Zobrazeno 1 - 8
of 8
pro vyhledávání: '"C. M. Wait"'
Autor:
Martin T. Egeland, Marta M. Tarczyluk-Wells, Melissa M. Asmar, Evan G. Adintori, Roger Lawrence, Elizabeth M. Snella, Jackie K. Jens, Brett E. Crawford, Jill C. M. Wait, Emma McCullagh, Jason Pinkstaff, Jonathan D. Cooper, N. Matthew Ellinwood
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Abstract Mucopolysaccharidosis type IIIB (MPS IIIB; Sanfilippo syndrome B) is an autosomal recessive lysosomal storage disorder caused by the deficiency of alpha-N-acetylglucosaminidase activity, leading to increased levels of nondegraded heparan sul
Externí odkaz:
https://doaj.org/article/5500192f556445fb9991fe7f6927c244
Publikováno v:
Drug Metabolism and Disposition. 40:1515-1526
Carboxylic acid-containing nonsteroidal anti-inflammatory drugs (NSAIDs) can be metabolized to chemically reactive acyl glucuronide and/or S-acyl-CoA thioester metabolites capable of transacylating GSH. We investigated the metabolism of the NSAID mef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde80e7dbf2a7269556d1b58e97c1f36
https://doi.org/10.1124/dmd.112.046102
https://doi.org/10.1124/dmd.112.046102
Flunoxaprofen (FLX) is a chiral nonsteroidal anti-inflammatory drug that was withdrawn from clinical use because of concerns of potential hepatotoxicity. FLX undergoes highly stereoselective chiral inversion mediated through the FLX-S-acyl-CoA thioes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d09133fc0f400011101115555f4644cd
https://europepmc.org/articles/PMC2802421/
https://europepmc.org/articles/PMC2802421/
Autor:
Mohammed Jemal, Samuel J. Bonacorsi, James Mitroka, J. Kent Rinehart, Sanaullah Khan, Jill C. M. Wait, Nimish Vaccharajani, Ramaswamy A. Iyer
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 34(6)
This study describes the pharmacokinetic parameters of gemopatrilat, a potent vasopeptidase inhibitor, in humans and the comparative biotransformation of the compound in rats, dogs, and humans after administration of a single oral dose of [14C]gemopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53a2fbc580b0114f46a3ec938a576cb
https://pubmed.ncbi.nlm.nih.gov/16540589
https://pubmed.ncbi.nlm.nih.gov/16540589
Autor:
P. S. Laurie, C. A. Wareham, B. A. Thornley, C. R. Eatock, D. G. Willatts, R. S. Sanders, C. M. Wait
Editor—All doctors in Britain are concerned about the effects of chronic underfunding of health care, but a recent letter from two of our former senior house officers, Dr Jolante Sliwowska and Dr Przemek Jakubowski, highlights how bad things are in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e9709a0d47f037a758ebe4dcb1c394
https://europepmc.org/articles/PMC2127799/
https://europepmc.org/articles/PMC2127799/
Autor:
C. M. Wait, V. A. Goat
Publikováno v:
Survey of Anesthesiology. 34:95
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66d84f4fa6df30f1b248d1609d788d1d
https://doi.org/10.1097/00132586-199004000-00037
https://doi.org/10.1097/00132586-199004000-00037
Publikováno v:
Anaesthesia. 42:1212-1217
Summary A simple system for closed-loop control of neuromuscular blockade is described. It comprises a Datex Relaxograph, a small relay and a syringe pump. The equipment is commercially available and requires no complex custom-built electronics. Atra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e7d6375d441954521ecbdc345b78c0
https://doi.org/10.1111/j.1365-2044.1987.tb05233.x
https://doi.org/10.1111/j.1365-2044.1987.tb05233.x
Autor:
C. M. Wait, V. A. Goat
Publikováno v:
Anaesthesia. 44(7)
Summary A simple feedback control system was used to administer atracurium to 10 infants aged between 5 and 36 months during craniofacial reconstruction. The purpose of the study was to establish whether the system, previously evaluated only in adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aed140d9fe864fb6b2ce76515f7e1fa
https://pubmed.ncbi.nlm.nih.gov/2549801
https://pubmed.ncbi.nlm.nih.gov/2549801