Zobrazeno 1 - 10
of 227
pro vyhledávání: '"C. Manivel"'
Caloric restriction (CR) and endurance exercise elicit wide-ranging health benefits including reduced risk of select cancers. In addition, diet composition influences oncogenesis, although its interactions with exercise and CR are not well understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::937131cc23faff12e176ff33336f2af8
https://doi.org/10.1158/1940-6207.c.6547655.v1
https://doi.org/10.1158/1940-6207.c.6547655.v1
Supplemental Data from Caloric Restriction Prevents Carcinogen-Initiated Liver Tumorigenesis in Mice
Fig. S1. Phenotypic and metabolic parameters are influenced by Ex and CR. Fig. S2. CR modulates additional markers of hepatic inflammation and immune cell infiltration. Fig. S3. CR causes divergence of genes in comparison to CTL mice. Fig. S4. CR aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7387518cf049ec516759c6d090b5d8f9
https://doi.org/10.1158/1940-6207.22534793
https://doi.org/10.1158/1940-6207.22534793
Akademický článek
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Publikováno v:
Case Reports in Clinical Medicine. 10:403-411
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::349b6168abdb99a619d9be1838c7087c
https://doi.org/10.4236/crcm.2021.1012050
https://doi.org/10.4236/crcm.2021.1012050
Autor:
Hector Mesa, J C Manivel, Umar Hayat, Carlos Iwamoto, Susan Dachel, Hira Yousaf, Brian J. Hanson, Amy Gravely, Wendy Larson, Justin Peltola
Publikováno v:
American Journal of Clinical Pathology. 153:695-704
Objectives Many studies have shown poor reproducibility among pathologists for diagnosing dysplasia in Barrett’s esophagus (BE). Immunohistochemical stains (IHC) are not widely used due to overlapping expression patterns in reactive and dysplastic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbcf27414fdb26a0d975dccd6e87050f
https://doi.org/10.1093/ajcp/aqaa004
https://doi.org/10.1093/ajcp/aqaa004
Publikováno v:
International Journal of Surgical Pathology. 28:20-30
Aims. The proximal colon derives from the midgut endoderm, the distal one third derives from the hindgut endoderm, and the distal anal canal is of ectodermal origin. At least 5 molecular subtypes of colorectal carcinomas (CRC) have been identified, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b939d8debfcf14afbcb8083b2e39ee
https://doi.org/10.1177/1066896919859096
https://doi.org/10.1177/1066896919859096
Autor:
Jessica L. Lapiro, J C Manivel, Heng Wu, Laurie L. Shekels, Douglas G. Mashek, Jeffrey H. Albrecht, Jonathan M. Ploeger, Sushama Kamarajugadda, Mara T. Mashek
Publikováno v:
Hepatology Communications
During normal proliferation, hepatocytes accumulate triglycerides (TGs) in lipid droplets (LDs), but the underlying mechanisms and functional significance of this steatosis are unknown. In the current study, we examined the coordinated regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777d7ce8151502ed0c18fdde9efe053b
https://doi.org/10.1002/hep4.1316
https://doi.org/10.1002/hep4.1316
Autor:
Brian J. Hanson, J C Manivel, Hector Mesa, Susan Dachel, Aastha Chauhan, Amy Gravely, Monica Sanchez-Avila, Wendy Larson
Publikováno v:
Applied immunohistochemistrymolecular morphology : AIMM. 29(1)
Adenocarcinomas of the esophagus (EAC), stomach [gastric adenocarcinoma (GAC)], and colorectal carcinoma (CRC) frequently show similar morphology because upper gastrointestinal tumors (GITs) usually evolve from pathologies involving intestinal metapl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9cb482ee4a4f690e6e359091f83a5d
https://pubmed.ncbi.nlm.nih.gov/33295746
https://pubmed.ncbi.nlm.nih.gov/33295746
Autor:
Teresa Cassel, Udayan Apte, Jessica L. Lapiro, Klaus H. Kaestner, Piotr Sicinski, Ashleigh Morgan, Shilpa Rao, Tzachi Reizel, J C Manivel, Matthew S. Rassette, Jeffrey H. Albrecht, Heng Wu, Jonathan Schug, Andrew N. Lane, Laurie L. Shekels, Yue J. Wang, Betsy T. Kren, Sumedha Gunewardena, Adam Herman, Teresa W.-M. Fan
Publikováno v:
Proc Natl Acad Sci U S A
Hepatocyte nuclear factor 4α (HNF4α) is a master regulator of liver function and a tumor suppressor in hepatocellular carcinoma (HCC). In this study, we explore the reciprocal negative regulation of HNF4α and cyclin D1, a key cell cycle protein in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::113daf4bdc10370796d720173f1b8701
https://europepmc.org/articles/PMC7382236/
https://europepmc.org/articles/PMC7382236/
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 70(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86ddadd74dd15176ad8f667812b518c
https://pubmed.ncbi.nlm.nih.gov/32520329
https://pubmed.ncbi.nlm.nih.gov/32520329