Zobrazeno 1 - 10
of 43
pro vyhledávání: '"C. M. Kuiper"'
Autor:
R. Niessen, J. Kroeze, K. Spreeuwenberg, J. J. Kok, R. M. A. Knegtel, S. V. Roosmalen-Vos, A. N. Vermeulen, D. Schaap, C. M. Kuiper, G. Arts, N. V. D. Beek-Verhoeven
Publikováno v:
Parasitology. 128:603-616
AnEimeria acervulinaprotein fraction was identified which conferred partial protection against anE. acervulinachallenge infection. From this fraction a 37 kDa protein was purified and its corresponding cDNA was cloned and shown to encode a lactate de
Autor:
Godefridus J. Peters, H. R. Hendriks, F. Myhren, C. M. Kuiper, M. L. Sandvold, A. M. Bergmann
Publikováno v:
Bergman, A M, Kuiper, C M, Myhren, F, Sandvold, ML, Hendriks, H R & Peters, G J 2004, ' Antiproliferative activity and mechanism of action of fatty acid derivatives of arabinosylcytosine (Ara-C) in leukemia and solid tumor cell lines ', Nucleosides, Nucleotides and Nucleic Acids, vol. 23, pp. 1523-1526 . https://doi.org/10.1081/NCN-200027735
Nucleosides, Nucleotides and Nucleic Acids, 23, 1523-1526. Taylor and Francis Ltd.
Nucleosides, Nucleotides and Nucleic Acids, 23, 1523-1526. Taylor and Francis Ltd.
Resistance to, the hydrophilic drug ara‐C, might be meditated by decreased membrane transport. Lipophillic prodrugs were synthesized to facilitate uptake. These compounds were equally active as ara‐C, while the compounds with the shortest fatty
Autor:
H.M. Pinedo, C. M. Kuiper, Godefridus J. Peters, Andries M. Bergman, C.J.A. van Moorsel, Jan B. Vermorken, G. Veerman, W.J.F. van der Vijgh
Publikováno v:
British Journal of Cancer
The British journal of cancer
The British journal of cancer
2′,2′-Difluorodeoxycytidine (gemcitabine, dFdC) and cis-diammine-dichloroplatinum (cisplatin, CDDP) are active agents against ovarian cancer and non-small-cell lung cancer (NSCLC). CDDP acts by formation of platinum (Pt)–DNA adducts; dFdC by dF
Autor:
Peter G. Scheffer, Wilbert H.M. Peters, Hennie M.M. Schlüper, C. A. M. Erkelens, A. H. Van Hattum, Epie Boven, C. M. Kuiper, G. Giaccone, H.M. Pinedo, J. van Ark-Otte
Publikováno v:
Scopus-Elsevier
British Journal of Cancer
British Journal of Cancer
We have established ten transplantable human soft-tissue sarcoma (STS) xenografts grown as subcutaneous tumours in the nude mouse. Nine xenografts originated from patients that needed chemotherapy in the course of their disease. The xenografts were t
Autor:
Jan P. A. Baak, C.K. van Kalken, Sabine C. Linn, P. van der Valk, H.M. Pinedo, W. M. D. Blokhuis, C. M. Kuiper, G. Giaccone, P. J. Van Diest
Publikováno v:
Scopus-Elsevier
Annals of Oncology, 6, 679-685. Oxford University Press
Linn, S C, Giaccone, G, van Diest, P J, Blokhuis, W M D, van der Valk, P, van Kalken, C K, Kuiper, C M, Pinedo, H M & Baak, J P A 1995, ' Prognostic relevance of P-glycoprotein expression in breast cancer ', Annals of Oncology, vol. 6, pp. 679-685 .
Annals of Oncology, 6, 679-685. Oxford University Press
Linn, S C, Giaccone, G, van Diest, P J, Blokhuis, W M D, van der Valk, P, van Kalken, C K, Kuiper, C M, Pinedo, H M & Baak, J P A 1995, ' Prognostic relevance of P-glycoprotein expression in breast cancer ', Annals of Oncology, vol. 6, pp. 679-685 .
