Zobrazeno 1 - 10
of 64
pro vyhledávání: '"C. Pimoule"'
Autor:
A. Jardin, K.E. Andersson, C.C. Schulman, D. Graham, S. Arbilla, C. Pimoule, S.Z. Langer, J.M. Buzelin, J.M.C.H. de la Rosette, T.J. Chrismas, C.R. Chapple
Publikováno v:
European Urology. 29:374-384
Publikováno v:
Annals of the New York Academy of Sciences. 763:112-124
Recent studies have shown that cirazoline, an alpha 1-adrenoceptor agonist, has greater affinity than do other imidazoline or guanidinium compounds at imidazoline recognition sites. In this report we used [3H]cirazoline as a probe to characterize imi
Autor:
P. GEORGE, F. BORG, S. O'CONNOR, J. LECHAIRE, S. ARBILLA, C. PIMOULE, D. GRAHAM, T. WEDZIKOWSKY, S.Z. LANGER
Publikováno v:
European Journal of Medicinal Chemistry. 30:299s-310s
Autor:
E. Gautier, S.Z. Langer, Hans Schoemaker, Philippe Manoury, Peter E. Hicks, F Lefèvre-Borg, J. Lechaire, F. Pierre, S.E. O'Connor, C. Pimoule
Publikováno v:
British Journal of Pharmacology. 109:1282-1289
1. Phenylephrine-induced contractions of rabbit isolated trigone and urethra were antagonized in a competitive manner by alfuzosin (pA2 7.44 and 7.30, respectively) and prazosin. 2. The characteristics of [3H]-prazosin binding to human prostatic aden
Publikováno v:
Life sciences. 54(21)
α 1 -Adrenoceptors (ARs) play an important role in mediating human prostatic smooth muscle contraction. In the present study cDNA fragments covering different domains of 3 α 1 -AR subtypes ( α 1b , α 1c and α 1d ) were generated from human prost
Autor:
I, Angel, H, Schoemaker, S, Arbilla, A M, Galzin, C, Berry, R, Niddam, C, Pimoule, M, Sevrin, A, Wick, S Z, Langer
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(3)
One novel, potent and selective alpha-2 adrenoceptor antagonist is 2-(4,5-dihydro-1H-imidazol-2-yl)-1,2,4,5-tetrahydro-2- propylpyrrolo[3,2,1-hi]-indole hydrochloride (SL 84.0418). It inhibits with high affinity the radioligand binding to rat cortica
Publikováno v:
Clinical neuropharmacology. 15
Autor:
Salomon Z. Langer, Henri Lôo, M. F. Poirier, C. Pimoule, H. Schoemaker, Daniel Sechter, Anne-Marie Galzin, A. Segonzac, E. Zarifian, Chawki Benkelfat
Publikováno v:
Biological Psychiatry. 22:287-302
In the platelets of normal healthy volunteers (n = 8) taking chlorimipramine (50 mg/day) for 1 week, the saturable uptake of [3H]5-hydroxytryptamine (5-HT) was fully inhibited at the end of the week, but returned to control values after 2 weeks washo
Autor:
M. F. Poirier, A. M. Galzin, C. Pimoule, H. Schoemaker, K. H. Le Quan Bui, P. Meyer, C. Gay, H. Loo, S. Z. Langer
Publikováno v:
Psychopharmacology. 94:521-526
Platelet [3H]-5HT uptake, [3H]-imipramine binding and endogenous 5HT levels were measured in healthy volunteers during short-term (20 days) administration of lithium, and following its withdrawal. The Vmax of [3H]-5HT uptake was significantly decreas
Publikováno v:
Neurochemical Research. 4:517-527
GABA-transaminase has been characterized in cultured astrocytes. It is identical to the synaptosomal and perikaryal enzyme in terms of charge, molecular weight, and stability, but it differs in its affinity for GABA, which is much higher in the glial