Zobrazeno 1 - 10
of 134
pro vyhledávání: '"C. Marcelo Aldaz"'
Autor:
Martin C. Abba, María Laura Fabre, Jaeho Lee, Pradeep Tatineni, Hyunsuk Kil, C. Marcelo Aldaz
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The long-non-coding HOX transcript antisense intergenic RNA (HOTAIR) was identified as significantly upregulated in breast ductal carcinoma in situ (DCIS). The aim of this study was to characterize the phenotypic effects and signaling pathways modula
Externí odkaz:
https://doaj.org/article/5594fe79e39c4b5ba772736ca4a05dd7
Autor:
Tabish Hussain, Hyunsuk Kil, Bharathi Hattiangady, Jaeho Lee, Maheedhar Kodali, Bing Shuai, Sahithi Attaluri, Yoko Takata, Jianjun Shen, Martin C. Abba, Ashok K. Shetty, C. Marcelo Aldaz
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 163-176 (2019)
The association of WW domain-containing oxidoreductase WWOX gene loss of function with central nervous system (CNS) related pathologies is well documented. These include spinocerebellar ataxia, epilepsy and mental retardation (SCAR12, OMIM: 614322) a
Externí odkaz:
https://doaj.org/article/b2b23f03ce6f4a2397a5ee27171f943e
Autor:
María Laura Fabre, Romina Canzoneri, Agustina Gurruchaga, Jaeho Lee, Pradeep Tatineni, Hyunsuk Kil, Ezequiel Lacunza, C. Marcelo Aldaz, Martín Carlos Abba
Publikováno v:
Cancers, Vol 14, Iss 12, p 2819 (2022)
Long non-coding RNAs are increasingly being recognized as cancer biomarkers in various malignancies, acting as either tumor suppressors or oncogenes. The long non-coding MALINC1 intergenic RNA was identified as significantly upregulated in breast duc
Externí odkaz:
https://doaj.org/article/a4e4a3d61fc84544b34b68711054b58a
Autor:
Dongju Park, Mehdi Gharghabi, Colleen R. Reczek, Rebecca Plow, Charles Yungvirt, C. Marcelo Aldaz, Kay Huebner
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3729 (2022)
Wwox-deficient human cells show elevated homologous recombination, leading to resistance to killing by double-strand break-inducing agents. Human Wwox binds to the Brca1 981-PPLF-984 Wwox-binding motif, likely blocking the pChk2 phosphorylation site
Externí odkaz:
https://doaj.org/article/cb7f36b8adc34394bccd8ce9ac2ad57e
Autor:
Athel Cornish-Bowden, David Rasnick, Henry H. Heng, Steven Horne, Batoul Abdallah, Guo Liu, Christine J. Ye, Mathew Bloomfield, Mark D. Vincent, C. Marcelo Aldaz, Jenny Karlsson, Anders Valind, Caroline Jansson, David Gisselsson, Jennifer A. Marshall Graves, Aleksei A. Stepanenko, Svitlana V. Andreieva, Kateryna V. Korets, Dmytro O. Mykytenko, Nataliya L. Huleyuk, Vladimir P. Baklaushev, Oksana A. Kovaleva, Vladimir P. Chekhonin, Yegor S. Vassetzky, Stanislav S. Avdieiev, Bjorn Bakker, Aaron S. Taudt, Mirjam E. Belderbos, David Porubsky, Diana C. J. Spierings, Tristan V. de Jong, Nancy Halsema, Hinke G. Kazemier, Karina Hoekstra-Wakker, Allan Bradley, Eveline S. J. M. de Bont, Anke van den Berg, Victor Guryev, Peter M. Lansdorp, Maria Colomé Tatché, Floris Foijer, Thomas Liehr, Nicolaas C. Baudoin, Joshua M. Nicholson, Kimberly Soto, Isabel Quintanilla, Jordi Camps, Daniela Cimini, M. Dürrbaum, N. Donnelly, V. Passerini, C. Kruse, B. Habermann, Z. Storchová, Daniele Mandrioli, Fiorella Belpoggi, Ellen K Silbergeld, Melissa J Perry, Rolf I. Skotheim, Marthe Løvf, Bjarne Johannessen, Andreas M. Hoff, Sen Zhao, Jonas M. SveeStrømme, Anita Sveen, Ragnhild