Zobrazeno 1 - 10
of 21
pro vyhledávání: '"C. P. Anglin"'
Autor:
Katie McMahen, Shannon H. A. Guichon, C. D. Anglin, Les M. Lavkulich, Susan J. Grayston, Suzanne W. Simard
Publikováno v:
Ecology and Evolution, Vol 12, Iss 11, Pp n/a-n/a (2022)
Abstract Plants alter soil biological communities, generating ecosystem legacies that affect the performance of successive plants, influencing plant community assembly and successional trajectories. Yet, our understanding of how microbe‐mediated so
Externí odkaz:
https://doaj.org/article/b4be172545194d699a6d7974e56c7db3
Publikováno v:
Inflammation. 19:717-725
C5a is a biologically active polypeptide formed during the course of complement activation and is known to possess histamine-releasing and neutrophil chemotactic properties. In the present study, we have demonstrated that C5a can regulate electrolyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::306222b85faafaa777e2a7aaa154c6a9
https://doi.org/10.1007/bf01534574
https://doi.org/10.1007/bf01534574
Publikováno v:
Inflammation. 19:503-515
Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract that includes ulcerative colitis and Crohn's disease. Leukotriene B4 is thought to be a prominent proinflammatory mediator in these diseases, in that leukotri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dff1e9702b783d18d1527374372e08a
https://doi.org/10.1007/bf01539131
https://doi.org/10.1007/bf01539131
Autor:
D. Spangler, James F Kachur, C. P. Anglin, Snyder Jp, Stella Siu-Tzyy Yu, T. D. Penning, S. W. Djuric, R H Keith, D. J. Fretland, Julie M Miyashiro
Publikováno v:
Journal of Medicinal Chemistry. 38:858-868
Our previous reports have highlighted the first-generation leukotriene B 4 (LTB 4 ) receptor antagonist SC-41930 (7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-3,4-dihydro-8-propyl-2H-1-benzopyran-2-carboxylic acid) which has potent oral, topical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773bc091d74866da34ab5e26f8eef4b5
https://doi.org/10.1021/jm00006a002
https://doi.org/10.1021/jm00006a002
Autor:
D. J. Fretland, D. L. Widomski, Timothy S. Gaginella, James F. Kachur, T.J. Maziasz, C. P. Anglin, B.S. Tsai, Stella S. Yu, Tadimeti S. Rao, R. E. Walsh, R H Keith, Stephen H Docter, Stevan W. Djuric, D Villani-Price
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:811-816
The Structure Activity Relationship (SAR) studies leading to the identification of a novel high potency Leukotriene B4 receptor antagonist SC-53228 are delineated. This compound shows excelled pharmacodynamic efficacy in animal models of inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ae9db9d931f92a43a7315a6d0686fdb
https://doi.org/10.1016/s0960-894x(01)80853-2
https://doi.org/10.1016/s0960-894x(01)80853-2
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 44:61-65
Granulocyte diapedesis in response to the generation of defined chemotaxins such as leukotriene B4 (LTB4), 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE], C5a, platelet activating factor and others is a hallmark of the inflammatory process that is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb31b38c8783ec19e7b5284bf87711da
https://doi.org/10.1016/0952-3278(91)90146-v
https://doi.org/10.1016/0952-3278(91)90146-v
Autor:
D. L. Widomski, Timothy S. Gaginella, R. E. Walsh, D. J. Fretland, C. P. Anglin, Stuart Levin
Publikováno v:
Journal of Leukocyte Biology. 49:283-288
The products of the 5- and 12-lipoxygenase (5-LO, 12-LO) pathways of arachidonic acid metabolism are implicated as proinflammatory mediators in a number of disease states. 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE] is present in large quantities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a6f16183465b00a417935060de0fa7
https://doi.org/10.1002/jlb.49.3.283
https://doi.org/10.1002/jlb.49.3.283
Publikováno v:
Agents and Actions. 34:5-7
Cleavage of the fifth component of complement yields C5a, a potent neutrophil (PMN) and eosinophil chemoattractant, and modulator of microvascular permeability. Similarly, but to a lesser degree, C3 increases vascular permeability and histamine relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd74c39f8d0223745969d303be377a3
https://doi.org/10.1007/bf01993222
https://doi.org/10.1007/bf01993222
Autor:
B S, Tsai, R H, Keith, W E, Perkins, R E, Walsh, C P, Anglin, P W, Collins, A W, Gasiecki, R F, Bauer, P H, Jones, T S, Gaginella
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 275(1)
Prostaglandins (PGs) in the E-series exhibit potent gastric antisecretory activity, but can also cause diarrhea, which is mediated via PGE receptors. SC-46275, an omega-chain cyclopentenyl analog of the E-type PG enisoprost, was evaluated with other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c4ab637c2c25d71a5c5de327ef276d2
https://pubmed.ncbi.nlm.nih.gov/7562572
https://pubmed.ncbi.nlm.nih.gov/7562572
Autor:
D. J. Fretland, J. P. McKearn, M. Bremer, Stephen H. Docter, S. K. Paulson, S. W. Djuric, D. L. Widomski, Stella S. Yu, T. D. Penning, C. P. Anglin, Peter C. Isakson
Publikováno v:
Inflammation. 19(2)
Leukotriene B4 (LTB4) and 12(R)-hydroxyeicosatetraenoic acid [12(R)-HETE] are proinflammatory products of arachidonic acid metabolism that have been implicated as mediators in a number of inflammatory diseases. When injected intradermally into the gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff6cc962df83f387f35eae2f19703a7
https://pubmed.ncbi.nlm.nih.gov/7601505
https://pubmed.ncbi.nlm.nih.gov/7601505