Zobrazeno 1 - 10
of 102
pro vyhledávání: '"C. Newsome"'
Autor:
Rachel C. Newsome, Raad Z. Gharaibeh, Christine M. Pierce, Wildson Vieira da Silva, Shirlene Paul, Stephanie R. Hogue, Qin Yu, Scott Antonia, Jose R. Conejo-Garcia, Lary A. Robinson, Christian Jobin
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background Recent studies show that human gut microbial composition can determine whether a patient is a responder or non-responder to immunotherapy but have not identified a common microbial signal shared by responding patients. The functio
Externí odkaz:
https://doaj.org/article/91a0ce6cc50b4f098348471265ee7dcd
Autor:
Qin Yu, Rachel C. Newsome, Mark Beveridge, Maria C. Hernandez, Raad Z. Gharaibeh, Christian Jobin, Ryan M. Thomas
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Preclinical data demonstrate that the gut microbiota can promote pancreatic ductal adenocarcinoma (PDAC), but mechanisms remain unclear. We hypothesized that intestinal microbiota alters anti-tumor innate immunity response to facilitate PDAC progress
Externí odkaz:
https://doaj.org/article/2858803b71ee4d7daa38553db53e6d16
Autor:
Rachel C. Newsome, Josee Gauthier, Maria C. Hernandez, George E. Abraham, Tanya O. Robinson, Haley B. Williams, Meredith Sloan, Anna Owings, Hannah Laird, Taylor Christian, Yilianys Pride, Kenneth J. Wilson, Mohammad Hasan, Adam Parker, Michal Senitko, Sarah C. Glover, Raad Z. Gharaibeh, Christian Jobin
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
To investigate the relationship between intestinal microbiota and SARS-CoV-2-mediated pathogenicity in a United States, majority African American cohort. We prospectively collected fecal samples from 50 SARS-CoV-2 infected patients, 9 SARS-CoV-2 reco
Externí odkaz:
https://doaj.org/article/96685b2fdf614995a7d3332aa38157fb
Autor:
Sarah Tomkovich, Raad Z. Gharaibeh, Christine M. Dejea, Jillian L. Pope, Jinmai Jiang, Kathryn Winglee, Josee Gauthier, Rachel C. Newsome, Ye Yang, Anthony A. Fodor, Thomas D. Schmittgen, Cynthia L. Sears, Christian Jobin
Publikováno v:
mSystems, Vol 5, Iss 1 (2020)
ABSTRACT Disrupted interactions between host and intestinal bacteria are implicated in colorectal cancer (CRC) development. However, activities derived from these bacteria and their interplay with the host are unclear. Here, we examine this interplay
Externí odkaz:
https://doaj.org/article/562604d705874130859eedb5bee026db
Autor:
Rachel C Newsome, Qin Yu, Yoshitaka Murota, Derek Hood, Duy Nguyen, Ryan A Smolchek, Juan M Uruena, W Gregory Sawyer, Christian Jobin
Publikováno v:
Journal of Clinical and Translational Science, Vol 5, Pp 107-108 (2021)
ABSTRACT IMPACT: We are developing the 3D perfusion system for use with patient-derived bacteria to further characterize the mechanism behind bacterial-induced inflammation and cancer. OBJECTIVES/GOALS: We previously reported the adherent invasive E.
Externí odkaz:
https://doaj.org/article/0c7b2c0593f54c6f9afebcba436d0eb5
Autor:
Rachel C. Newsome, Joonseok Oh, Wenya Jian, Raad Z. Gharaibeh, Jason Crawford, Christian Jobin
Publikováno v:
Cancer Research. 83:1825-1825
Introduction: We previously showed that non-small cell lung cancer (NSCLC) patients that respond (R) to immune checkpoint blockade (ICB) have a different microbial community structure than non-responders (NR) pre-treatment (Genome Med 2022). Importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddbeb0bb8b931c34d4137065f60fceac
https://doi.org/10.1158/1538-7445.am2023-1825
https://doi.org/10.1158/1538-7445.am2023-1825
Publikováno v:
Nat Cancer
Intestinal inflammation and microbiota are two important components of colorectal cancer (CRC) etiology. However, it is not clear how tuning inflammation using clinically relevant anti-inflammatory treatment impacts microbiota or whether this consequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba6ee947e4e4ffb1757e3e0e1846c83
https://doi.org/10.1038/s43018-020-0078-7
https://doi.org/10.1038/s43018-020-0078-7
Publikováno v:
J Gastroenterol Hepatol
The gastrointestinal tract greatly contributes to global cancer burden and cancer-related deaths. The microbiota represents the population of microorganisms that live in and around the body, located primarily in the gastrointestinal tract. The microb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdcc4205eebc9f37cc5fba3c57fb76b5
https://europepmc.org/articles/PMC9922516/
https://europepmc.org/articles/PMC9922516/
Autor:
Rachel C. Newsome, Raad Z. Gharaibeh, Christine M. Pierce, Wildson Vieira da Silva, Shirlene Paul, Stephanie R. Hogue, Qin Yu, Scott Antonia, Jose R. Conejo-Garcia, Lary A. Robinson, Christian Jobin
Publikováno v:
Genome medicine. 14(1)
BackgroundRecent studies show that human gut microbial composition can determine whether a patient is a responder or non-responder to immunotherapy but have not identified a common microbial signal shared by responding patients. The functional relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b592a6a20deaf14329f4ea0b890c81
https://pubmed.ncbi.nlm.nih.gov/35346337
https://pubmed.ncbi.nlm.nih.gov/35346337
Autor:
Christian Jobin, Rachel C. Newsome
Publikováno v:
Clinical Chemistry. 67:463-465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a6e68d0197775cddd7f6d33942dbc2
https://doi.org/10.1093/clinchem/hvaa240
https://doi.org/10.1093/clinchem/hvaa240