Zobrazeno 1 - 10
of 18
pro vyhledávání: '"C. M. Lindgren"'
Publikováno v:
Equine Veterinary Education. 33:475-483
Autor:
Christoffer Nellåker, Stefan Ruschke, Melina Claussnitzer, Dimitrios C. Karampinos, C M Lindgren, Sophie Strobel, Samantha Laber, Hans Hauner, Ulrich Kulozik, Julius Honecker, P. Proell, J. Ecker, C. Seeliger
Adipose tissue is an organ with great plasticity and its hypertrophic expansion is associated with adipocyte dysfunction. How changes in adipocyte morphology are linked to gene expression and which cellular functions are affected remains elusive. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6184cb557225f0598e34e0ac563a7ad2
https://doi.org/10.1101/2021.11.20.468818
https://doi.org/10.1101/2021.11.20.468818
Variation in sequence mutability has important implications for evolutionary models and predicting disease occurrence, and is driven in part by evolutionary divergence in mechanisms of DNA repair. The aim of this study was twofold: first, to assess t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0d1a9a9c73ec8af5da4129cf60bc0b8
https://doi.org/10.1101/2021.06.22.449367
https://doi.org/10.1101/2021.06.22.449367
Autor:
Stefan Gross, Honghuang Lin, Diane T. Smelser, März W, Niek Verweij, Alexander Niessner, Peter M. Visscher, Ruth C. Lovering, Erik Ingelsson, Nicholas L. Smith, Lars Lind, Jerome I. Rotter, Anna Helgadottir, David J. Stott, Michelle L. O'Donoghue, Daniel I. Chasman, Karoline Kuchenbaecker, Morris Ad, Michael W. Nagle, Morris Ap, Steven A. Lubitz, Giedraitis, Abirami Veluchamy, Paul M. Ridker, David J. Carey, Benoit Tyl, Carolina Roselli, Laura M. Yerges-Armstrong, Michael R. Brown, Faiez Zannad, Aroon D. Hingorani, Åsa K. Hedman, Nilesh J. Samani, Daníel F. Guðbjartsson, Maris Teder-Laving, Stephan B. Felix, Christopher Newton-Cheh, Marcus Dörr, Thomas P. Cappola, Daniel I. Swerdlow, Leonard Buckbinder, Xiaosong Wang, Alex S. F. Doney, C. Andersson, Jonathan H. Chung, Joshua D. Backman, Tõnu Esko, Mohsen Ghanbari, Joop Jukema, Ian Ford, Gunnar Engström, Kent D. Taylor, Johan Ärnlöv, P.E Weeke, Kenneth B. Margulies, Peter Svensson, Folkert W. Asselbergs, Lars Køber, Michael V. Holmes, Anders Mälarstig, Chim C. Lang, Krishna G. Aragam, Samuel C. Dudley, Christian Torp-Pedersen, Bruce M. Psaty, Alexander Teumer, John J.V. McMurray, Raul Weiss, Smith Jg, Patrick T. Ellinor, Anjali T. Owens, Ify R. Mordi, G Sveinbjörnsson, Luca A. Lotta, John S. Gottdiener, Christopher M. Haggerty, Christopher P. Nelson, C M Lindgren, Hilma Holm, Michael E. Dunn, Albert Henry, Helen M. Parry, Salomaa, Huilin Xing, Kenneth Rice, Marcus E. Kleber, Spiros Denaxas, Chris Finan, Xu Chen, Unnur Thorsteinsdottir, Naveed Sattar, Bing Yu, Kerri L. Wiggins, Alaa Shalaby, Romaine Spr., Patrik K. E. Magnusson, Adriaan A. Voors, Lumbers Rt, Stella Trompet, Maryam Kavousi, Kari Stefansson, Jian'an Luan, Harry Hemingway, van Setten J, Anubha Mahajan, Olle Melander, Uwe Völker, Peter Almgren, Chaffin, Palmer Cna., Eliana Portilla-Fernandez, Stefan Stender, Markus Perola, Guðmundur Thorgeirsson, Ghazaleh Fatemifar, Teemu J. Niiranen, Nicholas J. Wareham, Andrea Koekemoer, James P. Cook, Jeff Brandimarto, Jian Yang, Mary L. Biggs, Claudia Langenberg, Perttu Salo, Sonia Shah, A.G. Uitterlinden, Mari-Liis Tammesoo, Jemma B. Wilk, Craig L. Hyde, Graciela E. Delgado, van der Harst P, Alanna C. Morrison, Kay-Tee Khaw, Barry London, Rebecca Gutmann, Thomas M. Morgan, Franco Giulianini, Abbas Dehghan, Heather L. Bloom, William A. Chutkow, Dawn M. Waterworth, Ramachandran S. Vasan, Jing Hua Zhao, Morley Mp, Sahar Ghasemi
Heart failure (HF) is a leading cause of morbidity and mortality worldwide1. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933d4afcda47cac337d25ebb3c94668b
