Zobrazeno 1 - 10
of 185
pro vyhledávání: '"C. Marcelo Aldaz"'
Autor:
Martin C. Abba, María Laura Fabre, Jaeho Lee, Pradeep Tatineni, Hyunsuk Kil, C. Marcelo Aldaz
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The long-non-coding HOX transcript antisense intergenic RNA (HOTAIR) was identified as significantly upregulated in breast ductal carcinoma in situ (DCIS). The aim of this study was to characterize the phenotypic effects and signaling pathways modula
Externí odkaz:
https://doaj.org/article/5594fe79e39c4b5ba772736ca4a05dd7
Autor:
Tabish Hussain, Hyunsuk Kil, Bharathi Hattiangady, Jaeho Lee, Maheedhar Kodali, Bing Shuai, Sahithi Attaluri, Yoko Takata, Jianjun Shen, Martin C. Abba, Ashok K. Shetty, C. Marcelo Aldaz
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 163-176 (2019)
The association of WW domain-containing oxidoreductase WWOX gene loss of function with central nervous system (CNS) related pathologies is well documented. These include spinocerebellar ataxia, epilepsy and mental retardation (SCAR12, OMIM: 614322) a
Externí odkaz:
https://doaj.org/article/b2b23f03ce6f4a2397a5ee27171f943e
Autor:
María Laura Fabre, Romina Canzoneri, Agustina Gurruchaga, Jaeho Lee, Pradeep Tatineni, Hyunsuk Kil, Ezequiel Lacunza, C. Marcelo Aldaz, Martín Carlos Abba
Publikováno v:
Cancers, Vol 14, Iss 12, p 2819 (2022)
Long non-coding RNAs are increasingly being recognized as cancer biomarkers in various malignancies, acting as either tumor suppressors or oncogenes. The long non-coding MALINC1 intergenic RNA was identified as significantly upregulated in breast duc
Externí odkaz:
https://doaj.org/article/a4e4a3d61fc84544b34b68711054b58a
Autor:
Dongju Park, Mehdi Gharghabi, Colleen R. Reczek, Rebecca Plow, Charles Yungvirt, C. Marcelo Aldaz, Kay Huebner
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3729 (2022)
Wwox-deficient human cells show elevated homologous recombination, leading to resistance to killing by double-strand break-inducing agents. Human Wwox binds to the Brca1 981-PPLF-984 Wwox-binding motif, likely blocking the pChk2 phosphorylation site
Externí odkaz:
https://doaj.org/article/cb7f36b8adc34394bccd8ce9ac2ad57e
Autor:
C. Marcelo Aldaz, Daniel Medina, Powel H. Brown, Reid P. Bissonnette, Jamal Hill, Frances S. Kittrell, Sally Gaddis, Carla C. Levy, Yuhui Hu, Martín C. Abba
Supplementary Materials 2 from Identification of Modulated Genes by Three Classes of Chemopreventive Agents at Preneoplastic Stages in a p53-Null Mouse Mammary Tumor Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48745c52949bf0bf820ef185a91ab79b
https://doi.org/10.1158/1940-6207.22523743.v1
https://doi.org/10.1158/1940-6207.22523743.v1
Autor:
Kornelia Polyak, Joe Gray, Catherine Wu, Joon Jeong, So Yeon Park, C. Marcelo Aldaz, Bojana Jovanović, Jennifer Eng, Guillaume Thibault, Young Hwan Chang, Koei Chin, Sachet A. Shukla, Carlos R. Gil Del Alcazar, Anne Trinh
S1. Overview of patient cohort. S2. Whole exome sequencing of matched DCISand IDC transition. S3. Mutationalprofiling of the DCIS-to-IDC transition. S4.Phenotypic immune properties of patient cohort. S5.Immune-related genomicchanges and neoantigen lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7edba2c92e3ebffa2d8110c7b4f0c5
https://doi.org/10.1158/1541-7786.22526628.v1
https://doi.org/10.1158/1541-7786.22526628.v1
Autor:
Kornelia Polyak, Joe Gray, Catherine Wu, Joon Jeong, So Yeon Park, C. Marcelo Aldaz, Bojana Jovanović, Jennifer Eng, Guillaume Thibault, Young Hwan Chang, Koei Chin, Sachet A. Shukla, Carlos R. Gil Del Alcazar, Anne Trinh
The drivers of ductal carcinoma in situ (DCIS) to invasive ductal carcinoma (IDC) transition are poorly understood. Here, we conducted an integrated genomic, transcriptomic, and whole-slide image analysis to evaluate changes in copy-number profiles,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4043beefe3b68d4bdf3955b02befc6cc
https://doi.org/10.1158/1541-7786.c.6545157.v1
https://doi.org/10.1158/1541-7786.c.6545157.v1
Autor:
C. Marcelo Aldaz, Aysegul Sahin, Steve Horvath, Tao Shi, Sally Gaddis, Maria I. Nunez, Yuhui Hu, Jeffrey A. Drake, Kathleen A. Hawkins, Hongxia Sun, Martín C. Abba
Supplementary Table S1 from Breast Cancer Molecular Signatures as Determined by SAGE: Correlation with Lymph Node Status
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0892f94135b47c8fa62073a44bbc823e
https://doi.org/10.1158/1541-7786.22520764
https://doi.org/10.1158/1541-7786.22520764
Autor:
C. Marcelo Aldaz, Daniel Medina, Powel H. Brown, Reid P. Bissonnette, Jamal Hill, Frances S. Kittrell, Sally Gaddis, Carla C. Levy, Yuhui Hu, Martín C. Abba
Supplementary Materials 1 from Identification of Modulated Genes by Three Classes of Chemopreventive Agents at Preneoplastic Stages in a p53-Null Mouse Mammary Tumor Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818447d531581a36020ae103905a747e
https://doi.org/10.1158/1940-6207.22523746
https://doi.org/10.1158/1940-6207.22523746
Autor:
Kornelia Polyak, Joe Gray, Catherine Wu, Joon Jeong, So Yeon Park, C. Marcelo Aldaz, Bojana Jovanović, Jennifer Eng, Guillaume Thibault, Young Hwan Chang, Koei Chin, Sachet A. Shukla, Carlos R. Gil Del Alcazar, Anne Trinh
Summary of Supplementary Tables Supplementary Table S1. Clinicopathological characteristics of patient cohort Supplementary Table S2. Antibody panel for cyclic IF Supplementary Table S3. Summary of mutations and neoantigen expression in the recurrenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8219f4c5adf6583a5ab90bb7c999c7a1
https://doi.org/10.1158/1541-7786.22526625.v1
https://doi.org/10.1158/1541-7786.22526625.v1