Zobrazeno 1 - 10
of 128
pro vyhledávání: '"C. Plater-Zyberk"'
Publikováno v:
Clinical and Experimental Immunology. 98:442-447
SUMMARY Collagen-induced arthritis has been widely used as an animal model of rheumatoid arthritis. We have used this model with a view to determining potential therapeutic targets for the treatment of human disease. To do this we have attempted to m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e444ba8e3e43093e26bc18d509bc69
https://doi.org/10.1111/j.1365-2249.1994.tb05510.x
https://doi.org/10.1111/j.1365-2249.1994.tb05510.x
Publikováno v:
Journal of Immunological Methods. 136:259-267
We have employed a method for permeabilizing lymphocytes with the detergent saponin in order to detect an intracellular protein simultaneously with surface antigens by flow cytometry (FCM). Using monoclonal antibodies specific for the murine CD2 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1b89cdc705667224d01af0454b1499
https://doi.org/10.1016/0022-1759(91)90012-5
https://doi.org/10.1016/0022-1759(91)90012-5
Publikováno v:
Clinical and Experimental Immunology. 80:366-372
SUMMARY Twenty-six IgG-secreting and eight IgM-secreting hybridomas were derived from the synovia of two patients with rheumatoid arthritis (RA). Hybridomas were obtained by fusing a heteromyeloma cell line, SPAZ-4 with synovial mononuclear cells tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d540d82af193f7ea21389eb353b5cb
https://doi.org/10.1111/j.1365-2249.1990.tb03294.x
https://doi.org/10.1111/j.1365-2249.1990.tb03294.x
Publikováno v:
Arthritis and rheumatism. 44(11)
Oncostatin M (OSM) is a member of the interleukin-6 cytokine family, with well-documented effects on cell growth and differentiation. OSM also has proinflammatory and cartilage degradative properties. The aim of this study was to investigate the sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55a6342a238df67dc80ace63ae34f968
https://pubmed.ncbi.nlm.nih.gov/11710726
https://pubmed.ncbi.nlm.nih.gov/11710726
Autor:
J Vencovsky, J Niederlova, J Sinkora, CA Power, C Plater-Zyberk, Z Rehakova, O Krystufkova, S Ruzickova
Publikováno v:
Speaker abstracts 2001.
Background Inflammatory cell infiltration and synovial activation are important processes in rheumatoid arthritis. Chemotactic gradients of various chemokines are responsible for cell attraction and possibly for their activation. We have previously d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea849aa7f7b54e2267f9366866c4457b
https://doi.org/10.1136/annrheumdis-2001.528
https://doi.org/10.1136/annrheumdis-2001.528
Publikováno v:
Immunology. 88(2)
Collagen-induced arthritis in susceptible mice is widely accepted as an experimental model for human rheumatoid arthritis (RA). We have investigated the role of the Mac-1 integrin beta 2 in the development and maintenance of arthritis by means of in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c3f4f26921e8a8435a6f730dc1c70a
http://ora.ox.ac.uk/objects/uuid:f7ff3d05-2de8-470a-9e81-e377bae10ad8
http://ora.ox.ac.uk/objects/uuid:f7ff3d05-2de8-470a-9e81-e377bae10ad8
SUMMARY Rheumatoid arthritis (RA) is a chronic inflammatory disease that primarily affects synovial joints. Activated B lymphocytes and plasma cells are present in the synovial tissue and are thought to contribute to the immunopathology of the rheuma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b733215f67f50f2be90bface066a5a59
https://europepmc.org/articles/PMC1554435/
https://europepmc.org/articles/PMC1554435/
SUMMARY We describe the adoptive transfer of erosive arthritis to an immunodeficient host. Spleen cells from arthritic DBA/I mice (H-2q). immunized 4–6 weeks previously with bovine type II collagen in adjuvant, were transferred intraperitoncally in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c20e1fb5879152efab015e951765f52
https://europepmc.org/articles/PMC1554492/
https://europepmc.org/articles/PMC1554492/
Publikováno v:
Annals of the New York Academy of Sciences. 651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad6de30bfb5758233a7dbd81d064ef8
https://pubmed.ncbi.nlm.nih.gov/1376074
https://pubmed.ncbi.nlm.nih.gov/1376074
Publikováno v:
Rheumatoid Arthritis ISBN: 9783642761911
The presence of autoantibodies such as rheumatoid factor (RF) in patients with rheumatoid arthritis (RA) prompted the concept that abnormalities in the immune system may be important in the development of the disease [70]. This in turn led to intensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b13790143d998106e8d02f98d726be70
https://doi.org/10.1007/978-3-642-76189-8_9
https://doi.org/10.1007/978-3-642-76189-8_9