Zobrazeno 1 - 4
of 4
pro vyhledávání: '"C. M. Walls"'
Autor:
D. A. Rose, A. Barrow, P. N. Spalton, R. D. Brownsill, Y. Gunn, C. M. Walls, N. J. Haskins, R. F. Palmer
Publikováno v:
Xenobiotica. 10:219-228
1. The disposition of [14C]pranolium chloride, a dimethyl quaternary derivative of propranolol, has been studied in rats, mice and hamsters after oral or parenteral dosage.2. Elimination of 14C occurred largely via the kidneys after parenteral dosage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::114b595043a2cb6f90b32a1883fc8cfa
https://doi.org/10.3109/00498258009033748
https://doi.org/10.3109/00498258009033748
Publikováno v:
Xenobiotica. 18:1413-1423
1. 14C-Bemitradine (50 mg) was rapidly and efficiently absorbed (approximately 89%) in man following a single oral dose, as a solution in gelatine capsules. Peak 14C levels of 895 +/- 154 ng equiv./ml (mean +/- S.E.M.) were reached within 2 h, and de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adfa9b88f9ee4d9ec76bf3282f4e4d7b
https://doi.org/10.3109/00498258809042264
https://doi.org/10.3109/00498258809042264
Publikováno v:
Bioanalysis of Drugs and Metabolites, Especially Anti-Inflammatory and Cardiovascular ISBN: 9781475794267
Hydroxylation is probably the most common Phase I metabolic pathway for xenobiotics. It is also a pathway readily detectable by MS from the 16 a.m.u. mass shift for the metabolite ions relative to those of the parent compound. However, such informati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf334bf3c784dfffbb847815d8e4429
https://doi.org/10.1007/978-1-4757-9424-3_51
https://doi.org/10.1007/978-1-4757-9424-3_51
Autor:
P. M. Stevens, D. A. Rose, T. J. Forrest, S. R. Burford, A. Barrow, C. W. Vose, A. J. Hawkins, C. M. Walls
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 12(2)
The disposition and metabolism of a 5-nitroimidazole compound (SC 28538) was investigated in the rat, beagle dog and rhesus monkey. The absorption of [14C]-SC 28538 was rapid and essentially complete after oral dosage in male animals, and also after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f514cccf77231204fe21cacce93e15f9
https://pubmed.ncbi.nlm.nih.gov/3121339
https://pubmed.ncbi.nlm.nih.gov/3121339