Background : P-glycoprotein (Pgp) expression has been reported to be associated with a poor prognosis in some malignancies such as neuroblastoma, soft tissue sarcoma and acute myeloid leukemia. The prognostic role of Pgp expression in breast cancer i
Autor:
H.M. Pinedo, Jan Lankelma, N. Feller, J. K. Ruhdal, C. M. Kuiper, H. J. Broxterman, R.J. Scheper
Publikováno v:
British Journal of Cancer
British Journal of Cancer, 72, 543-549. Nature Publishing Group
Feller, N, Kuiper, C M, Lankelma, J, Ruhdal, J K, Scheper, R J, Pinedo, H M & Broxterman, H J 1995, ' Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry ', British Journal of Cancer, vol. 72, pp. 543-549 .
British Journal of Cancer, 72, 543-549. Nature Publishing Group
Feller, N, Kuiper, C M, Lankelma, J, Ruhdal, J K, Scheper, R J, Pinedo, H M & Broxterman, H J 1995, ' Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry ', British Journal of Cancer, vol. 72, pp. 543-549 .
Multidrug resistance (MDR) in tumour cells is often caused by the overexpression of the plasma membrane drug transporter P-glycoprotein (P-gp) or the recently discovered multidrug resistance-associated protein (MRP). In this study we investigated the
Autor:
G Veerman, C M Kuiper, Rudolph Willem, Godefridus J. Peters, Abdeslam Bouhdid, Marcel Gielen, Didier Devos
Publikováno v:
Oncology reports. 3(3)
The in vitro antiproliferative effects, the in vivo toxicity profiles in mice and the antitumour activity in tumour bearing mice were screened for four novel di-n-butyltin carboxylates, di-n-butyltin bis(2,4-dihydroxybenzoate) [compound 1 (C1)], di-n
Autor:
H. J. Broxterman, C.A. Eekman, C. M. Kuiper, H.M. Pinedo, Gerrit Jan Schuurhuis, C. H. M. Versantvoort, Jan Lankelma
Publikováno v:
Versantvoort, C H M, Schuurhuis, G J, Pinedo, H M, Eekman, C A, Kuiper, C M, Lankelma, J & Broxterman, H J 1993, ' Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells ', British Journal of Cancer, vol. 68, pp. 939-946 .
British Journal of Cancer, 68, 939-946. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer, 68, 939-946. Nature Publishing Group
British Journal of Cancer
In tumour cells the pharmacological basis for multidrug resistance (MDR) often appears to be a reduced cellular cytostatic drug accumulation caused by the drug efflux protein, P-glycoprotein (Pgp MDR), or by other drug transporters (non-Pgp MDR). Her
Autor:
