Zobrazeno 1 - 10
of 14
pro vyhledávání: '"C. Michael Moriarty"'
Publikováno v:
International journal of toxicology. 21(2)
The purpose of this study was to characterize the effects of chronic lead exposure on growth hormone and insulin-like growth factor-1 status in growing male rats. Pituitary growth hormone content, episodic growth hormone release, plasma insulin-like
Autor:
Lisa M. White, Yuen-Sum Lau, Anna Marie Camoratto, Glenn O. Ware, Wallace D. Berry, C. Michael Moriarty
Publikováno v:
Toxicology. 83(1-3)
This study was undertaken to examine the effect of exposure to low level lead on growth and growth hormone (GH) release. Female pups exposed to lead beginning in utero were smaller than controls on postnatal day 7 (P = 0.06). There was no correspondi
Autor:
C. Michael Moriarty
Publikováno v:
Life Sciences. 23:185-194
It is now accepted by most investigators that the initial action of most peptide hormones involves an interaction with a specific receptor on (or in) the plasma membrane of the target cell. A cascade of intracellular events results and culminates in
Publikováno v:
Endocrinology. 96:1419-1425
Tissue levels of bioactive and immunoactive ACTH were measured in both the anterior and neuro-intermediate lobes of the rat pituitary. Similar concentrations of bioactive (65 ng/mg) and immunoactive (83 ng/mg) ACTH were found in the anterior lobes co
Publikováno v:
Life Sciences. 23:2073-2078
While exploring the interaction between thyrotropin releasing hormone (TRH) and normal rat anterior pituitary cells in monolayer culture we observed that cells dissociated with the use of trypsin did not respond to TRH with an increase in either TSH
Publikováno v:
Endocrinology. 96:1426-1436
The purpose of this study was to determine if there were ultrastructural and immunocytochemical changes in intermediate lobe cells following stress. We found marked cytological changes in intermediate lobe cells after 30 min of stress with a buzzer a
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 219:463-470
Unidirectional Na+ and Cl− fluxes across 15–18-day chick chorioallantoic membranes were determined in vitro using the short-circuit technique of Ussing and Zerahn 6. In the absence of an electrochemical gradient across the membrane, the observati
Autor:
C. Michael Moriarty, Jerry L. Fischer
Publikováno v:
Endocrinology. 100(4)
The purpose of this study was to identify agents capable of regulating the release of biologically active ACTH from the isolated neuro-intermediate lobe of the rat pituitary. Agents found to be potent secretagogues included acetylcholine (100 mug/ml)
Publikováno v:
Cell and Tissue Research. 220
In an attempt to assign morphologic identities to previously distinguished functional calcium compartments in the anterior pituitary of the rat, we employed the potassium pyroantimonate technique for cation localization. Tissues were incubated for 1
Publikováno v:
Endocrinology. 102(2)
Rat anterior pituitary cells were dissociated and subjected to 4 h of unit gravity sedimentation. Eighty-five 8-ml fractions were collected, and nine pooled fractions were placed in monolayer culture for 1 week. The attached cells were immunocytochem