A. Lothe, R. Hehlmann, A. Voskanyan, A. Fabarius, Alfred Böcking, Stefan Biesterfeld, Leonid Berynskyy, Christof Börgermann, Rainer Engers, Josef Dietz, A. Fritz, N. Sehgal, J. Vecerova, B. Stojkovicz, H. Ding, N. Page, C. Tye, S. Bhattacharya, J. Xu, G. Stein, J. Stein, R. Berezney, Xue Gong, Sarah Grasedieck, Julian Swoboda, Frank G. Rücker, Lars Bullinger, Jonathan R. Pollack, Fani-Marlen Roumelioti, Maria Chiourea, Christina Raftopoulou, Sarantis Gagos, Peter Duesberg, Mat Bloomfield, Sunyoung Hwang, Hans Tobias Gustafsson, Ciara O’Sullivan, Aracelli Acevedo-Colina, Xinhe Huang, Christian Klose, Andrej Schevchenko, Robert C. Dickson, Paola Cavaliere, Noah Dephoure, Eduardo M. Torres, Martha R. Stampfer, Lukas Vrba, Mark A. LaBarge, Bernard Futscher, James C. Garbe, Yi-Hong Zhou, Andrew L. Trinh, Michelle Digman
Publikováno v:
Molecular Cytogenetics, Vol 10, Iss S2, Pp 77-94 (2017)
Externí odkaz:
https://doaj.org/article/b6866d4289674f288bf6c946e8f882e4
Autor:
Kevin M. McBride, Hyunsuk Kil, Yunxiang Mu, Joshua B. Plummer, Jaeho Lee, Maciej J. Zelazowski, Manu Sebastian, Martin C. Abba, C. Marcelo Aldaz
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
WWOX (WW domain containing oxidoreductase) expression loss is common in various cancers and characteristic of poor prognosis. Deletions, translocations, and loss of expression affecting the WWOX gene are a common feature of various B cell neoplasms s
Externí odkaz:
https://doaj.org/article/e5fe1f8308c34c35a6c5898c7b8a631f
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
It has become clear from multiple studies that WWOX (WW domain-containing oxidoreductase) operates as a “non-classical” tumor suppressor of significant relevance in cancer progression. Additionally, WWOX has been recognized for its role in a much
Externí odkaz:
https://doaj.org/article/7c389174fe834a4d9937718a223d2de6
Autor:
C. Marcelo Aldaz, Tabish Hussain
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 8922 (2020)
The WWOX gene was initially discovered as a putative tumor suppressor. More recently, its association with multiple central nervous system (CNS) pathologies has been recognized. WWOX biallelic germline pathogenic variants have been implicated in spin
Externí odkaz:
https://doaj.org/article/8da10873c9a9467cadb57cd63b00d0e7
Autor:
Martin C. Abba, Romina Canzoneri, Agustina Gurruchaga, Jaeho Lee, Pradeep Tatineni, Hyunsuk Kil, Ezequiel Lacunza, C. Marcelo Aldaz
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7407 (2020)
Long intergenic non-protein coding RNA 885 (LINC00885) was identified as significantly upregulated in breast ductal carcinoma in situ (DCIS). The aim of this study was to characterize the phenotypic effects and signaling pathways modulated by LINC008
Externí odkaz:
https://doaj.org/article/173dff629d22479ebba42a9d98d74b08
Autor:
C. Marcelo Aldaz, Daniel Medina, Powel H. Brown, Reid P. Bissonnette, Jamal Hill, Frances S. Kittrell, Sally Gaddis, Carla C. Levy, Yuhui Hu, Martín C. Abba
Supplementary Materials 2 from Identification of Modulated Genes by Three Classes of Chemopreventive Agents at Preneoplastic Stages in a p53-Null Mouse Mammary Tumor Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48745c52949bf0bf820ef185a91ab79b
https://doi.org/10.1158/1940-6207.22523743.v1
https://doi.org/10.1158/1940-6207.22523743.v1