van Dijk, S C, Oliai Araghi, S, de Groot, L C P G M, van Schoor, N M, Math?t, R A A & van der Velde, N 2023, ' Are higher antidepressant plasma concentrations associated with fall risk in older antidepressant users? ', European Geriatric Medicine, vol. 14, no. 1, pp. 89-97 . https://doi.org/10.1007/s41999-022-00742-1
European Geriatric Medicine 14 (2023) 1
European Geriatric Medicine, 14(1), 89-97
European geriatric medicine, 14(1), 89-97. Elsevier Masson

Purpose Antidepressants are well-established fall-risk increasing drugs (FRIDs) and therefore falls should be considered an important adverse drug event (ADE) of antidepressants. However, not all antidepressant users experience fall incidents and fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1625015d89f1dfc7624c9a98df4d0437
https://doi.org/10.1007/s41999-022-00742-1

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Applying systems thinking to unravel the mechanisms underlying orthostatic hypotension related fall risk

Autor: Liping Wang, Anouschka C. Pronk, Eveline P. van Poelgeest, Robert Briggs, Jurgen A.H.R. Claassen, Sofie Jansen, Marjolein Klop, Frederik J. de Lange, Carel C.G.M. Meskers, Vincent J. J. Odekerken, Stephen J. Payne, Marijke C. Trappenburg, Roland D. Thijs, Jeroen F. Uleman, Alfons G. Hoekstra, Nathalie van der Velde

Publikováno v: Geroscience. Springer International Publishing AG
GeroScience. Springer International Publishing AG
Wang, L, Pronk, A C, van Poelgeest, E P, Briggs, R, Claassen, J A H R, Jansen, S, Klop, M, de Lange, F J, Meskers, C C G M, Odekerken, V J J, Payne, S J, Trappenburg, M C, Thijs, R D, Uleman, J F, Hoekstra, A G & van der Velde, N 2023, ' Applying systems thinking to unravel the mechanisms underlying orthostatic hypotension related fall risk ', GeroScience . https://doi.org/10.1007/s11357-023-00802-9

Orthostatic hypotension (OH) is an established and common cardiovascular risk factor for falls. An in-depth understanding of the various interacting pathophysiological pathways contributing to OH-related falls is essential to guide improvements in di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d38129db272c8a8ffcf0e5d4a3d5320
https://pure.amc.nl/en/publications/applying-systems-thinking-to-unravel-the-mechanisms-underlying-orthostatic-hypotension-related-fall-risk(2cef388c-3871-4824-95ea-92456b2a00dc).html

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Depression, antidepressants and fall risk: therapeutic dilemmas—a clinical review

Autor: E. P. van Poelgeest, A. C. Pronk, N. van der Velde, Didi Rhebergen

Publikováno v: van Poelgeest, E P, Pronk, A C, Rhebergen, D & van der Velde, N 2021, ' Depression, antidepressants and fall risk : therapeutic dilemmas—a clinical review ', European Geriatric Medicine, vol. 12, no. 3, pp. 585-596 . https://doi.org/10.1007/s41999-021-00475-7
European Geriatric Medicine

Key summary points Aim To summarize the existing knowledge on fall risk associated with antidepressant use in older adults, including the underlying pathophysiology, and assist clinicians in (de-) prescribing antidepressants. Findings Untreated depre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5322a784c62685640387a53b796a0d
https://doi.org/10.1007/s41999-021-00475-7

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Positive and negative aspects of mental health after unspecified living kidney donation: A cohort study

Autor: Jacqueline van de Wetering, Mathilde C. Pronk, Emma K. Massey, Willem Weimar, Sohal Y. Ismail, Willij C. Zuidema

Publikováno v: British Journal of Health Psychology, 27(2), 374-389. Wiley-Blackwell

Objectives: Unspecified donors give a kidney to a stranger with end-stage kidney failure. There has been little research on the long-term impact of unspecified donation on mental health outcomes. The aim of this study was to assess the positive and n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182d489bb623787730db61e725c24a27
https://pure.eur.nl/en/publications/f4c45a29-ec28-43ed-ad30-cd85819644ff

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Relinquishing Anonymity in Living Donor Kidney Transplantation

Autor: Mathilde C, Pronk, Lisa, Burnapp, Marlies E J, Reinders, Emma K, Massey

Publikováno v: Transplant International, 35:10091. Wiley-Blackwell Publishing Ltd

Anonymous living donor kidney transplantation (LDKT) is performed in many countries and policies on anonymity differ. The UK is the only European country with a conditional policy, allowing pairs to break anonymity post-transplant. There is little ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b4ff6a232dfad29a4c9eb2b4b5f04f
https://doi.org/10.3389/ti.2022.10091

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Akademický článek

Regulation of protein synthesis in lymphoblasts from vanishing white matter patients

Autor: Barbara van Kollenburg, Adri A.M. Thomas, Gerre Vermeulen, Gesina A.M. Bertrand, Carola G.M. van Berkel, Jan C. Pronk, Christopher G. Proud, Marjo S. van der Knaap, Gert C. Scheper

Publikováno v: Neurobiology of Disease, Vol 21, Iss 3, Pp 496-504 (2006)

Leukoencephalopathy with vanishing white matter (VWM) is an inherited childhood white matter disorder, caused by mutations in the genes encoding eukaryotic initiation factor 2B (eIF2B). The present study showed that, while the eIF2B activity was redu

Externí odkaz: https://doaj.org/article/8159bc0d1f464732aa20f85a8cf2c051

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