Anticonvulsant activity of Mimosa pudica decoction

Autor: D.L Dawack, E. Ngo Bum, A Rakotonirina, S.V Rakotonirina, A. Jeker, Markus Schmutz, P Herrling, H. R. Olpe, C. Portet

Publikováno v: Fitoterapia. 75:309-314

The decoction of Mimosa pudica leaves given intraperitoneally at dose of 1000-4000 mg/kg protected mice against pentylentetrazol and strychnine-induced seizures. M. pudica had no effect against picrotoxin-induced seizures It also antagonized N-methyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69618845f47dc002c3625684566376ff
https://doi.org/10.1016/j.fitote.2004.01.012

Evaluation of insulation systems by in situ testing

Autor: D. Braga, I. Enache, M. Duran, C. Portet

Publikováno v: WIT Transactions on Modelling and Simulation.

Due to the global warming of the earth, the energy performance of buildings is now a crucial subject. In order to have an accurate comprehension of the energy loss of a building, we have developed real time in-situ tests for the thermal performance o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::100623ed1eba328846a14b2f70a7b1dc
https://doi.org/10.2495/cmem090141

CGP 37849 and CGP 39551: novel and potent competitive N-methyl-d-aspartate receptor antagonists with oral activity

Autor: Mario F. Pozza, C. Portet, H. Allgeier, John Grey Dr Dingwall, G.E. Fagg, Christof Angst, M. Schmutz, J. Baud, Helmut Bittiger, H.-R. Olpe, P. A. Baumann, Martin W. Steinmann, K. Thedinga, Roland Heckendorn, Derek E. Brundish

Publikováno v: British Journal of Pharmacology. 99:791-797

1 The pharmacological properties of CGP 37849 (DL-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid; 4-methyl-APPA) and its carboxyethylester, CGP 39551, novel unsaturated analogues of the N-methyl-D-aspartate (NMDA) receptor antagonist, 2-amino-5-ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35561589fda90727cb68d9f952ae2d16
https://doi.org/10.1111/j.1476-5381.1990.tb13008.x

Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7

Autor: Herman van der Putten, Ryuichi Shigemoto, David R. Hampson, Graham L. Collingridge, Fabrizio Gasparini, Thomas Knoepfel, Trevor J. Bushell, Rainer Kuhn, Andrei Rozov, Gilles Sansig, Vernon R. J. Clarke, Robert M. Duvoisin, Congxiao Zhang, Peter J. Flor, Nail Burnashev, Klaus Klebs, Valerie J. Collett, C. Portet, Markus Schmutz, Markus Schroeder

Publikováno v: Sansig, G, Bushel, T J, Clarke, V R J, Rozov, A, Burnashev, N, Portet, C, Gasparini, F, Schmutz, M, Klebs, K, Shigemoto, R, Flor, P J, Kuhn, R, Knoepfel, T, Schroeder, M, Hampson, D R, Collett, V J, Zhang, C X, Duvoisin, R M, Collingridge, G L & van der Putten, H 2001, ' Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 ', The Journal of Neuroscience, vol. 21, no. 22, pp. 8734-8745 .
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
The Journal of Neuroscience, 21(22), 8734-8745. Society for Neuroscience
Scopus-Elsevier

To study the role of mGlu7 receptors (mGluR7), we used homologous recombination to generate mice lacking this metabotropic receptor subtype (mGluR7−/−). After the serendipitous discovery of a sensory stimulus-evoked epileptic phenotype, we tested

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e24d394be60a528bc25d28e297ea4d9f
https://research.vu.nl/en/publications/d282b8e0-c09c-473a-af9f-4c2abedc1b96

Effect of carbamazepine, oxcarbazepine and lamotrigine on the increase in extracellular glutamate elicited by veratridine in rat cortex and striatum

Autor: P. C. Waldmeier, K. Stöcklin, Markus Schmutz, C. Portet, Pierre Martin

Publikováno v: Naunyn-Schmiedeberg's archives of pharmacology. 354(2)

Lamotrigine, carbamazepine and oxcarbazepine inhibit veratrine-induced neurotransmitter release from rat brain slices in concentrations corresponding to those reached in plasma or brain in experimental animals or humans after anticonvulsant doses, pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf44b5576cf940de6ef857175423fcb
https://pubmed.ncbi.nlm.nih.gov/8857593