Zobrazeno 1 - 10
of 1 720
pro vyhledávání: '"C. Powers"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 2305-2312 (2024)
Iminoiodinanes comprise a class of hypervalent iodine reagents that is often encountered in nitrogen-group transfer (NGT) catalysis. In general, transition metal catalysts are required to effect efficient NGT to unactivated olefins because iminoiodin
Externí odkaz:
https://doaj.org/article/51db98f5fb414dbf8e11886af21ba4bc
Autor:
Aanchal Mongia, Fatema Tuz Zohora, Noah G. Burget, Yeqiao Zhou, Diane C. Saunders, Yue J. Wang, Marcela Brissova, Alvin C. Powers, Klaus H. Kaestner, Golnaz Vahedi, Ali Naji, Gregory W. Schwartz, Robert B. Faryabi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Cellular composition and anatomical organization influence normal and aberrant organ functions. Emerging spatial single-cell proteomic assays such as Image Mass Cytometry (IMC) and Co-Detection by Indexing (CODEX) have facilitated the study
Externí odkaz:
https://doaj.org/article/19cd13bfd98d4db8ba44dc36c54204c9
Autor:
Xiangni Wu, Pin-I Chen, Robert L. Whitener, Matthew S. MacDougall, Vy M. N. Coykendall, Hao Yan, Yong Bin Kim, William Harper, Shiva Pathak, Bettina P. Iliopoulou, Allison Hestor, Diane C. Saunders, Erick Spears, Jean Sévigny, David M. Maahs, Marina Basina, Seth A. Sharp, Anna L. Gloyn, Alvin C. Powers, Seung K. Kim, Kent P. Jensen, Everett H. Meyer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Human regulatory T cells (Treg) suppress other immune cells. Their dysfunction contributes to the pathophysiology of autoimmune diseases, including type 1 diabetes (T1D). Infusion of Tregs is being clinically evaluated as a novel way to prevent or tr
Externí odkaz:
https://doaj.org/article/9eb5d3e2468049a48285a66700ca2b17
Autor:
Catherine Jacob-Dolan, Michelle Lifton, Olivia C. Powers, Jessica Miller, Nicole P. Hachmann, Mya Vu, Nehalee Surve, Camille R. Mazurek, Jana L. Fisher, Stefanie Rodrigues, Robert C. Patio, Trisha Anand, Mathieu Le Gars, Jerald Sadoff, Aaron G. Schmidt, Dan H. Barouch
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109716- (2024)
Summary: The viral vector-based COVID-19 vaccine Ad26.COV2.S has been recommended by the WHO since 2021 and has been administered to over 200 million people. Prior studies have shown that Ad26.COV2.S induces durable neutralizing antibodies (NAbs) tha
Externí odkaz:
https://doaj.org/article/319b65fba338482abc0eb9e090cc8de1
Autor:
Megan Delamer, Shubham Kanodia, Caleb I. Cañas, Simon Müller, Ravit Helled, Andrea S. J. Lin, Jessica E. Libby-Roberts, Arvind F. Gupta, Suvrath Mahadevan, Johanna Teske, R. Paul Butler, Samuel W. Yee, Jeffrey D. Crane, Stephen Shectman, David Osip, Yuri Beletsky, Andrew Monson, Leslie Hebb, Luke C. Powers, John P. Wisniewski, Jaime A. Alvarado-Montes, Chad F. Bender, Jiayin Dong, Te Han, Joe P. Ninan, Paul Robertson, Arpita Roy, Christian Schwab, Guđmundur Stefánsson, Jason T. Wright
Publikováno v:
The Astrophysical Journal Letters, Vol 962, Iss 2, p L22 (2024)
We confirm TOI-4201 b as a transiting Jovian-mass planet orbiting an early M dwarf discovered by the Transiting Exoplanet Survey Satellite. Using ground-based photometry and precise radial velocities from NEID and the Planet Finder Spectrograph, we m
Externí odkaz:
https://doaj.org/article/9109bd2a3664411b840237a62f27c616
Autor:
Catherine Jacob-Dolan, Jingyou Yu, Katherine McMahan, Victoria Giffin, Abishek Chandrashekar, Amanda J. Martinot, Tochi Anioke, Olivia C. Powers, Kevin Hall, David Hope, Jessica Miller, Nichole P. Hachmann, Benjamin Chung, Sarah Gardner, Daniel Sellers, Julia Barrett, Mark G. Lewis, Hanne Andersen, Harry Kleanthous, Ki-Woen Seo, Su Jeen Lee, Yong Wook Park, Hun Kim, Dan H. Barouch
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-9 (2023)
Abstract Despite the availability of several effective SARS-CoV-2 vaccines, additional vaccines will be required for optimal global vaccination. In this study, we investigate the immunogenicity and protective efficacy of the GBP510 protein subunit va
Externí odkaz:
https://doaj.org/article/2859911f0f034613a627935fa3b765b4
Autor:
Yulong Gong, Bingyuan Yang, Dingdong Zhang, Yue Zhang, Zihan Tang, Liu Yang, Katie C. Coate, Linlin Yin, Brittney A. Covington, Ravi S. Patel, Walter A. Siv, Katelyn Sellick, Matthew Shou, Wenhan Chang, E. Danielle Dean, Alvin C. Powers, Wenbiao Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Insufficient glucagon signalling results in hyperaminoacidemia, which drives adaptive proliferation of glucagon-producing α cells. Here the authors report that the amino acid sensitive calcium sensing receptor (CaSR) is necessary for α cell prolife
Externí odkaz:
https://doaj.org/article/654699dbaee24375b1033c131a876439
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Aziridines are useful intermediates, present in important synthetic targets. Here, the authors show a strategy for the synthesis of N-aryl aziridines based on N-aminopyridinium reagents followed by Ni-catalyzed C–N cross-coupling of N-pyridinium az
Externí odkaz:
https://doaj.org/article/ff16f918fcd14265a0104d34a161662d
Autor:
Kristie I. Aamodt, Alvin C. Powers
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
Insulin secretion by pancreatic β cells is a dynamic and highly regulated process due to the central importance of insulin in enabling efficient utilization and storage of glucose. Multiple regulatory layers enable β cells to adapt to acute changes
Externí odkaz:
https://doaj.org/article/c8e671a09adf42c8bd3768f279b24ea4
Autor:
Raphael Roger, Melissa A. Hilmes, Jonathan M. Williams, Daniel J. Moore, Alvin C. Powers, R. Cameron Craddock, John Virostko
Publikováno v:
BMC Medical Imaging, Vol 22, Iss 1, Pp 1-5 (2022)
Abstract Pancreas volume is reduced in individuals with diabetes and in autoantibody positive individuals at high risk for developing type 1 diabetes (T1D). Studies investigating pancreas volume are underway to assess pancreas volume in large clinica
Externí odkaz:
https://doaj.org/article/320a2564c6624a6198d4b82cc4af5dc1