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Akademický článek

Rescuing historical weather observations improves quantification of severe windstorm risks

Autor: E. Hawkins, P. Brohan, S. N. Burgess, S. Burt, G. P. Compo, S. L. Gray, I. D. Haigh, H. Hersbach, K. Kuijjer, O. Martínez-Alvarado, C. McColl, A. P. Schurer, L. Slivinski, J. Williams

Publikováno v: Natural Hazards and Earth System Sciences, Vol 23, Pp 1465-1482 (2023)

Billions of historical climatological observations remain unavailable to science as they exist only on paper, stored in numerous archives around the world. The conversion of these data from paper to digital could transform our understanding of histor

Externí odkaz: https://doaj.org/article/17c3d58dbc6043e39077c2cca150ca65

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Supplemental Figure 4 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal

Autor: Joshua M. Stuart, Olena Morozova, David Haussler, Theodore C. Goldstein, Manu Chopra, Kyle Ellrott, Sofie R. Salama, Robert Baertsch, Alana S. Weinstein, Kiley Graim, Sahil Chopra, Duncan C. McColl, Teresa Swatloski, Adam M. Novak, Yulia Newton

Enrichment of Immune signaling in the integrated pan-cancer cluster. Different level of evidence support the association of the integrated pan-cancer cluster with an immune phenotype. (A) Enrichment of T- and B-cell signaling shown on the integrated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033f5c5991b186b598f5290a611e375a
https://doi.org/10.1158/0008-5472.22419030

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Supplemental Figure 1 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal

Supplemental Figure 1: RSS transformed correlations correct for platform-specific inflation biases. Maps produced from different molecular data types. Samples in the maps are colored by tissue of origin. (A) Similarity score distributions for every p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085d2f6da7a832b71d3d16cee91ed83a
https://doi.org/10.1158/0008-5472.22419039

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Supplemental Figure 2 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal

Molecular subtype visualization. Known biology recapitulated by the mRNA expression map. (A) BRCA molecular subtypes and their layout in the map. The map shows that tumors of the same molecular subtype tend to cluster together, with very little mixin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652ef3c77b81608a07222cd4d32daf0e
https://doi.org/10.1158/0008-5472.22419036.v1

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Data from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal

Vast amounts of molecular data are being collected on tumor samples, which provide unique opportunities for discovering trends within and between cancer subtypes. Such cross-cancer analyses require computational methods that enable intuitive and inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dd77e6e5ba3b3963f598ebcf0087e80
https://doi.org/10.1158/0008-5472.c.6510276.v1

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Supplemental Table 1 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal

Supplemental Table 1A: Differential expression scores used in the pan-cancer cluster GSEA analysis. These scores represent integrated t-statistic scores from the differential analysis within each tissue (see Supplemental Methods). Supplemental Table

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10adbc822be3f473f8bbd44f7a1e2f30
https://doi.org/10.1158/0008-5472.22419021

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Supplemental Figure 5 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal

Supplemental Figure 5: (A) Overview of the method to compute differential expression for samples in the integrated pan-cancer group vs. other samples in the TCGA cohort. Tissue composition imbalance was corrected for by performing t-tests within each

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566016d41de9ff9003bd513c850ee4c0
https://doi.org/10.1158/0008-5472.22419027

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Supplemental Figure 3 from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal

Tissue and molecular subtype distribution among the samples in the entire cohort (A-B), and in the pan-cancer cluster (C-D). The pie charts represent the number of samples from each tissue of origin in the entire cohort (A) and the integrated pan-can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596cbe6242368f6324caf8db6e3b6747
https://doi.org/10.1158/0008-5472.22419033

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