Zobrazeno 1 - 10
of 12
pro vyhledávání: '"C. O. Hanemann"'
Autor:
L, Provenzano, Y, Ryan, D A, Hilton, J, Lyons-Rimmer, F, Dave, E A, Maze, C L, Adams, R, Rigby-Jones, S, Ammoun, C O, Hanemann
Publikováno v:
Oncogene. 36(44)
Loss of function mutations in the neurofibromatosis Type 2 (NF2) gene, coding for a tumour suppressor, Merlin, cause multiple tumours of the nervous system such as schwannomas, meningiomas and ependymomas. These tumours may occur sporadically or as p
Publikováno v:
Neuropathology and applied neurobiology. 38(6)
Δ⁹-tetrahydrocannabinol (Δ⁹-THC) is neuroprotective in models of Parkinson's disease (PD). Although CB1 receptors are increased within the basal ganglia of PD patients and animal models, current evidence suggests a role for CB1 receptor-indepen
Publikováno v:
Der Nervenarzt. 78(4)
Central core myopathy is a nonprogressive or only slowly progressive congenital muscle disease. In most cases, symptoms begin in childhood, but rare cases with adult onset are described. Regardless of its high variability, the clinical hallmarks are
Publikováno v:
Journal of neuroscience research. 61(5)
Neurofibromas are benign tumors arising from the peripheral nerve sheath and are a typical finding in neurofibromatosis type 1 (NF1). Schwann cells are the predominant cell type in neurofibromas and thus are supposed to play a major role in the patho
Autor:
M, Kamleiter, C O, Hanemann, L, Kluwe, C, Rosenbaum, S, Wosch, V F, Mautner, H W, Müller, P, Grafe
Publikováno v:
Glia. 24(3)
Previous experimental observations indicate that inhibition of voltage-dependent K+ currents suppresses proliferation of normal Schwann cells. In the present study we tested the opposite relationship, i.e., whether Schwann cells from tumors with abno
Publikováno v:
Musclenerve. 21(11)
This study examined major histocompatibility complex (MHC) class II expression and macrophage infiltration in sural nerve biopsies from patients with genetically proven Charcot-Marie-Tooth (CMT) 1A and 1B and hereditary neuropathy with liability to p
Publikováno v:
Glia. 23(2)
A duplication of the gene for myelin protein PMP22 is by far the most common cause of the hereditary demyelinating neuropathy CMT1A. A role for PMP22 in cell growth in addition to its function as a myelin protein has been suggested because PMP22 is h
Publikováno v:
Glia. 21(3)
Previous studies have shown that Schwann cell implantation offers a potential therapeutic approach to a variety of neurodegenerative disorders and traumatic injuries. In a clinically relevant paradigm, however, the implantation of autologous Schwann
Autor:
R, Korinthenberg, M, Sauer, U P, Ketelsen, C O, Hanemann, G, Stoll, M, Graf, A, Baborie, B, Volk, B, Wirth, S, Rudnik-Schöneborn, K, Zerres
Publikováno v:
Annals of neurology. 42(3)
Three newborn siblings presented with generalized weakness, asphyxia, facial diplegia, and external ophthalmoplegia. Electrophysiological testing showed inexcitability of motor and sensory nerves and myographic signs of denervation. Nerve biopsies an
Autor:
H W, Müller, U, Suter, C, Van Broeckhoven, C O, Hanemann, E, Nelis, V, Timmerman, S, Sancho, L, Barrio, P, Bolhuis, R, Dermietzel, M, Frank, A, Gabreëls-Festen, C, Gillen, N, Haites, G, Levi, E, Mariman, R, Martini, K, Nave, B, Rautenstrauss, M, Schachner, A, Schenone, C, Schneider, M, Schröder, K, Willecke, O, Haneman
Publikováno v:
Neurobiology of disease. 4(3-4)
The First Workshop of the European Consortium on Charcot-Marie-Tooth (CMT) disease brought together neuroscientists, molecular and cell biologists, neuropathologists, neurologists, and geneticists with a common interest in the understanding of the fu