Zobrazeno 1 - 10
of 78
pro vyhledávání: '"C. Malgouris"'
Autor:
Jean Marie Miquet, Marie-Claude Burgevin, M. Daniel, C. Malgouris, Mireille Meunier, Francoise Bordier, Colette Peny, Gabrielle Durand, Adam Doble, Jean-Charles Blanchard, Alain Boireau, Thierry Chevet, Serge Mignani, Patrick Jimonet
Publikováno v:
European Journal of Pharmacology. 300:237-246
The NMDA antagonist and neuroprotective effects of RPR 104632 (2H-1,2,4-benzothiadiazine-1-dioxide-3-carboxylic acid), a new benzothiadiazine derivative, with affinity for the glycine site of the NMDA receptor-channel complex are described. RPR 10463
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9da49b43d63294dec22001f209d4ea4
https://doi.org/10.1016/0014-2999(95)00780-6
https://doi.org/10.1016/0014-2999(95)00780-6
Autor:
Jean-Charles Blanchard, Adam Doble, M. Daniel, Thérèse Kiosseff, C. Malgouris, Fabienne Perrot, Marion Dupuis
Publikováno v:
Drug Development Research. 34:336-343
Suriclone is a potent non-benzodiazepine anxiolytic belonging to the cyclopyrrolone family. This study examines the distribution and properties of [3H]-suriclone binding sites in rat brain by autoradiography. The binding of [3H]-suriclone to rat brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7684414ff7187c9ba578cd32169c3fd
https://doi.org/10.1002/ddr.430340405
https://doi.org/10.1002/ddr.430340405
Autor:
Jeremy Pratt, A. Doble, Serge Mignani, Jean-Charles Blanchard, Jacques Lavayre, J.-M. Stutzmann, Michel Barreau, O. Piot, J. Rataud, P.M. Laduron, Patrick Jimonet, C. Malgouris, Alain Boireau, Michel Reibaud
Publikováno v:
Bioorganic & Medicinal Chemistry. 2:793-798
RP 66055, a riluzole derivative, has been characterized as a potent anticonvulsant and in vivo neuroprotective agent.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3595ed1fd47fa75540fe6bd274aadbe4
https://doi.org/10.1016/s0968-0896(00)82179-3
https://doi.org/10.1016/s0968-0896(00)82179-3
Publikováno v:
Neuroscience Letters. 177:95-99
The neuroprotective activity of riluzole has been studied on N- methyl- d -aspartate (NMDA)- or veratridine-induced toxicity in immature rat hippocampal slices. Neurodegeneration was assessed by the measurement of LDH release and histology. Veratridi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5d9ef0191e64bc34e571319728b81c6
https://doi.org/10.1016/0304-3940(94)90053-1
https://doi.org/10.1016/0304-3940(94)90053-1
Publikováno v:
European Journal of Pharmacology. 233:29-35
In this study, quantitative autoradiography was used to determine the selectivity of RP 62203, a novel naphtosultam derivative, for 5-HT2 receptors in vitro and ex vivo, using [125I]7-amino-8-iodo-ketanserin ([125I]AMIK) and [3H]mesulergine as radiol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c641ecd26d3c1bc63c00224f2546ea46
https://doi.org/10.1016/0014-2999(93)90345-i
https://doi.org/10.1016/0014-2999(93)90345-i
Autor:
A. Doble, Thierry Canton, J.-M. Stutzmann, C Pauchet, O. Piot, M C Bardone, C. Malgouris, Jean-Charles Blanchard
Publikováno v:
European psychiatry : the journal of the Association of European Psychiatrists. 10
SummaryThe mechanism of action of the cyclopyrrolone hypnotic drug zopiclone involves allosteric modulation of the GABAAreceptor. Zopiclone displaces the binding of [3H]-flunitrazepam with an affinity of 28 nM, and enhances the binding of the channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6d3d1c6d3619dcde945a99527e0301
https://pubmed.ncbi.nlm.nih.gov/19698408
https://pubmed.ncbi.nlm.nih.gov/19698408
Publikováno v:
Neuroscience. 36:425-430
Although the existence of receptor transport has been clearly demonstrated in peripheral nerves, there is no clear cut evidence in the brain of such a process for neuropeptide receptors. Because of the localization of neurotensin receptors on dopamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fadbefa9794f887db8cf4aabf14157
https://doi.org/10.1016/0306-4522(90)90438-a
https://doi.org/10.1016/0306-4522(90)90438-a
Publikováno v:
Annals of the New York Academy of Sciences. 668:320-322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4cd8621351b56ee11a643bd999e918e
https://doi.org/10.1111/j.1749-6632.1992.tb27363.x
https://doi.org/10.1111/j.1749-6632.1992.tb27363.x
Publikováno v:
Neuroscience letters. 177(1-2)
The neuroprotective activity of riluzole has been studied on N-methyl-D-aspartate (NMDA)- or veratridine-induced toxicity in immature rat hippocampal slices. Neurodegeneration was assessed by the measurement of LDH release and histology. Veratridine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17f5f5937466b8820db3c9a25df24355
https://pubmed.ncbi.nlm.nih.gov/7824190
https://pubmed.ncbi.nlm.nih.gov/7824190