Zobrazeno 1 - 5
of 5
pro vyhledávání: '"C. P. Allott"'
Autor:
David Anthony Roberts, A.C. Reid, S. T. Russell, C. P. Allott, Richard W. A. Luke, A.A. Oldham, Eric Fisher, R.J. Pearce, Michael Dennis, Robert Hugh Bradbury, J. S. Major, David Alan Rudge
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 3:899-904
Quinoline-, 1,5-naphthyridine- and pyridine-based angiotensin II antagonists are reported. The more potent compounds gave IC 50 values of ca 0.01 μM in a guinea pig adrenal membrane binding assay and intravenous ED 50 values in the range 0.1–1.0 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b28a6bb94b3936d2944b0b39bc7ad1f9
https://doi.org/10.1016/s0960-894x(00)80689-7
https://doi.org/10.1016/s0960-894x(00)80689-7
Autor:
R H, Bradbury, C P, Allott, M, Dennis, J A, Girdwood, P W, Kenny, J S, Major, A A, Oldham, A H, Ratcliffe, J E, Rivett, D A, Roberts
Publikováno v:
Journal of Medicinal Chemistry. 36:1245-1254
A novel series of nonpeptidic angiotensin II (AII) receptor antagonists is reported, derived from linkage of the biphenylcarboxylic acid or biphenylyltetrazole moiety found in previously described antagonists via a methyleneoxy chain to the 4-positio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b778e7d6e622d9f7bfcebc5ba89f265f
https://doi.org/10.1021/jm00061a016
https://doi.org/10.1021/jm00061a016
Autor:
J. S. Major, David A. Roberts, Michael Dennis, S. T. Russell, C. P. Allott, Robert James Pearce, Brian B. Masek, John Revill, A. A. Oldham, Eric Fisher, N. Rankine, Robert H. Bradbury
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d478855f0ca3a92f12168025eeba3c0
https://doi.org/10.1002/chin.199321171
https://doi.org/10.1002/chin.199321171
Autor:
R H, Bradbury, C P, Allott, M, Dennis, E, Fisher, J S, Major, B B, Masek, A A, Oldham, R J, Pearce, N, Rankine, J M, Revill
Publikováno v:
Journal of Medicinal Chemistry. 35:4027-4038
A novel series of nonpeptidic angiotensin II (AII) receptor antagonists is reported, derived from linkage of the biphenylcarboxylic acid or biphenylyltetrazole moiety found in previously described antagonists via a methyleneoxy chain to the 4-positio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4d27cbfb4d59f00f6558166954c411
https://doi.org/10.1021/jm00100a007
https://doi.org/10.1021/jm00100a007
Publikováno v:
Breakdown in Human Adaptation to ‘Stress’ ISBN: 9789401079754
Breakdown in Human Adaptation to ‘Stress’ ISBN: 9789401180665
Breakdown in Human Adaptation to ‘Stress’ ISBN: 9789401180665
Accumulating evidence suggests that subjects with either borderline or established essential hypertension exhibit abnormal haemodynamic responses to acute stress, including psychoemotional challenge (see reviews by Brod, 1982, and Folkow, 1982). In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69191dcdc8604071a36b1638f20614b7
https://doi.org/10.1007/978-94-009-3285-2_37
https://doi.org/10.1007/978-94-009-3285-2_37
