Zobrazeno 1 - 10
of 316
pro vyhledávání: '"C. Mande"'
Publikováno v:
Current Research in Structural Biology, Vol 8, Iss , Pp 100157- (2024)
Class I ribonucleotide reductases consisting of α and β subunits convert ribonucleoside diphosphates to deoxyribonucleoside diphosphates involving an intricate free radical mechanism. The generation of free radicals in the Class Ib ribonucleotide r
Externí odkaz:
https://doaj.org/article/70e18a12021e4d0a8c2a0d92b27831a3
Autor:
Nitin Bayal, Sunil Nagpal, Mohammed Monzoorul Haque, Milind S. Patole, Yogesh Shouche, Shekhar C. Mande, Sharmila S. Mande
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Although skin is the primary affected organ in Leprosy, the role of the skin microbiome in its pathogenesis is not well understood. Recent reports have shown that skin of leprosy patients (LP) harbours perturbed microbiota which grants infla
Externí odkaz:
https://doaj.org/article/0210b6b4b58d4191b4181edecd189966
Autor:
C. M. Santosh Kumar, Kritika Chugh, Anirban Dutta, Vishnuvardhan Mahamkali, Tungadri Bose, Sharmila S. Mande, Shekhar C. Mande, Peter A. Lund
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The ability of chaperonins to buffer mutations that affect protein folding pathways suggests that their abundance should be evolutionarily advantageous. Here, we investigate the effect of chaperonin overproduction on cellular fitness in Escherichia c
Externí odkaz:
https://doaj.org/article/eb5b30b54c09404c8adb0bb89a87ac80
Autor:
Gaurang Mahajan, Shekhar C. Mande
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background A comprehensive map of the human-M. tuberculosis (MTB) protein interactome would help fill the gaps in our understanding of the disease, and computational prediction can aid and complement experimental studies towards this end. Se
Externí odkaz:
https://doaj.org/article/da04dd60fbf246288c382d762e44c4d4
Autor:
Gunjan Arora, Andaleeb Sajid, Richa Virmani, Anshika Singhal, C. M. Santosh Kumar, Neha Dhasmana, Tanya Khanna, Abhijit Maji, Richa Misra, Virginie Molle, Dörte Becher, Ulf Gerth, Shekhar C. Mande, Yogendra Singh
Publikováno v:
npj Biofilms and Microbiomes, Vol 3, Iss 1, Pp 1-12 (2017)
Anthrax bacteria: a step in the pathway to biofilms An enzyme that adds phosphate groups to other proteins, PrkC, mediates molecular signaling events that allow anthrax bacteria to form biofilms. Bacillus anthracis is widely used as a model to explor
Externí odkaz:
https://doaj.org/article/4771965309c44fcba1e5d398d3205615
Autor:
S. Gaddam, C. Barroso, A. Pineda-Lucena, R. Conde, M.J. Simões, R. Laires, Manolis Matzapetakis, Ana Varela Coelho, L.G. Gonçalves, Shekhar C. Mande, M. Villar, Pedro Lamosa, S. Barnejee, Anant B. Patel, Arshad Rizvi, R. Macedo, Leonor Puchades-Carrasco
Publikováno v:
Biomedical Journal
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Background Tuberculosis (Tb) is a disease with worldwide presence and a major cause of death in several developing countries. Current diagnostic methodologies often lack specificity and sensitivity, whereas a long time is needed to obtain a conclusiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb19f2f69bb42b07183fa79ea481899
https://doi.org/10.1016/j.bj.2021.07.006
https://doi.org/10.1016/j.bj.2021.07.006
Autor:
Arshad Rizvi, Arvind Shankar, Ankita Chatterjee, Tushar H. More, Tungadri Bose, Anirban Dutta, Kannan Balakrishnan, Lavanya Madugulla, Srikanth Rapole, Sharmila S. Mande, Sharmistha Banerjee, Shekhar C. Mande
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Metabolic adaptation of Mycobacterium tuberculosis (M. tuberculosis) to microbicidal intracellular environment of host macrophages is fundamental to its pathogenicity. However, an in-depth understanding of metabolic adjustments through key reaction p
Externí odkaz:
https://doaj.org/article/02529eb3495744e8acfc211eef82c069
Publikováno v:
Biomolecules, Vol 10, Iss 6, p 938 (2020)
Decrypting the interface residues of the protein complexes provides insight into the functions of the proteins and, hence, the overall cellular machinery. Computational methods have been devised in the past to predict the interface residues using ami
Externí odkaz:
https://doaj.org/article/eb044996c11044f6916c543b40f69fec
Autor:
Mohammed Y. Ansari, Shekhar C. Mande
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
Chaperonins are a subclass of molecular chaperones that assist cellular proteins to fold and assemble into their native shape. Much work has been done on Type I chaperonins, which has elucidated their elegant mechanism. Some debate remains about the
Externí odkaz:
https://doaj.org/article/fc8b16863b3b40849bcc94c6b0187f31