The Booroola mutation in sheep is associated with an alteration of the bone morphogenetic protein receptor-IB functionality

Autor: Philippe Monget, Danielle Monniaux, Stéphane Fabre, P Mulsant, Alice Pierre, J Pohl, C. Pisselet, F Lecerf

Publikováno v: Journal of Endocrinology
Journal of Endocrinology, BioScientifica, 2003, 177, pp.435-444

The hyperprolificacy phenotype of Booroola ewes is due to the presence of the FecB(B) allele at the FecB locus, recently identified as a single amino acid substitution (Q249R) in the bone morphogenetic protein (BMP) type-IB receptor (BMPR1B), and is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c688b3b1606f4e2a024349ee072666b2
https://doi.org/10.1677/joe.0.1770435

Consequences of the Presence of the Booroola F Gene on the Intraovarian Insulin-Like Growth Factor System and Terminal Follicular Maturation in Mérinos d’Arles Ewes1

Autor: Jean-Michel Elsen, C. Pisselet, D. Monniaux, Philippe Monget, Joël Fontaine

Publikováno v: Biology of Reproduction. 63:1205-1213

In sheep, the presence of the Booroola F gene has several important consequences for ovarian function. This study investigated the consequences of the presence of the F gene for the insulin-like growth factor (IGF) system in the ewe ovary. Studies we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::891b23ea1ac551a821a53771d70b2252
https://doi.org/10.1095/biolreprod63.4.1205

THE XENOTRANSPLANTATION OF GOAT AND HUMAN HEMATOPOIETIC CELLS TO SHEEP FETUSES1

Autor: C. Pisselet, H. Salmon, Sylvie Canepa, P. Popescu, J. L. Dacheux, Alain Locatelli, C. Cotinot, Y. Le Vern, D. Kerboeuf, A. Thomas, G. Colas, P. Hollands

Publikováno v: Transplantation. 67:984-990

Hematopoietic xenografts were carried out in three experiments using goat fetal liver (44-48 days, experiments I and II) or purified human CD 34+ cells (experiment III) as the donor cells. Recipients were sheep fetuses at 41-47 days of gestation. Goa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ef1ec7fe67879c784e1f9844183432ab
https://doi.org/10.1097/00007890-199904150-00009

Molecular basis of bone morphogenetic protein-4 inhibitory action on progesterone secretion by ovine granulosa cells

Autor: P. Monget, Stéphane Fabre, D Monniaux, B Mandon-Pépin, J. Dupont, Alice Pierre, C Pisselet

Publikováno v: Journal of Molecular Endocrinology
Journal of Molecular Endocrinology, BioScientifica, 2004, 33, pp.805-817

We have recently reported that bone morphogenetic protein-4 (BMP-4) can inhibit progesterone production by ovine granulosa cells (GCs). Here, we have investigated the underlying mechanisms of this effect in basal as well as in FSH-induced conditions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26eb71fd1fc1408d69f3310de45068e2
https://hal.inrae.fr/hal-02674170

Differences in splicing of mRNA encoding LH receptor in theca cells according to breeding season in ewes

Autor: C. Pisselet, AS Lesport, R Salesse, D. Monniaux, L. Abdennebi, D Grebert, J.J. Remy

Publikováno v: Reproduction-Cambridge-Supplement
Reproduction-Cambridge-Supplement-, Society for Reproduction and Fertility, 2002, 123, pp.819-826
Reproduction (Cambridge, England)
Reproduction (Cambridge, England), 2002, 123(6), pp.819-826

Splice variants of mRNA encoding the LH receptor (LHR) during follicular development were characterized in cyclic and non-cyclic ewes. Granulosa and theca cells were collected from individual follicles. After amplification by RT-PCR of a region situa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae198e1cb60657d1b4561e26fa4853de
https://hal.inrae.fr/hal-02677032