Zobrazeno 1 - 6
of 6
pro vyhledávání: '"C. Matthew Hope"'
Publikováno v:
eLife, Vol 7 (2018)
During development, transcriptional complexes at enhancers regulate gene expression in complex spatiotemporal patterns. To achieve robust expression without spurious activation, the affinity and specificity of transcription factor–DNA interactions
Externí odkaz:
https://doaj.org/article/f26c42e5de834b5897f0e554eed7eaed
Publikováno v:
Nucleic Acids Research
Ribosome profiling (also known as Ribo-seq) has become an important technique to investigate changes in translation across a wide variety of contexts. Ribo-seq data not only provides the abundance of ribosomes bound to transcripts, but also positiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db3ac694460786d530453e53127a289d
http://europepmc.org/articles/PMC7708064
http://europepmc.org/articles/PMC7708064
Publikováno v:
Biophysical Journal. 112:180-192
Transcription factors use both protein-DNA and protein-protein interactions to assemble appropriate complexes to regulate gene expression. Although most transcription factors operate as monomers or dimers, a few, including the E26 transformation-spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ef431c4dae6443d4e9612d27799a03
https://doi.org/10.1016/j.bpj.2016.11.901
https://doi.org/10.1016/j.bpj.2016.11.901
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
During development, transcriptional complexes at enhancers regulate gene expression in complex spatiotemporal patterns. To achieve robust expression without spurious activation, the affinity and specificity of transcription factor–DNA interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa649bb917351a51b60606df62dcb04f
http://europepmc.org/articles/PMC6226293
http://europepmc.org/articles/PMC6226293
Autor:
Yuan Lin, Michael Glotzer, Chloe Antoniou, Josiah P. Zayner, Tobin R. Sosnick, Eric L. Weiss, Elizabeth Wagner, Devin Strickland, C Matthew Hope
Publikováno v:
Nature methods
Light-inducible dimerization tags are engineered to rapidly recruit proteins to precise points in living yeast and mammalian cells. The affinities and response time of the interactions are tunable, and the authors used the system to activate cell sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab28bbeb5ed6ec13aa71bab6221be484
http://europepmc.org/articles/PMC3444151
http://europepmc.org/articles/PMC3444151