Zobrazeno 1 - 7
of 7
pro vyhledávání: '"C. M. Yea"'
Publikováno v:
Biochemical pharmacology. 61(2)
HR325 (2-cyano-3-cyclopropyl-3-hydroxy-N-[3'-methyl-4'(trifluoromethyl)-phenyl]-propenamide) is an immunomodulatory compound through pyrimidine biosynthesis inhibition with antiproliferative properties which was derived from the isoxazol compound A77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a2062666249248a5a516772e012297b5
https://pubmed.ncbi.nlm.nih.gov/11163337
https://pubmed.ncbi.nlm.nih.gov/11163337
Autor:
A P, Curnock, P A, Robson, C M, Yea, D, Moss, S, Gadher, T A, Thomson, R, Westwood, E, Ruuth, R A, Williamson
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 282(1)
The relative anti-inflammatory activities of the immunomodulators HR325 and leflunomide, or its active metabolite A77 1726, were examined by determining potencies in vitro on prostaglandin endoperoxide H synthase (PGHS) and in vivo in rat air pouch i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22626f2d8a609b0a3cc88d13782a965e
https://pubmed.ncbi.nlm.nih.gov/9223572
https://pubmed.ncbi.nlm.nih.gov/9223572
Autor:
R A, Williamson, C M, Yea, P A, Robson, A P, Curnock, S, Gadher, A B, Hambleton, K, Woodward, J M, Bruneau, P, Hambleton, S, Spinella-Jaegle, P, Morand, O, Courtin, C, Sautés, R, Westwood, T, Hercend, E A, Kuo, E, Ruuth
Publikováno v:
Transplantation proceedings. 28(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::750bde00bce34adf3759b41e9842c707
https://pubmed.ncbi.nlm.nih.gov/8962196
https://pubmed.ncbi.nlm.nih.gov/8962196
Publikováno v:
Annals of the rheumatic diseases. 50(6)
An inhibitor of myeloperoxidase has been identified in the synovial fluids and sera from patients with rheumatoid arthritis and sera from normal subjects. Initially, these fluids were found to inhibit stimulus induced degranulation of polymorphonucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fabd69e35749159152668b6042854edd
https://pubmed.ncbi.nlm.nih.gov/1647755
https://pubmed.ncbi.nlm.nih.gov/1647755
Publikováno v:
Clinical and experimental immunology. 84(2)
SUMMARY An inhibitor of myeloperoxidase (MPO) has been identified in normal human serum. Initial experiments confirmed that high levels of MPO inhibitory activity are present in sera and that the inhibitor did not act by interfering with the assay. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::856bd62b850679ecf93c466ef027cf45
https://pubmed.ncbi.nlm.nih.gov/1851058
https://pubmed.ncbi.nlm.nih.gov/1851058
The 45 kDa diphenylene iodonium-binding flavoprotein of the human neutrophil superoxide-generating oxidase has been purified by affinity chromatography. The polypeptide was eluted from Blue Memsep or 2′,5′-ADP-agarose columns with either NADP or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1f6ccbc0a381ca7969383bf529fe84
https://europepmc.org/articles/PMC1136618/
https://europepmc.org/articles/PMC1136618/
Autor:
J. I. Ruzek, C. M. Yeager
Publikováno v:
Cambridge Prisms: Global Mental Health, Vol 4 (2017)
Internet and mobile technologies offer potentially critical ways of delivering mental health support in low-resource settings. Much evidence indicates an enormous negative impact of mental health problems in low- and middle-income countries (LMICs),
Externí odkaz:
https://doaj.org/article/876614216f4f4aca81ede5cd8ed0f110