Zobrazeno 1 - 10
of 33
pro vyhledávání: '"C. Ming Tse"'
Type 1 diabetes human enteroid studies reveal major changes in the intestinal epithelial compartment
Autor:
Vishwesh Bharadiya, Yan Rong, Zixin Zhang, Ruxian Lin, Anthony Lawrence Guerrerio, C. Ming Tse, Mark Donowitz, Varsha Singh
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Lack of understanding of the pathophysiology of gastrointestinal (GI) complications in type 1 diabetes (T1D), including altered intestinal transcriptomes and protein expression represents a major gap in the management of these patients. Huma
Externí odkaz:
https://doaj.org/article/c2af854e08724404bab116939ff929f1
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8273 (2023)
Cholesterol-rich membrane domains, also called lipid rafts (LRs), are specialized membrane domains that provide a platform for intracellular signal transduction. Membrane proteins often cluster in LRs that further aggregate into larger platform-like
Externí odkaz:
https://doaj.org/article/a2bc4e0a41584cdda63e811f0eb539d7
Autor:
C. Ming Tse, Julie G. In, Jianyi Yin, Mark Donowitz, Michele Doucet, Jennifer Foulke-Abel, Fernando Ruiz-Perez, James P. Nataro, Nicholas C. Zachos, James B. Kaper, Olga Kovbasnjuk
Publikováno v:
Toxins, Vol 10, Iss 9, p 351 (2018)
One of the characteristic manifestations of Shiga-toxin-producing Escherichia coli (E. coli) infection in humans, including EHEC and Enteroaggregative E. coli O104:H4, is watery diarrhea. However, neither Shiga toxin nor numerous components of the ty
Externí odkaz:
https://doaj.org/article/381e15c12afc48dcbaeddf0037588a7d
Autor:
Subhash Kulkarni, Kelli Johnson, Mark Donowitz, C. Ming Tse, Rafiquel Sarker, Pankaj J. Pasricha, Julie In
Publikováno v:
Gastroenterology. 160:S-373
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d35b92fbfb7c94fcab6fb61f86f4f25
https://doi.org/10.1016/s0016-5085(21)01605-x
https://doi.org/10.1016/s0016-5085(21)01605-x
Autor:
Hannah J. Vaughan, Ruxian Lin, Nicholas C. Zachos, C. Ming Tse, Rafiquel Sarker, Jordan J. Green, Mark Donowitz
Publikováno v:
Gastroenterology. 160:S-63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b22bc834b44c85ca3aad2c5ae87cba8
https://doi.org/10.1016/s0016-5085(21)00894-5
https://doi.org/10.1016/s0016-5085(21)00894-5
Autor:
Prateeti Sarker, Raghothama Chaerkady, Xuhang Li, Varsha Singh, Tian E. Chen, Rafiquel Sarker, Jianyi Yin, Mark Donowitz, C. Ming Tse, Jianbo Yang
Publikováno v:
Biochemical Journal
The microvillar localization of Na+-H+ exchanger regulatory factor (NHERF)1/2 requires not only ezrin, radixin and moesin (ERM)-binding domain (EBD) but also a newly defined ERM-binding regulatory sequence (EBRS) that modulates NHERF1/2–ezrin bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e8e234d3db54341bcc17fe9f6446c1
https://doi.org/10.1042/bj20150238
https://doi.org/10.1042/bj20150238
Autor:
Rafiquel Sarker, Mark Donowitz, Tian E. Chen, Molee Chakraborty, Boyoung Cha, C. Ming Tse, Xinjun Cindy Zhu, John R. Horton
Publikováno v:
American Journal of Physiology-Cell Physiology. 308:C758-C766
Genetic determinants appear to play a role in susceptibility to chronic diarrhea, but the genetic abnormalities involved have only been identified in a few conditions. The Na+/H+exchanger 3 (NHE3) accounts for a large fraction of physiologic intestin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73a7dec20c76ca2eb1ea6945955eee1
https://doi.org/10.1152/ajpcell.00421.2014
https://doi.org/10.1152/ajpcell.00421.2014
Autor:
Hetal S. Kocinsky, Peter S. Aronson, Jianbo Yang, Hugo R. de Jonge, Rakhilya Murtazina, Robert N. Cole, Mark Donowitz, Boyoung Cha, C. Ming Tse, Tian-e Chen, Rafiquel Sarker, Varsha Singh
Publikováno v:
Journal of Biological Chemistry. 290:1952-1965
The epithelial brush-border Na+/H+ exchanger NHE3 is acutely inhibited by cGKII/cGMP, but how cGKII inhibits NHE3 is unknown. This study tested the hypothesis that cGMP inhibits NHE3 by phosphorylating it and altering its membrane trafficking. Studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3429e9078ef102aa732577cb54fe972f
https://doi.org/10.1074/jbc.m114.590174
https://doi.org/10.1074/jbc.m114.590174
Autor:
Daniel M. Raben, C. Ming Tse, Boyoung Cha, Jianbo Yang, Rafiquel Sarker, Olga Kovbasnjuk, Tian-e Chen, Mark Donowitz
Publikováno v:
American Journal of Physiology-Cell Physiology. 307:C55-C65
The Na+/H+ exchanger 3 (NHE3) is a brush border (BB) Na+/H+ antiporter that accounts for the majority of physiologic small intestinal and renal Na+ absorption. It is regulated physiologically and in disease via changes in endocytosis/exocytosis. Para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115ba90fefaa2dbd7e61dd90862d0092
https://doi.org/10.1152/ajpcell.00045.2014
https://doi.org/10.1152/ajpcell.00045.2014
Autor:
Lishou Xiong, Shi Jin, Varsha Singh, Nicholas C. Zachos, Rafiquel Sarker, Xuhang Li, Mark Donowitz, Tian E. Chen, C. Ming Tse, Jianbo Yang, Boyoung Cha
Publikováno v:
Journal of Biological Chemistry. 289:20039-20053
NHERF1, NHERF2, and NHERF3 belong to the NHERF (Na(+)/H(+) exchanger regulatory factor) family of PSD-95/Discs-large/ZO-1 (PDZ) scaffolding proteins. Individually, each NHERF protein has been shown to be involved in the regulation of multiple recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4c5816dbea685feb15f31fe6139943
https://doi.org/10.1074/jbc.m114.562413
https://doi.org/10.1074/jbc.m114.562413