Zobrazeno 1 - 10
of 55
pro vyhledávání: '"C. P. Worman"'
Culture studies of peripheral blood mononuclear cells from 7 entirely typical cases of hairy cell leukemia showed that after culture in the presence of PHA for 2--5 days, the predominant cell type changed from E- SIg+ CIg+ gamma FcR+ muFcR+ hairy cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f8dbd922c5be4f51336e9749d52680
https://ora.ox.ac.uk/objects/uuid:ef792cdb-3d57-44b1-adb8-fe81c0582ed2
https://ora.ox.ac.uk/objects/uuid:ef792cdb-3d57-44b1-adb8-fe81c0582ed2
Morphological and Immunological Similarity of the Monocytes from Pure and Mixed Monocytic Leukaemias
Autor:
Robert Sibbald, C. P. Worman, Bryon E. Roberts, C. R. Barker, Roger J. Flemans, G. F. Burns, J. C. Cawley
Publikováno v:
Scandinavian Journal of Haematology. 21:233-242
Morphological and immunological marker data on a patient with 'pure' monocytic leukaemia are presented and compared with those of 6 cases of clearly mixed myelomonocytic leukaemia with a variable monocytic component. In all patients studied, the leuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0195b1d91384bec451d70dd7aa7a082
https://doi.org/10.1111/j.1600-0609.1978.tb00358.x
https://doi.org/10.1111/j.1600-0609.1978.tb00358.x
Publikováno v:
Scandinavian Journal of Haematology. 30:223-226
In all 11 patients with hairy-cell leukaemia (HCL) tested, a high percentage of peripheral blood and splenic (3 cases) hairy cells (HCs) reacted with 2 B-cell-specific monoclonal antibodies (FMC1 and FMC7), but failed to stain with 5 monocyte/macroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6a9cade3ad54aba416bbf0003e4326
https://doi.org/10.1111/j.1600-0609.1983.tb01479.x
https://doi.org/10.1111/j.1600-0609.1983.tb01479.x
Autor:
Kingston H. G. Mills, C. P. Worman, J. C. Cawley, P. C. L. Beverley, Ah Goldstone, D. C. Linch
Publikováno v:
Europe PubMed Central
8 patients with acute myeloid leukaemia (AML), either at presentation or in remission, had normal T-cell subsets as defined by Fc receptors and monoclonal antisera. In contrast, a persistant excess of T lymphocytes staining with Leu 2a (defining supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6ea7cd9380c873f392e05828da1008c
https://doi.org/10.1111/j.1600-0609.1982.tb00517.x
https://doi.org/10.1111/j.1600-0609.1982.tb00517.x
Autor:
J. C. Cawley, C. P. Worman
Publikováno v:
Scandinavian Journal of Haematology. 29:338-344
In 17 tests in 14 patients with hairy-cell leukaemia (HCL), peripheral blood Leu 2a+ and 3a+ suppressor and helper cells were present in normal mean percentage (3a+ 63 + 15 %, normal 64 + 8%; 2a+ 39 + 16%, normal 34 + 8%), absolute (3a+ 0.8 + 0.4 tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53518dadc3d8cf36c47538779b7f597b
https://doi.org/10.1111/j.1600-0609.1982.tb00604.x
https://doi.org/10.1111/j.1600-0609.1982.tb00604.x
Publikováno v:
Leukemia & Lymphoma. 24:327-333
The control of cell growth and differentiation in B-cell malignancies may be regulated by the autocrine production of cytokines, several of which have been implicated in the growth and survival of B-cells. The effect of interferon-alpha (IFN) therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad6f74afe9bed1df6a77ccdf95f674d
https://doi.org/10.3109/10428199709039020
https://doi.org/10.3109/10428199709039020
Publikováno v:
Leukemia & Lymphoma. 18:159-162
The proliferation and survival of B-chronic lymphocytic leukaemia (B-CLL) cells may be regulated by autocrine growth factor loops. Furthermore, it has been suggested the reduction in lymphocytosis following therapy with interferon-alpha may be associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ef7de6eef62e39de763c13f321520f
https://doi.org/10.3109/10428199509064937
https://doi.org/10.3109/10428199509064937
Publikováno v:
British Journal of Haematology. 88:268-274
The bcl-2 oncoprotein, which is involved in the t(14,18) translocation, protects cells against apoptosis. We examined the effects of interferon-alpha (IFN-alpha) on bcl-2 protein expression and apoptosis in B-chronic lymphocytic leukaemia (B-CLL) cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469c320c47416d9ffa16cc7bde7e7cc0
https://doi.org/10.1111/j.1365-2141.1994.tb05017.x
https://doi.org/10.1111/j.1365-2141.1994.tb05017.x
Publikováno v:
Leukemia & Lymphoma. 7:473-480
Recent studies have shown that, when used in early stage disease, interferon-alpha (IFN-alpha) can produce a fall in the number of malignant cells in the peripheral blood of patients with B-CLL. In this study, we investigated the effect of IFN-alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed9842ce6b832ec8bd619008ae82cbc
https://doi.org/10.3109/10428199209049804
https://doi.org/10.3109/10428199209049804
Publikováno v:
Journal of Immunological Methods. 142:147-155
A trypsin-like serine esterase (SE) is known to be present in cultured cells with cytolytic potential. The distribution pattern of this enzyme in haematological cells and body tissues has been assessed using a method which permits rapid identificatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ca819cecd12ac0697934c282cb3d326
https://doi.org/10.1016/0022-1759(91)90101-k
https://doi.org/10.1016/0022-1759(91)90101-k