Zobrazeno 1 - 10
of 141
pro vyhledávání: '"C. Osburn"'
Autor:
Devin Wahl, Sydney J. Risen, Shelby C. Osburn, Tobias Emge, Sadhana Sharma, Vincenzo S. Gilberto, Anushree Chatterjee, Prashant Nagpal, Julie A. Moreno, Thomas J. LaRocca
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-18 (2024)
Abstract Neuroinflammation contributes to impaired cognitive function in brain aging and neurodegenerative disorders like Alzheimer’s disease, which is characterized by the aggregation of pathological tau. One major driver of both age- and tau-asso
Externí odkaz:
https://doaj.org/article/5605af35a84d4c0f8db032124aca9f4d
Autor:
J. J. Middelburg, C. Osburn, J. Nyunja, F. J. R. Meysman, R. Merckx, H. J. Hughes, G. Govers, F. Dehairs, A. V. Borges, G. Abril, S. Bouillon
Publikováno v:
Biogeosciences, Vol 6, Iss 11, Pp 2475-2493 (2009)
The Tana River basin (TRB) is the largest in Kenya (~120 000 km2). We conducted a survey during the dry season throughout the TRB, analyzing a broad suite of biogeochemical parameters. Biogeochemical signatures in headwater streams were highly variab
Externí odkaz:
https://doaj.org/article/acdca001a2c048778247ee4a56fae571
Autor:
Paulo H. C. Mesquita, Shelby C. Osburn, Joshua S. Godwin, Michael D. Roberts, Andreas N. Kavazis
Publikováno v:
Physiological Reports, Vol 10, Iss 24, Pp n/a-n/a (2022)
Abstract We investigated the effects of aging and long‐term physical activity on markers of mitochondrial function and dynamics in the cortex and cerebellum of female rats. Additionally, we interrogated markers of oxidative damage and antioxidants.
Externí odkaz:
https://doaj.org/article/4253d508a5584381a1168a5829a4a9f6
Autor:
Christopher G. Vann, Casey L. Sexton, Shelby C. Osburn, Morgan A. Smith, Cody T. Haun, Melissa N. Rumbley, Petey W. Mumford, Nathan T. Montgomery, Bradley A. Ruple, James McKendry, Jonathan Mcleod, Adil Bashir, Ronald J. Beyers, Matthew S. Brook, Kenneth Smith, Philip J. Atherton, Darren T. Beck, James R. McDonald, Kaelin C. Young, Stuart M. Phillips, Michael D. Roberts
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
We evaluated the effects of higher-load (HL) versus (lower-load) higher-volume (HV) resistance training on skeletal muscle hypertrophy, strength, and muscle-level molecular adaptations. Trained men (n = 15, age: 23 ± 3 years; training experience: 7
Externí odkaz:
https://doaj.org/article/5aa99eb02ed84b8f8de7ffd18497c62f
Autor:
Casey L. Sexton, Joshua S. Godwin, Mason C. McIntosh, Bradley A. Ruple, Shelby C. Osburn, Blake R. Hollingsworth, Nicholas J. Kontos, Philip J. Agostinelli, Andreas N. Kavazis, Tim N. Ziegenfuss, Hector L. Lopez, Ryan Smith, Kaelin C. Young, Varun B. Dwaraka, Andrew D. Frugé, Christopher B. Mobley, Adam P. Sharples, Michael D. Roberts
Publikováno v:
Cells, Vol 12, Iss 2, p 263 (2023)
We sought to determine the skeletal muscle genome-wide DNA methylation and mRNA responses to one bout of lower load (LL) versus higher load (HL) resistance exercise. Trained college-aged males (n = 11, 23 ± 4 years old, 4 ± 3 years self-reported tr
Externí odkaz:
https://doaj.org/article/29bd0a4ee47449afa3ce4d6a550b186a
Autor:
Bradley A. Ruple, Joshua S. Godwin, Paulo H. C. Mesquita, Shelby C. Osburn, Casey L. Sexton, Morgan A. Smith, Jeremy C. Ogletree, Michael D. Goodlett, Joseph L. Edison, Arny A. Ferrando, Andrew D. Fruge, Andreas N. Kavazis, Kaelin C. Young, Michael D. Roberts
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Resistance training increases muscle fiber hypertrophy, but the morphological adaptations that occur within muscle fibers remain largely unresolved. Fifteen males with minimal training experience (24±4years, 23.9±3.1kg/m2 body mass index) performed
Externí odkaz:
https://doaj.org/article/105be08bfa6f445e93fcef59c22400d8
Autor:
Shelby C. Osburn, Paul A. Roberson, Jessica A. Medler, Jacob Shake, Robert D. Arnold, Nima Alamdari, Luke R. Bucci, Arianne Vance, Mastaneh Sharafi, Kaelin C. Young, Michael D. Roberts
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
The purpose of this study was to validate the efficacy of a customized vitamin-mineral supplement on blood biomarkers in pre-menopausal females. Women (21–40 years old) who were apparently healthy were recruited from the local community (ClinicalTr
Externí odkaz:
https://doaj.org/article/b087cc4db38248d18872bdb121a4bc70
Autor:
Paul A. Roberson, C. Brooks Mobley, Matthew A. Romero, Cody T. Haun, Shelby C. Osburn, Petey W. Mumford, Christopher G. Vann, Rory A. Greer, Arny A. Ferrando, Michael D. Roberts
Publikováno v:
Frontiers in Nutrition, Vol 7 (2021)
Introduction: Amino acid transporters are essential for cellular amino acid transport and promoting protein synthesis. While previous literature has demonstrated the association of amino acid transporters and protein synthesis following acute resista
Externí odkaz:
https://doaj.org/article/e6dc9b04712c408c80f1f7fb1a5df520
Autor:
Matthew A. Romero, Petey W. Mumford, Paul A. Roberson, Shelby C. Osburn, Kaelin C. Young, John M. Sedivy, Michael D. Roberts
Publikováno v:
Exercise and sport sciences reviews. 50(4)
Retrotransposons are gene segments that proliferate in the genome, and the Long INterspersed Element 1 (LINE-1 or L1) retrotransposon is active in humans. Although older mammals show enhanced skeletal muscle L1 expression, exercise generally reverses
Autor:
Morgan A. Smith, Casey L. Sexton, Kristen A. Smith, Shelby C. Osburn, Joshua S. Godwin, Jonathan P. Beausejour, Bradley A. Ruple, Michael D. Goodlett, Joseph L. Edison, Andrew D. Fruge, Austin T. Robinson, L. Bruce Gladden, Kaelin C. Young, Michael D. Roberts
Publikováno v:
Journal of Applied Physiology. 134:491-507
This study continues to delineate muscle biology differences between lower and higher responders to resistance training and is unique in that a female population was interrogated. As has been reported in prior studies, increases in satellite cell num