Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C. O. S. Sorzano"'
Autor:
D. Herreros, R. R. Lederman, J. M. Krieger, A. Jiménez-Moreno, M. Martínez, D. Myška, D. Strelak, J. Filipovic, C. O. S. Sorzano, J. M. Carazo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Conformational heterogeneity is key to understand how macromolecular function and structure converge. Here, the authors propose an algorithm designed to estimate structural landscapes directly from Cryo-EM particle images.
Externí odkaz:
https://doaj.org/article/4d28705ddb804b1c8cd8aed52e694f82
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Single Particle Analysis using cryo-electron microscopy is a structural biology technique aimed at capturing the three-dimensional (3D) conformation of biological macromolecules. Projection images used to construct the 3D density map are cha
Externí odkaz:
https://doaj.org/article/208ac4f5b9214c67b19c4936d2209615
Autor:
C. O. S. Sorzano, J. L. Vilas, E. Ramírez-Aportela, J. Krieger, D. del Hoyo, D. Herreros, E. Fernandez-Giménez, D. Marchán, J. R. Macías, I. Sánchez, L. del Caño, Y. Fonseca-Reyna, P. Conesa, A. García-Mena, J. Burguet, J. García Condado, J. Méndez García, M. Martínez, A. Muñoz-Barrutia, R. Marabini, J. Vargas, J. M. Carazo
Publikováno v:
E-Prints Complutense. Archivo Institucional de la UCM
instname
Faraday Discussions
instname
Faraday Discussions
Documento escrito por un elevado número de autores/as, solo se referencia el/la que aparece en primer lugar y los/as autores/as pertenecientes a la UC3M. Correction: The authors regret the omission of one of the authors, Federico de Isidro Gómez, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c7adadc84476db493cb22fed53b8ab
https://doi.org/10.1039/d2fd00059h
https://doi.org/10.1039/d2fd00059h
Publikováno v:
Pharmaceutical research.
The first-order absorption is a common model used in Pharmacokinetics. The absorption of some drugs follows carrier mediated transport. It has been proposed that the amount of drug available may saturate the transport mechanism resulting in an absorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::46bff1f8edbf9a5c9d3fc8be60c042ce
https://pubmed.ncbi.nlm.nih.gov/36543972
https://pubmed.ncbi.nlm.nih.gov/36543972
Autor:
C O S, Sorzano, J M, Carazo
Publikováno v:
Journal of structural biology. 214(3)
Cryo-Electron Microscopy (CryoEM) is currently a well-established method to elucidate a biological macromolecule's three-dimensional (3D) structure. Its success is due to technological and methodological advances in several fronts: sample preparation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b89166f4dde2e36399a58ed4c5185ead
https://pubmed.ncbi.nlm.nih.gov/35568276
https://pubmed.ncbi.nlm.nih.gov/35568276
Publikováno v:
Pharmaceutical research. 38(7)
Biopharmaceutics examines the interrelationship of the drug's physical/chemical properties, the dosage form (drug product) in which the drug is given, and the administration route on the rate and extent of sys- temic drug absorption. Pharmacokinetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8f9d87438c0fdcd5aea84bbf357721d
https://pubmed.ncbi.nlm.nih.gov/34160753
https://pubmed.ncbi.nlm.nih.gov/34160753
Publikováno v:
Journal of Molecular Biology. 434:167556
Computational approaches for predicting protein-protein interfaces are extremely useful for understanding and modelling the quaternary structure of protein assemblies. In particular, partner-specific binding site prediction methods allow delineating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f7a5feb150a28c21712072156737b2
https://doi.org/10.1016/j.jmb.2022.167556
https://doi.org/10.1016/j.jmb.2022.167556
Publikováno v:
Pharmaceutical research. 38(4)
The connection between pharmacokinetic models and system theory has been established for a long time. In this approach, the drug concentration is seen as the output of a system whose input is the drug administered at different times. In this article
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::deda8bcde524d1b1c323cd97d6be37c9
https://pubmed.ncbi.nlm.nih.gov/33751326
https://pubmed.ncbi.nlm.nih.gov/33751326
Autor:
M, Martínez, A, Jiménez-Moreno, D, Maluenda, E, Ramírez-Aportela, R, Melero, A, Cuervo, P, Conesa, L, Del Caño, Y C, Fonseca, R, Sánchez-García, D, Strelak, J J, Conesa, E, Fernández-Giménez, F, de Isidro, C O S, Sorzano, J M, Carazo, R, Marabini
Publikováno v:
Journal of chemical information and modeling. 60(5)
Advances in cryo-electron microscopy (cryo-EM) have made it possible to obtain structures of large biological macromolecules at near-atomic resolution. This "resolution revolution" has encouraged the use and development of modeling tools able to prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3279fbd4046ee741ca8b76d0d605787
https://pubmed.ncbi.nlm.nih.gov/31994878
https://pubmed.ncbi.nlm.nih.gov/31994878
Publikováno v:
Pattern Recognition. 39:1205-1213
In this work we discuss an improvement of the image-denoising wavelet-based method presented by Bijaoui [Wavelets, Gaussian mixtures and Wiener filtering, Signal Process. 82 (2002) 709-712]. We show that the parameter estimation step can be replaced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23bf6129f4d704c3dc6b5227fea7a045
https://doi.org/10.1016/j.patcog.2005.12.009
https://doi.org/10.1016/j.patcog.2005.12.009