Zobrazeno 1 - 10
of 42
pro vyhledávání: '"C. O. S. Savage"'
Autor:
A. R. Exley, Caroline Gordon, B. A. Janssen, George D. Kitas, Raashid Luqmani, David Carruthers, P. A. Bacon, C. O. S. Savage
Publikováno v:
Scopus-Elsevier
Because death after acute systemic vasculitis is now uncommon, alternative measures of outcome are required. A significant component of patient morbidity is disease-related damage, which can be quantified by the Vasculitis Damage Index (64 items in 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551d397e5ed92c39225a25cd9feaee80
https://ora.ox.ac.uk/objects/uuid:232ce3d3-bbb5-4ebb-b015-f4c0ee180d97
https://ora.ox.ac.uk/objects/uuid:232ce3d3-bbb5-4ebb-b015-f4c0ee180d97
Autor:
Michel Goldman, Laurence Noel, L. Moulonguet-Doleris, E. Dechelette, J. M. Pochet, C. O. S. Savage, Christopher Martin Lockwood, Yves Pirson, J. P. Grünfeld, G. Bobrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb6e6c734dcb9ec169f3a6b3ecbcfc2f
https://doi.org/10.1159/000418630
https://doi.org/10.1159/000418630
Autor:
Alexander J. Howie, J Lepenies, Paul Cockwell, Daniel Zehnder, R L Bates, Marcus Quinkler, Kevin S. Eardley, C. O. S. Savage, Dwomoa Adu
Publikováno v:
Kidney International. 69(7):1189-1197
Glomerular-derived proteins may activate tubular cells to express the macrophage-directed chemokine monocyte chemoattractant protein-1 (MCP-1/CCL2). Macrophages at interstitial sites have a central role in directing renal scarring. We have prospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e43d6b744658cf2d12f3f736b086ed
Autor:
Royston Jefferis, Mark J. G. Holland, Margaret Goodall, D. Adu, Peter Hewins, C. O. S. Savage
Publikováno v:
Clinical and Experimental Immunology. 138:183-192
SUMMARY A characteristic feature of Wegener's granulomatosis is the presence of antineutrophil cytoplasm antibodies (ANCA) to proteinase 3 (PR3). In vitro, ANCA activate neutrophils by co-ligating PR3 and FcγRIIa/IIIb receptors. ANCA are predominant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00321143c16fdb2ad2f4f79f0debc2a6
https://doi.org/10.1111/j.1365-2249.2004.02566.x
https://doi.org/10.1111/j.1365-2249.2004.02566.x
Autor:
Lorraine Harper, N. Takahashi, T. Okumoto, K. Takada, Koichi Kato, D. Adu, Anne Ben-Smith, Royston Jefferis, Mark J. G. Holland, C. O. S. Savage
Publikováno v:
Clinical and Experimental Immunology. 129:183-190
SUMMARYThe triad of small vessel vasculitides (SVV) comprise Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and Churg–Strauss syndrome (CS). All three are associated with presence of circulating IgG antineutrophil cytoplasm antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ec6d3ca4b20305aba1bcb3c7f93bd8
https://doi.org/10.1046/j.1365-2249.2002.01864.x
https://doi.org/10.1046/j.1365-2249.2002.01864.x
Publikováno v:
Rheumatology. 41:274-278
Neutrophils when activated generate a respiratory burst which has been implicated in the pathogenesis of primary systemic vasculitis. Neutrophils from patients with vasculitis have a greater respiratory burst than normal healthy donors. The aim of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee4f307217c6680dbb98ad7f6f2e027
https://doi.org/10.1093/rheumatology/41.3.274
https://doi.org/10.1093/rheumatology/41.3.274
Publikováno v:
Clinical and Experimental Immunology. 125:332-339
SummaryWegener's granulomatosis initially affects upper respiratory tract organs including the nasal mucosa in more than 90% of patients. The inflammation is typically granulomatous with associated vasculitis. T lymphocytes are usually a prominent co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7230a3ccfd77c9ac939392654a6d6a6b
https://doi.org/10.1046/j.1365-2249.2001.125002332.x
https://doi.org/10.1046/j.1365-2249.2001.125002332.x
Publikováno v:
Arthritis & Rheumatism. 44:921-930
OBJECTIVE Wegener's granulomatosis (WG) and microscopic polyangiitis (MPA) have been reported to be pathologically and clinically different. The aim of this study was to assess whether these differences could be explained by differing abilities of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb2dbf72b4ef520226df06d194ecd8de
https://doi.org/10.1002/1529-0131(200104)44:4<921::aid-anr149>3.0.co
https://doi.org/10.1002/1529-0131(200104)44:4<921::aid-anr149>3.0.co
Publikováno v:
Clinical and Experimental Immunology. 119:574-577
SUMMARY Neutrophils constitutively express FcγRIIa and FcγRIIIb receptors. Both receptors exhibit allelic variants which have different quantitative functional capacities: the biallelic FcγRIIa-R131 and -H131 alleles, and the neutrophil antigen (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658b2c179901706d1a9e5ce58237f58f
https://doi.org/10.1046/j.1365-2249.2000.01182.x
https://doi.org/10.1046/j.1365-2249.2000.01182.x