Zobrazeno 1 - 10
of 50
pro vyhledávání: '"C. Peter Bengtson"'
Autor:
Simon F. Merz, C. Peter Bengtson, Clara Tepohl, Anna M. Hagenston, Hilmar Bading, Carlos Bas-Orth
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Glutamate toxicity is a pathomechanism that contributes to neuronal cell death in a wide range of acute and chronic neurodegenerative and neuroinflammatory diseases. Activation of the N-methyl-D-aspartate (NMDA)-type glutamate receptor and b
Externí odkaz:
https://doaj.org/article/648e0668ce8748c3b8ce691c929aede6
Autor:
Oskar Staufer, Sebastian Weber, C. Peter Bengtson, Hilmar Bading, Joachim P. Spatz, Amin Rustom
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 7, Iss 1, Pp 296-301 (2016)
The functional fusion of “living” biomaterial (such as cells) with synthetic systems has developed into a principal ambition for various scientific disciplines. In particular, emerging fields such as bionics and nanomedicine integrate advanced na
Externí odkaz:
https://doaj.org/article/676964026e23487cbf331451dc748377
Publikováno v:
Cell Reports, Vol 12, Iss 8, Pp 1353-1366 (2015)
The health of neurons is critically dependent on the relative signaling intensities of survival-promoting synaptic and death-inducing extrasynaptic NMDA receptors. Here, we show that BDNF is a regulator of this balance and promotes neuroprotection by
Externí odkaz:
https://doaj.org/article/cd7288d8f0b54e38967aa4c2c7f2cc51
Autor:
Hanke Gwendolyn Bauersachs, C. Peter Bengtson, Ursula Weiss, Andrea Hellwig, Celia García-Vilela, Bastienne Zaremba, Henrik Kaessmann, Priit Pruunsild, Hilmar Bading
Publikováno v:
Neuroscience. 484:83-97
Studies in rodent models of acute and chronic neurodegenerative disorders have uncovered that glutamate-induced excitotoxic cell death is mediated primarily by extrasynaptic N-methyl-d-aspartate receptors (NMDARs). Rodent neurons can also build up in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6faea69bee84f4e1887f723073bdb91
https://doi.org/10.1016/j.neuroscience.2021.12.026
https://doi.org/10.1016/j.neuroscience.2021.12.026
Autor:
Kristin Oberländer, Victoria Witte, Anne Stephanie Mallien, Peter Gass, C. Peter Bengtson, Hilmar Bading
Publikováno v:
Learning & Memory. 29:55-70
Differences in the learning associated transcriptional profiles between mouse strains with distinct learning abilities could provide insight into the molecular basis of learning and memory. The inbred mouse strain DBA/2 shows deficits in hippocampus-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b8c66d76b306b725ddf1ebd723f468
https://doi.org/10.1101/lm.053527.121
https://doi.org/10.1101/lm.053527.121
Publikováno v:
Journal of Biological Chemistry. 299:104671
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6b98a070b4e57076c1d69a834d91986
https://doi.org/10.1016/j.jbc.2023.104671
https://doi.org/10.1016/j.jbc.2023.104671
Publikováno v:
The Journal of Physiology. 598:633-650
Key points We present a novel protocol to quantify extrasynaptic NMDA receptor function utilizing the semi-selective activation of extrasynaptic receptors by ambient extracellular glutamate in acute brain slices from adult rats. We use whole cell pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928b655e09a72195ec2d05ce3d82afc6
https://doi.org/10.1113/jp278362
https://doi.org/10.1113/jp278362
Autor:
Kristin, Oberländer, Victoria, Witte, Anne Stephanie, Mallien, Peter, Gass, C Peter, Bengtson, Hilmar, Bading
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 29(2)
Differences in the learning associated transcriptional profiles between mouse strains with distinct learning abilities could provide insight into the molecular basis of learning and memory. The inbred mouse strain DBA/2 shows deficits in hippocampus-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20b2b45d2ddbc1cb19dbda76ea05c271
https://pubmed.ncbi.nlm.nih.gov/35042829
https://pubmed.ncbi.nlm.nih.gov/35042829
Publikováno v:
Science. 370
Interface targeting skirts excitotoxicity Nearly all attempts to use traditional N -methyl- d -aspartate receptor (NMDAR) antagonists to treat neurodegenerative diseases have failed. This is because NMDARs are not only promoters of neuronal death but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce10811b6c5b4b5bb054cfc4389cf13f
https://doi.org/10.1126/science.aay3302
https://doi.org/10.1126/science.aay3302
Autor:
Carlos Bas-Orth, Clara Tepohl, Hilmar Bading, C. Peter Bengtson, Anna M. Hagenston, Simon F. Merz
Publikováno v:
Molecular Brain
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Molecular Brain, Vol 13, Iss 1, Pp 1-14 (2020)
Glutamate toxicity is a pathomechanism that contributes to neuronal cell death in a wide range of acute and chronic neurodegenerative and neuroinflammatory diseases. Activation of theN-methyl-D-aspartate (NMDA)-type glutamate receptor and breakdown o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25a6ef9326d2166926fd5291b33c2c7
http://europepmc.org/articles/PMC7489219
http://europepmc.org/articles/PMC7489219