Bridget T. Hill, L. K. Hosking, S. McClean, S. A. Shellard, W. C. M. Dempke, R. D. H. Whelan, M. Sehested, E. Friche, E. J. F. Demant, P. B. Jensen, B. P. Kopnin, B. Wolf, A. Seidel, M. Nickelsen, I. Brandt, G. Heinemann, M. Dietel, S. Bremer, T. Hoof, B. Tümmler, H. J. Broxterman, C. H. M. Versantvoort, C. M. Kuiper, N. Feller, G. J. Schuurhuis, J. Lankelma, S. Gupta, T. Tsuruo, C. Kim, S. Gollapudi, A. Bittl, M. Nap, W. Jäger, B. Lathan, N. Lang, N. T. Raikhlin, A. G. Perevozchikov, J. L. Volodina, T. Licht, H. H. Fiebig, K. J. Bross, F. Herrmann, R. Mertelsmann, I. Bashir, K. Sikora, C. S. Foster, M. Castagna, P. Viacava, M. Cianfrigliao, A. Favati, P. Collecchi, M. A. Caligo, G. Cipollini, G. Bevilacqua, D. Schrenk, T. W. Gant, J. A. Silverman, S. S. Thorgeirsson, A. Harstrick, Z. G. Zhang, H. J. Schmoll, Y. Rustum, M. Mitze, T. Beck, W. Weikel, C. Brumm, P. G. Knapstein, T. McDonald, P. Gardner, N. Kang, S. A. M. van der Heyden, H. J. Elst, U. Stein, B. Jandrig, H. Krause, P. Schmidt-Peter, J. Frege, V. Wunderlich, E. Boven, C. K. van Kalken, H. M. Pinedo, W. Gebauer, E. Fallgren-Gebauer, M. Diete, T. Wagner, M. R. Müller, K. Lennartz, H. R. Nowrousian, S. Seeber, A. A. Shtil, A. R. Kazarov, A. V. Gudkov, A. A. Stavrovskaya, F. H. Djuraeva, T. P. Stromskaya, A. Noller, G. Frese, M. Neumann, A. Wilisch, H. Probst, V. Gekeler, R. Handgretinger, H. Schmidt, C. P. Muller, R. Dopfer, T. Klingebiel, D. Niethammer, S. Weger, H. Diddens, E. Daumiller, A. Bunge, R. Lilischkis, A. Salmassi, M. Kopun, H. Scherthan, C. Granzow, I. Leuschner, D. Schmidt, H. Hoffmann, D. Harms, G. V. Scagliotli, E. Leonardo, S. Cappia, G. Esposito, M. Tombesi, M. Cianfriglia, G. V. Esposito, N. Merendino, M. Viora, M. Caserta, E. Tritarelli, E. Rocca, G. Boccoli, P. Samoggia, C. Fossati, U. Testa, C. Peschle, J. L. Darling, S. M. Ashmore, D. C. Peterson, D. G. T. Thomas, R. A. Kramer, R. Stanlunas, T. Summerhayes, T. Lion, R. H. Shoemaker, L. Wu, A. Smythe, M. R. Boyd, W. T. Beck, M. K. Danks, J. S. Wolverton, M. Chen, B. Y. Bugg, D. P. Suttle, C. V. Catapano, D. J. Fernandes, F. Gieseler, F. Boege, R. Erttmann, H. Arps, L. Zwelling, K. Wilms, H. Biersack, G. J. L. Kaspers, R. Pieters, E. Klumper, F. C. de Waal, E. R. van Wering, A. J. P. Veerman, C. A. Schmidt, F. Lorenz, A. Schäfer, A. Kirsch, W. Siegert, D. Huhn, W. E. Simon, G. Siebert, M. Schneider, M. Oettling, A. Reymann, R. Entmann, S. Schmidt, C. Woermann, C. Windmeier, I. Herzig, B. Schaefer, H. J. Heidebrecht, H. H. Wacker, H. Künnemann, Th. H. M. van Heijningen, M. L. Slovak, J. P. A. Baak, K. Steidtmann, A. -M. J. Fichtinger-Schepman, B. I. Hill, K. J. Scanlon, W. J. Zeller, G. Chen, J. A. Gietema, E. G. E de Vries, D.Th Sleijfer, P. H. B. Willemse, H. J. Guchelaar, D. R. A. Uges, P. Aulenbacher, R. Voegeli, N. H. Mulder, C. Skrezek, H. Bertermann, H. Eichholtz-Wirth, R. Born, H. Bier, M. Koch, G. Bernhardt, K. Hählen, H. Reile, C. H. van