Zobrazeno 1 - 10
of 12
pro vyhledávání: '"C. Michael Lin"'
Autor:
Leaf Huang, William Y. Kim, Shihao Hu, Weiyan Yin, Lina Liu, Yuhua Wang, Cong Luo, C. Michael Lin, Qi Liu, Lei Miao
Supplementary material and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366160582ddbeca62cd50680aaa94265
https://doi.org/10.1158/0008-5472.22415435
https://doi.org/10.1158/0008-5472.22415435
Autor:
Leaf Huang, William Y. Kim, Shihao Hu, Weiyan Yin, Lina Liu, Yuhua Wang, Cong Luo, C. Michael Lin, Qi Liu, Lei Miao
Supplementary Table S1. Antibodies Used in the Study Supplementary Table S2. Characterization of LPD NPs Supplementary Table S3. Primers Used in the Study Supplementary Table S4. Blood Chemistry after Treatments Supplementary Figure S1. Morphology an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c98ce1346bedb0d5760d8569f64fa4e
https://doi.org/10.1158/0008-5472.22415438.v1
https://doi.org/10.1158/0008-5472.22415438.v1
Autor:
Leaf Huang, William Y. Kim, Shihao Hu, Weiyan Yin, Lina Liu, Yuhua Wang, Cong Luo, C. Michael Lin, Qi Liu, Lei Miao
The off-target distribution of anticancer nanoparticles to fibroblasts creates a barrier to the effective treatment of desmoplastic tumors. However, we hypothesized that this nanoparticle detriment might be exploited to target the expression of secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52435c4f6508154f794f515fe545c310
https://doi.org/10.1158/0008-5472.c.6509294.v1
https://doi.org/10.1158/0008-5472.c.6509294.v1
Autor:
Shihao Hu, Lei Miao, C. Michael Lin, Weiyan Yin, Yuhua Wang, William Y. Kim, Lina Liu, Leaf Huang, Cong Luo, Qi Liu
Publikováno v:
Cancer Research. 77:719-731
The off-target distribution of anticancer nanoparticles to fibroblasts creates a barrier to the effective treatment of desmoplastic tumors. However, we hypothesized that this nanoparticle detriment might be exploited to target the expression of secre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2988245127e3cd2082f46d242d21eefc
https://doi.org/10.1158/0008-5472.can-16-0866
https://doi.org/10.1158/0008-5472.can-16-0866
Publikováno v:
Journal of Controlled Release. 244:63-73
Clinically, combined therapy of cisplatin (CDDP) and metformin is an effective treatment for non-small cell lung cancer (NSCLC). The success is attributed to synergistic effects between the two drugs. Therefore, we hypothesize that co-encapsulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca59729da31e886d2f39d8732ec3e0e
https://doi.org/10.1016/j.jconrel.2016.11.005
https://doi.org/10.1016/j.jconrel.2016.11.005
Autor:
Lu Zhang, Matthew I. Milowsky, Sara E. Wobker, Lei Miao, C. Michael Lin, William Y. Kim, Samuel K. Lai, Feifei Xu, Leaf Huang, Jay M. Newby, M. Gregory Forest
Publikováno v:
ACS Nano. 10:9243-9258
The binding site barrier (BSB) was originally proposed to describe the binding behavior of antibodies to cells peripheral to blood vessels, preventing their further penetration into the tumors. Yet, it is revisited herein to describe the intratumoral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452c04917815ca61277f39ef37839e44
https://doi.org/10.1021/acsnano.6b02776
https://doi.org/10.1021/acsnano.6b02776
Publikováno v:
Journal of Controlled Release. 219:192-204
Nanoparticle based delivery formulations have become a leading delivery strategy for cancer imaging and therapy. The success of nanoparticle-based therapy relies heavily on their ability to utilize the enhanced permeability and retention (EPR) effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f03c26caf15cc02909694b80992d13d6
https://doi.org/10.1016/j.jconrel.2015.08.017
https://doi.org/10.1016/j.jconrel.2015.08.017
Autor:
Yang Xiong, Naihan Chen, Lu Zhang, Yuhua Wang, William Y. Kim, Leaf Huang, Lei Miao, C. Michael Lin
Publikováno v:
Journal of Controlled Release. 217:27-41
The tumor microenvironment (TME) serves as a multidrug resistant center for tumors under the assault of chemotherapy and a physiological barrier against the penetration of therapeutic nanoparticles (NPs). Previous studies have indicated the ability f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57bdaaecda80a836e69b54276442412e
https://doi.org/10.1016/j.jconrel.2015.08.027
https://doi.org/10.1016/j.jconrel.2015.08.027
Nanoparticle drug formulations have been extensively investigated, developed, and in some cases, approved by the Food and Drug Administration (FDA). Synergistic combinations of drugs having distinct tumor-inhibiting mechanisms and non-overlapping tox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eca1500c3c84e464ac439f80c3c4035
https://europepmc.org/articles/PMC5591780/
https://europepmc.org/articles/PMC5591780/
Publikováno v:
ACS Nano
The tumor microenvironment plays an important role in the tumor's progression and metastasis. Therefore, successful alteration of this delicate setting against the tumor's favor can open a window for therapeutic efficacy. We have developed a modality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf1255336cb4d7103ed08ab810ba7c3
http://europepmc.org/articles/PMC4046782
http://europepmc.org/articles/PMC4046782