Zobrazeno 1 - 10
of 24
pro vyhledávání: '"C. Matthew Bradbury"'
Autor:
Marcus Bosenberg, Betsy Nelson, David P. Curley, Cara Hobbs, C. Matthew Bradbury, Sekhar Duraisamy, Viswanathan Muthusamy
Supplementary Figure S3 from Epigenetic Silencing of Novel Tumor Suppressors in Malignant Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a999769e87a192b780c81ae1d690ab9
https://doi.org/10.1158/0008-5472.22366682.v1
https://doi.org/10.1158/0008-5472.22366682.v1
Autor:
Marcus Bosenberg, Betsy Nelson, David P. Curley, Cara Hobbs, C. Matthew Bradbury, Sekhar Duraisamy, Viswanathan Muthusamy
Malignant melanoma is a common and frequently lethal disease. Current therapeutic interventions have little effect on survival, emphasizing the need for a better understanding of the genetic, epigenetic, and phenotypic changes in melanoma formation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f70d2a8e04e9c45673e087dc20a350d
https://doi.org/10.1158/0008-5472.c.6495245.v1
https://doi.org/10.1158/0008-5472.c.6495245.v1
Autor:
Marcus Bosenberg, Betsy Nelson, David P. Curley, Cara Hobbs, C. Matthew Bradbury, Sekhar Duraisamy, Viswanathan Muthusamy
Supplementary Table S2 from Epigenetic Silencing of Novel Tumor Suppressors in Malignant Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bc2723284d9d50d6550f0944f88d08
https://doi.org/10.1158/0008-5472.22366667
https://doi.org/10.1158/0008-5472.22366667
Autor:
David Gius, Andrew P. Feinberg, Jane B. Trepel, Sunmin Lee, Hengmi Cui, Wenqiang Yu, C. Matthew Bradbury, Allen S. Ho, Gil Bar-Sela, Kheem S. Bisht, Phuongmai Nguyen, Lei Huang, Lunching Sun
Supplementary Figures 1-4, Methods and Materials from DNA Methyltransferase 1 and 3B Activate BAG-1 Expression via Recruitment of CTCFL/BORIS and Modulation of Promoter Histone Methylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca86961361bd4c73125d9eabe134c62
https://doi.org/10.1158/0008-5472.22375622.v1
https://doi.org/10.1158/0008-5472.22375622.v1
Autor:
David Gius, Andrew P. Feinberg, Jane B. Trepel, Sunmin Lee, Hengmi Cui, Wenqiang Yu, C. Matthew Bradbury, Allen S. Ho, Gil Bar-Sela, Kheem S. Bisht, Phuongmai Nguyen, Lei Huang, Lunching Sun
In a previous genomic analysis, using somatic methyltransferase (DNMT) knockout cells, we showed that hypomethylation decreased the expression of as many genes as were observed to increase, suggesting a previously unknown mechanism for epigenetic reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813caa1a86837798300d46c06ce06de9
https://doi.org/10.1158/0008-5472.c.6497882
https://doi.org/10.1158/0008-5472.c.6497882
Publikováno v:
Clinics in plastic surgery. 48(4)
While primary treatment for melanoma consists of surgical resection and chemotherapeutics, radiation can be used as either definitive or adjuvant therapy in certain clinical scenarios. This chapter aims to explore the indications for primary definiti
Autor:
David Gius, Jane B. Trepel, Lunching Sun, Andrew P. Feinberg, Phuongmai Nguyen, Lei Huang, Kheem S. Bisht, Wenqiang Yu, Sunmin Lee, C. Matthew Bradbury, Allen S. Ho, Gil Bar-Sela, Hengmi Cui
Publikováno v:
Cancer Research. 68:2726-2735
In a previous genomic analysis, using somatic methyltransferase (DNMT) knockout cells, we showed that hypomethylation decreased the expression of as many genes as were observed to increase, suggesting a previously unknown mechanism for epigenetic reg
Autor:
J. Daniel Pennington, Kheem S. Bisht, Weiling Zhao, Tony J. C. Wang, Gil Bar-Sela, C. Matthew Bradbury, Lei Huang, David Gius, Michael E. Robbins, Phuongmai Nguyen, Mark Mishra, Rania T. Awwad, Eric Y. Chuang, Lunching Sun, Zhijun Chen
Publikováno v:
Clinical Cancer Research. 12:3823-3830
Purpose: There is a growing awareness that radiation-induced normal tissue injury in late-responding organs, such as the brain, kidney, and lung, involves complex and dynamic responses between multiple cell types that not only lead to targeted cell d
Autor:
Dee Dee K. Smart, Lunching Sun, Kheem S. Bisht, Phuongmai Nguyen, Allen S. Ho, Rania T. Awwad, David Gius, C. Matthew Bradbury, Lei Huang
Publikováno v:
Cancer. 104:1789-1793
Tumor cell proliferation, de-differentiation, and progression depend on a complex combination of altered cell cycle regulation, excessive growth factor pathway activation, and decreased apoptosis. The understanding of these complex mechanisms should
Autor:
Lilie L Lin, Xinrong Ma, Douglas R. Spitz, Dhananjaya V. Kalvakolanu, Shervin Karimpour, Prabhat C. Goswami, David Gius, Junyang Lou, C. Matthew Bradbury, Stephanie Markovina, Junji Yodoi, Lucio Lagunas, Kiichi Hirota, Sreenivasu Karra, Luis M. Rene
Publikováno v:
Oncogene. 21:6317-6327
A recently identified class of signaling factors uses critical cysteine motif(s) that act as redox-sensitive 'sulfhydryl switches' to reversibly modulate specific signal transduction cascades regulating downstream proteins with similar redox-sensitiv