Zobrazeno 1 - 10
of 41
pro vyhledávání: '"C. N. Scholfield"'
Autor:
Wimonchat Tangamornsuksan, Suphat Subongkot, C N Scholfield, Manupat Lohitnavy, Chuenjid Kongkaew
Publikováno v:
The pharmacogenomics journal. 20(1)
Associations between HLA-DRB1*07:01 and lapatinib-induced hepatotoxicity have been reported. To consolidate the results from all available reports in scientific databases, systematic review and meta-analysis techniques were used to quantify these ass
Publikováno v:
Microcirculation. 14:11-24
Control of ocular blood flow occurs predominantly at the level of the retinal and choroidal arterioles. The present article provides an overview of the Ca2 + handling mechanisms and plasmalemmal ion channels involved in the regulation of retinal and
Publikováno v:
Diabetologia. 46:1252-1259
To assess the effects of diabetes-induced activation of protein kinase C (PKC) on voltage-dependent and voltage-independent Ca2+ influx pathways in retinal microvascular smooth muscle cells.Cytosolic Ca2+ was estimated in freshly isolated rat retinal
Autor:
C. G. Gallagher, J. G. Noble, L. A. J. O’Neill, G. Boland, M. Quinn, M. A. Hollywood, I. D. Hill, C. Sweeney, C. M. O’Connor, B. F. Leek, M. D. Walker, R. G. O’Regan, D. C. Moriarty, A. J. Mackarel, S. O’Connor, K. M. O’Boyle, A. Moore, B. A. Gormley, A. McGuigan, J. J. O’Connor, P. McLoughlin, G. Saleshando, T. Robson, F. M. Keane, N. G. McHale, C. S. Downes, C. E. Herron, C. R. Barnett, H. R. Harty, S. R. McKeown, S. Ryan, S. M. McDonough, A. E. Dusoir, C. N. Scholfield, G. O’Cuinn, E. O’Loinsigh, E. M. Dunne, D. M. Cannon, M. McGuire, K. M. Lagan, S. D. Moore, D. M. Walsh, A. F. L. Cramp, W. T. McNicholas, A. S. Lowe, P. P. Corkery, K. D. McCloskey, J. M. Allen, P. D. Glasgow, D. Cox, C. Hutchinson, D. G. Hirst, T. Quinn, P. Nolan, E. Kilbride, G. McBean, A. K. Keenan, T. M. Curtis, V. C. Cullen, D. A. Hurley, S. Wilson, C. R. Clarke, G. D. Baxter, D. Hirst, H. P. Frizelle, A. Bradford, J. P. Ryan, B. P. Curran, S. W. Kerrigan, A. W. Baird, B. M. Hannigan, O. Carroll, D. J. Fitzerald, K. D. Thornbury, P. J. Magee, G. P. Sergeant, R. Humphrey
Publikováno v:
Irish Journal of Medical Science. 168:286-297
Publikováno v:
British journal of pharmacology. 168(7)
Ca(2+) imaging reveals subcellular Ca(2+) sparks and global Ca(2+) waves/oscillations in vascular smooth muscle. It is well established that Ca(2+) sparks can relax arteries, but we have previously reported that sparks can summate to generate Ca(2+)
Autor:
C. N. Scholfield, Tim M. Curtis
Publikováno v:
Diabetes/metabolism research and reviews. 20(1)
Diabetic retinopathy is one of the most common complications of diabetes and is a major cause of new blindness in the working-age population of developed countries. While the exact pathogenic basis of this condition remains ill defined, it is clear t
Autor:
T M, Curtis, C N, Scholfield
Publikováno v:
Investigative ophthalmologyvisual science. 41(8)
To characterize the effects of endothelin (ET)-1 on the Ca2+-activated Cl- conductance of choroidal arteriolar smooth muscle.Microvascular smooth muscle cells were enzymatically isolated from choroidal arterioles from the eyes of freshly killed rabbi
Autor:
Tim M. Curtis, C N Scholfield
Publikováno v:
Microvascular research. 59(2)
Rat retinae were dissociated to yield intact microvessels 7 to 42 microm in diameter. These were loaded with fura-2 AM and single fragments anchored down in a recording bath. Intracellular Ca(2+) levels from 20- to 30-microm sections of vessel were e
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 286(2)
The purpose of this study was to establish whether specific receptor subtypes are responsible for mediating the effects of endothelin-1 (ET-1) and endothelin-3 (ET-3) on the L-type calcium current (ICa) using a number of receptor-selective antagonist
Autor:
J. G. McGeown, Tom A. Gardiner, N. Wall, M. Convery, Tim M. Curtis, Jennine Dawicki, C. N. Scholfield, Alan W. Stitt
Publikováno v:
Microcirculation. 11:541-542