Autor:
Julius Honecker, Sara L. Pulit, E. Pastel, Melina Claussnitzer, Hans Hauner, Christian M. Becker, Jenny C Censin, Nicola L. Beer, Andrew Pitt, Christoffer Nellåker, Samantha Laber, Michelle Hudson, Krina T. Zondervan, C M Lindgren, K. Kos, Timothy M. Frayling, Craig A. Glastonbury, Hanieh Yaghootkar, Nilufer Rahmioglu
Genetic studies have recently highlighted the importance of fat distribution, as well as overall adiposity, in the pathogenesis of obesity-associated diseases. Using a large study (n = 1,288) from 4 independent cohorts, we aimed to investigate the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053ad6263b67d4a5de7cf75e3c42e32c
https://doi.org/10.1101/680637
https://doi.org/10.1101/680637
Autor:
Dennis O. Mook-Kanamori, J M Gaziano, Harst Pvd., Derek Klarin, K A Birdwell, Josh C. Denny, Martin Farrall, Thibaud Boutin, Najim Lahrouchi, Nabi Shah, Scott M. Damrauer, Cecilia P. Chung, Neil Poulter, Herzig K-H., E E Siew, John Concato, Yan V. Sun, Sara M. Willems, Louise V. Wain, Philip S. Tsao, Massimo Mangino, Wei W-Q., Ioanna Ntalla, Brian S. Mautz, David Schlessinger, Daniel I. Chasman, Branwen J. Hennig, Christopher Newton-Cheh, Michael E. Matheny, Palmer Cna., Caroline Hayward, Zhao J-H., Eleftheria Zeggini, Paul Elliott, C M Lindgren, Praveen Surendran, Csaba P. Kovesdy, Jacob M. Keaton, Chengxiang Qiu, Claudia Langenberg, Christopher Oldmeadow, Stéphanie Debette, D.R. Velez Edwards, Evangelos Evangelou, Howson Jmm., Adriana M. Hung, Yaomin Xu, Nicholas J. Wareham, James P. Cook, Scott L. DuVall, Peter Almgren, Jacklyn N. Hellwege, Sébastien Thériault, Helen R. Warren, Jian'an Luan, Ching-Ti Liu, Christopher J. O'Donnell, Michael Boehnke, Peter S. Sever, Ruifang Li-Gao, Cassianne Robinson-Cohen, Robert A. Scott, Muralidharan Sargurupremraj, Mark J. Caulfield, Jarvelin M-R., Tim D. Spector, Todd L. Edwards, Elena V. Feofanova, Francesco Cucca, Jihwan Park, Savita Karthikeyan, J C Smith, Wilson Pwf., Markku Laakso, Ayush Giri, Christianne L. Roumie, Rojesh Shrestha, Claudia P. Cabrera, Kelly Cho, Laura J. Scott, Elvis A. Akwo, Yu Wang, Tom G. Richardson, Patricia B. Munroe, Eric S. Torstenson, Katalin Susztak, John Attia, Bruce M. Psaty, Aldi T. Kraja, Olle Melander, Nicholas J. Timpson, George Dedoussis, Paul M. Ridker, Niek Verweij, David Conen, Philippe Amouyel, Otis D. Wilson, Nuno Sepúlveda
Publikováno v:
NATURE GENETICS
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.51-62. ⟨10.1038/s41588-018-0303-9⟩
Nature Genetics, 51(1), 51
Nature genetics, 51(1), 51-62. Nature Publishing Group
Nature Genetics, 51(1), 51-62. Nature Publishing Group
Giri, A, Hellwege, J N, Keaton, J M, Park, J, Qiu, C, Warren, H R, Torstenson, E S, Kovesdy, C P, Sun, Y V, Wilson, O D, Robinson-Cohen, C, Roumie, C L, Chung, C P, Birdwell, K A, Damrauer, S M, DuVall, S L, Klarin, D, Cho, K, Wang, Y, Evangelou, E, Cabrera, C P, Wain, L V, Shrestha, R, Mautz, B S, Akwo, E A, Sargurupremraj, M, Debette, S, Boehnke, M, Scott, L J, Luan, J, Zhao, J-H, Willems, S M, Thériault, S, Shah, N, Oldmeadow, C, Almgren, P, Li-Gao, R, Verweij, N, Boutin, T S, Mangino, M, Ntalla, I, Feofanova, E, Surendran, P, Cook, J P, Richardson, T G, Zeggini, E, Scott, R A, Palmer, C N A & Timpson, N J & Wilson, P W F 2019, ' Trans-ethnic association study of blood pressure determinants in over 750,000 individuals ', Nature Genetics, vol. 51, no. 1, pp. 51-62 . https://doi.org/10.1038/s41588-018-0303-9
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.51-62. ⟨10.1038/s41588-018-0303-9⟩
Nature Genetics, 51(1), 51
Nature genetics, 51(1), 51-62. Nature Publishing Group
