Zobrazeno 1 - 10
of 758
pro vyhledávání: '"C. Meredith"'
Autor:
Michael Maybin, Aditi M. Ranade, Ursula Schombel, Nicolas Gisch, Uwe Mamat, Timothy C. Meredith
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Polymyxins [colistin and polymyxin B (PMB)] comprise an important class of natural product lipopeptide antibiotics used to treat multidrug-resistant Gram-negative bacterial infections. These positively charged lipopeptides interact with lipo
Externí odkaz:
https://doaj.org/article/93209f08620b44d7839200c2088766f4
Autor:
Urszula Dougherty, Reba Mustafi, Hongyan Zhu, Xiaorong Zhu, Dilip Deb, Stephen C. Meredith, Fatma Ayaloglu-Butun, Michelle Fletcher, Arantxa Sanchez, Joel Pekow, Zifeng Deng, Nader Amini, Vani J Konda, Vijaya L. Rao, Atsushi Sakuraba, Akushika Kwesi, Sonia S Kupfer, Alessandro Fichera, Loren Joseph, John Hart, Fang He, Tong-Chuan He, Diana West-Szymanski, Yan Chun Li, Marc Bissonnette
Publikováno v:
Epigenetics, Vol 16, Iss 12, Pp 1317-1334 (2021)
Because ADAM17 promotes colonic tumorigenesis, we investigated potential miRNAs regulating ADAM17; and examined effects of diet and tumorigenesis on these miRNAs. We also examined pre-miRNA processing and tumour suppressor roles of several of these m
Externí odkaz:
https://doaj.org/article/acd55d7ef57b4fb5860f8bbd146ae130
Autor:
Kathryn P. Scherpelz, Songlin Wang, Peter Pytel, Rama S. Madhurapantula, Atul K. Srivastava, Joseph R. Sachleben, Joseph Orgel, Yoshitaka Ishii, Stephen C. Meredith
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Alzheimer’s disease is characterized by neuritic plaques, the main protein components of which are β-amyloid (Aβ) peptides deposited as β-sheet-rich amyloid fibrils. Cerebral Amyloid Angiopathy (CAA) consists of cerebrovascular deposits
Externí odkaz:
https://doaj.org/article/549a89f7338448fd9a222cd6a6278088
Publikováno v:
Atmospheric Chemistry and Physics, Vol 19, Pp 4741-4761 (2019)
The role of surfactants in governing water interactions of atmospheric aerosols has been a recurring topic in cloud microphysics for more than two decades. Studies of detailed surface thermodynamics are limited by the availability of aerosol samples
Externí odkaz:
https://doaj.org/article/93adce049b554c0299f874e2308fa411
Autor:
John H. Gardiner, Gloria Komazin, Miki Matsuo, Kaitlin Cole, Friedrich Götz, Timothy C. Meredith
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Bacterial lipoproteins (Lpps) are a class of membrane-associated proteins universally distributed among all bacteria. A characteristic N-terminal cysteine residue that is variably acylated anchors C-terminal globular domains to the extracell
Externí odkaz:
https://doaj.org/article/0dc2e21b11354398ab1fff8f78158146
Autor:
Bruno P. Lima, Kelvin Kho, Brittany L. Nairn, Julia R. Davies, Gunnel Svensäter, Ruoqiong Chen, Amanda Steffes, Gerrit W. Vreeman, Timothy C. Meredith, Mark C. Herzberg
Publikováno v:
mSphere, Vol 4, Iss 6 (2019)
ABSTRACT Lipoteichoic acid (LTA) is an abundant polymer of the Gram-positive bacterial cell envelope and is essential for many species. Whereas the exact function of LTA has not been elucidated, loss of LTA in some species affects hydrophobicity, bio
Externí odkaz:
https://doaj.org/article/5dc7f64bae3c4a60aede78db657e9911
Autor:
Kathryn A Coe, Wonsik Lee, Madeleine C Stone, Gloria Komazin-Meredith, Timothy C Meredith, Yonatan H Grad, Suzanne Walker
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1007862 (2019)
Antibiotic-resistant Staphylococcus aureus remains a leading cause of antibiotic resistance-associated mortality in the United States. Given the reality of multi-drug resistant infections, it is imperative that we establish and maintain a pipeline of
Externí odkaz:
https://doaj.org/article/a3fcbfb5357d44ef956c36af3b3fe34d
Akademický článek
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Akademický článek
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Autor:
Jacob D. Muscato, Heidi G. Morris, Aaron Mychack, Mithila Rajagopal, Vadim Baidin, Anthony R. Hesser, Wonsik Lee, Kemal İnecik, Laura J. Wilson, Christina M. Kraml, Timothy C. Meredith, Suzanne Walker
Publikováno v:
Journal of the American Chemical Society. 144:3696-3705
Synthetic lethality occurs when inactivation of two genes is lethal but inactivation of either single gene is not. This phenomenon provides an opportunity for efficient compound discovery. Using differential growth screens, one can identify biologica