Zantwijk, T. Görögh, B. Lippert, J. A. Werner, J. E. Eickbohm, G. H. Mickiseh, M. M. Gottesman, I. Pastan, J. Hofmann, A. Wolf, M. Spitaler, G. Bock, H. Grunicke, H. Ponstingl, I. Roth, C. Dörner, G. Looft, G. J. Ossenkoppele, G. L. Scheffer, G. Atassi, A. Pierre, L. Kraus, S. Leonce, G. Regnier, A. Dhainaut, M. Stöhr, C. Rohlff, R. I. Glazer, Y. S. Cho-Chung, V. Höllt, M. Kouba, G. Vogt, H. Allmeier, N. I. Nissen, S. Cros, N. Guilbaud, T. Dunn, M. Berlion, J. P. Bizzari, A. M. Messing, A. Matuschek, I. Mutter, J. C. W. Kiwit, L. Bastian, P. E. Goretzki, A. Frilling, D. Simon, H. D. Röher, A. Reichle, F. Altmayr, J. Rastetter, C. Erbil, G. Jaques, M. Maasberg, K. Havemann, K. Häußermann, H. -J. Heidebrecht, W. Van de Vrie, E. E. O. Gheuens, N. M. C. Durante, E. A. De Bruijn, R. L. Marquet, A. T. Van Oosterom, A. M. M. Eggermont, M. W. Stow, S. E. Vickers, J. R. Warr, E. Roller, M. Eichelbaum, B. Klumpp, J. Krause, K. Schumacher, S. Hörner, A. Laßmann, U. Traugott, E. Schlick, D. Bürkle, BW Futscher, AF List, WS Dalton, E. Ladda, K. Bühl, A. Weimer, C. Eser, K. Hamprecht, K. P. Schalk, C. Jackisch, B. Brandt, M. Blum, F. Louwen, K. Schulz, J. P. Hanker, U. Rüther, A. Schmidt, H. A. G. Müller, C. Nunnensiek, H. Bader, F. Eisenberger, P. Jipp, B. Niethammer, C. Muller, V. Ling, F. Joncourt, S. Redmond, K. Buser, M. Fey, A. Tobler, K. Brunner, A. Gratwohl, T. Cerrry, V. Nuessler, R. Pelka-Fleischer, C. Nerl, B. Beckert, W. Wilmanns, S. Hegewisch-Becker, M. Fliegner, A. Zander, D. K. Hossfeld, J. Blanz, K. Mewes, G. Ehninger, K. -P. Zeller, H. Schuldes, G. Herrmann, W. Boeckmann, R. Schroeder, D. Jonas, K. -H. Zurborn, H. D. Bruhn, L. Uharek, B. Glass, W. Gassmann, H. Loeffler, W. Mueller-Ruohholtz, W. Mueller-Ruchholtz, K. Jaquet, H. Kreipe, J. Felgner, H. J. Radzun, M. R. Parwaresch, EA Kogan, NN Mazurenko, SM Sekamova, H. Wolf, K. Röhe, K. Wilkens, M. Clausen, E. Henze, J. van der Bosch, S. Rüller, M. Schlaak, U. Köhl, D. Schwabe, E. Rohrbach, E. Montag, S. Bauer, J. Cinatl, I. Cinatl, M. Mainke, H. Geiss, B. Kornhuber, H. Juhl, H. Stritzel, H. Kalhoff, W. Schniegel, T. Menke, B. Pröbsting, P. Schulze-Westhoff, J. Boos, J. Weidner, N. Wedemeyer, K. Wiedorn, Y. Ueda, S. Blasius, P. Wuisman, W. Böcker, A. Roessner, B. Dockhorn-Dworniczak, D. Ramm, J. Knebel, W. Sass, M. Aufderheide, J. Seifert
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 117:S89-S120
Autor:
H. Ketelaars, R.J. Scheper, Jan Lankelma, H.M. Pinedo, C.K. van Kalken, George L. Scheffer, C. J. L. M. Meijer, C. M. Kuiper, H. J. Broxterman, P. van der Valk, Takashi Tsuruo
Publikováno v:
Annals of Oncology. 1:56-64
Summary P-glycoprotein is a molecule strongly associated with multi-drug resistance to certain cytostatic drugs, including adriamycin, vincristine, and daunorubicin. Using 3 monoclonal antibodies directed at different epitopes of this molecule (JSB-1