Nature Genetics, 51(1), 51-62. Nature Publishing Group
Giri, A, Hellwege, J N, Keaton, J M, Park, J, Qiu, C, Warren, H R, Torstenson, E S, Kovesdy, C P, Sun, Y V, Wilson, O D, Robinson-Cohen, C, Roumie, C L, Chung, C P, Birdwell, K A, Damrauer, S M, DuVall, S L, Klarin, D, Cho, K, Wang, Y, Evangelou, E, Cabrera, C P, Wain, L V, Shrestha, R, Mautz, B S, Akwo, E A, Sargurupremraj, M, Debette, S, Boehnke, M, Scott, L J, Luan, J, Zhao, J-H, Willems, S M, Thériault, S, Shah, N, Oldmeadow, C, Almgren, P, Li-Gao, R, Verweij, N, Boutin, T S, Mangino, M, Ntalla, I, Feofanova, E, Surendran, P, Cook, J P, Richardson, T G, Zeggini, E, Scott, R A, Palmer, C N A & Timpson, N J & Wilson, P W F 2019, ' Trans-ethnic association study of blood pressure determinants in over 750,000 individuals ', Nature Genetics, vol. 51, no. 1, pp. 51-62 . https://doi.org/10.1038/s41588-018-0303-9
International audience; In this trans-ethnic multi-omic study, we reinterpret the genetic architecture of blood pressure to identify genes, tissues, phenomes and medication contexts of blood pressure homeostasis. We discovered 208 novel common blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc65101b526e49b26bca973f7ee89ec
Autor:
Nilufer Rahmioglu, Duncan S. Palmer, Christian M. Becker, Samantha Laber, Andres Salumets, Viktorija Kukushkina, Margaret F. Lippincott, Jordan W. Smoller, Chiao-Lin Chen, Krina T. Zondervan, Neale Bm, Stephanie B. Seminara, Triin Laisk, C M Lindgren, Teresa Ferreira, Ingrid Granne, Reedik Mägi
The normal menstrual cycle requires a delicate interplay between the hypothalamus, pituitary, and ovary. Therefore, its length is an important indicator of female reproductive health. Menstrual cycle length has been shown to be partially controlled b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d412112cb380f49d75e438677df20a89
https://doi.org/10.1101/333708
https://doi.org/10.1101/333708
Autor:
E Staines Urias, Stephen Kennedy, Tshivuila-Matala Coo., Shama Munim, Shane A. Norris, Rose McGready, Zulfiqar A Bhutta, F Nosten, Katharina Wulff, Ann Lambert, M Carvalho, Eric O Ohuma, Rachel Craik, C M Lindgren, Manu Vatish, Christoffer Nellåker, F C Barros, G Zainab, James A. Berkley, Michelle Fernandes, William Stones, S Ash, Alan Stein, Cesar G. Victora, Hellen C. Barsosio, José Villar, Aris T. Papageorghiou, L Cheikh Ismail, Krina T. Zondervan, J.A. Noble, Ricardo Uauy
Publikováno v:
Gates Open Research
Background: INTERBIO-21st is Phase II of the INTERGROWTH-21st Project, the population-based, research initiative involving nearly 70,000 mothers and babies worldwide coordinated by Oxford University and performed by a multidisciplinary network of mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38394ba708170a5ba466bb7b26099eca
Autor:
Jonathan M. Locke, William D. Thompson, Jess Tyrrell, Rachel M. Freathy, West B, Beaumont Rn, James W. Harrison, Niels Grarup, C M Lindgren, Anna Murray, Francesco Casanova, Andrew R. Wood, Ruth Ks, Seth A. Sharp, Timothy M. Frayling, Yingjie Ji, Marcus A. Tuke, Samuel E. Jones, Michael N. Weedon, Hanieh Yaghootkar
SummaryFibroblast Growth Factor 21 (FGF21) is a hormone that induces weight loss in model organisms. These findings have led to trials in humans of FGF21 analogues with some showing weight loss and lipid lowering effects. Recent genetic studies have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2f852524791d5ec99f582e2f8df2e6
https://doi.org/10.1101/214700
https://doi.org/10.1101/214700
Autor:
Alexander W. Drong, E Makrinou, M Liyanage, T Caraderi, C M Lindgren, Stuart Lavery, Steve Franks, G Christopoulos, Avi Lerner, Kate Hardy
Publikováno v:
Endocrine Abstracts.