Zobrazeno 1 - 10
of 25
pro vyhledávání: '"C. M. Heyworth"'
Autor:
Brotherton D, T. Meyers, S. Cribbes, James S. Owen, Anthony M. C. Brown, S. Palan, E. Randle, Neil R. Schofield, Sue E. Craig, R Christison, S J Evans, V. Appay, Jane A. McKeating, Peter J. Morgan, M G Hunter, J. R. Fisher, C M Heyworth, Lloyd George Czaplewski, N R Woods, L A Howard, P G Varley, R Gilbert, B I Lord, P. Tan, Garrick K. Wilson, Lee D. Higgins, R M Edwards, T. Dudgeon, Jonathan P. Waltho, C. J. Craven
Publikováno v:
Journal of Biological Chemistry. 274:16077-16084
Human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES (regulated on activation normal T cell expressed) self-associate to form high-molecular mass aggregates. To explore the biological significance of chemokine aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a7297ae87013b09066307ed155593d
https://doi.org/10.1074/jbc.274.23.16077
https://doi.org/10.1074/jbc.274.23.16077
Autor:
Brotherton D, T M Dexter, Michael George Hunter, Ajh Gearing, Lewis Pj, B I Lord, P G Varley, Stewart Craig, Richard Mark Edwards, S. Cribbes, A.H. Drummond, Lloyd George Czaplewski, Matthew John Mccourt, L. M. Wood, C M Heyworth, Lindsay Bawden
Publikováno v:
Blood. 86:4400-4408
The stem cell inhibitor, macrophage inflammatory protein-1 alpha (MIP-1 alpha) or LD78, protects multipotent hematopoietic progenitors in murine models from the cytotoxic effects of chemotherapy. Clinical use of human MIP-1 alpha during chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c0b0be715a017618d4ed69a5fdb99db
https://doi.org/10.1182/blood.v86.12.4400.bloodjournal86124400
https://doi.org/10.1182/blood.v86.12.4400.bloodjournal86124400
Autor:
C. M. Heyworth, T. M. Dexter
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 13:S3-S8
In the absence of appropriate growth factors, for example interleukin-3 or GM-CSF, cultured bone marrow stem cells die by a process known as apoptosis or programmed cell death. Apoptosis may occur in vivo when concentrations of specific growth factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afa2bdd12c432364c1473abfc4d677d
https://doi.org/10.1007/bf01973595
https://doi.org/10.1007/bf01973595
Autor:
Peter L. Stern, Maria H. Gilleece, Nydia G Testa, Anna K Ghosh, J. H. Scarffe, C M Heyworth, Eric M. Bonnem, TM Dexter
Publikováno v:
British Journal of Cancer
Recombinant Interleukin 4 was administered by subcutaneous injection at daily doses of 0.5, 1.0 or 5.0 micrograms kg-1 to nine patients as part of a Phase I Dose Toxicity Study. Dose limiting toxicity was reached at 5 micrograms kg-1 day-1. Symptoms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384b2e8f3473ad9142e12de81f943b45
https://doi.org/10.1038/bjc.1992.243
https://doi.org/10.1038/bjc.1992.243
Publikováno v:
Blood. 78:2588-2594
The effects of interferon-gamma (IFN-gamma) on a highly enriched population of granulocyte-macrophage colony-forming cells (GM-CFC) were assessed. When added with myeloid growth factors (interleukin-3 [IL-3], granulocyte-macrophage colony-stimulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def6cce167fa7ad2153a61144af0fdfb
https://doi.org/10.1182/blood.v78.10.2588.bloodjournal78102588
https://doi.org/10.1182/blood.v78.10.2588.bloodjournal78102588
Publikováno v:
Growth Factors. 4:165-173
A serum-free culture system was used to determine the effects of growth factors on the clonogenic development of a population of cells highly enriched for multipotential day 12 spleen colony forming cells (CFU-S) (FACS-BM). Under these conditions, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6fbdd547671d82559a40f449280311
https://doi.org/10.3109/08977199109104812
https://doi.org/10.3109/08977199109104812
Autor:
R Schiro, T. M. Dexter, J. Chang, L. H. Coutinho, T. D. Allen, C M Heyworth, E Spooncer, C. P. Daniel
Publikováno v:
Novartis Foundation Symposia ISBN: 9780470513880
Ciba Foundation Symposium 148-Molecular Control of Haemopoiesis
Ciba Foundation Symposium 148-Molecular Control of Haemopoiesis
Stromal cells of the bone marrow can provide the growth-promoting and differentiation-inducing molecules which are necessary for haemopoiesis. While the nature of these stimuli is largely unknown, the development of haemopoietic cells in association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7137d028320bacb8975bdf72b33b8817
https://doi.org/10.1002/9780470513880.ch6
https://doi.org/10.1002/9780470513880.ch6
Autor:
E A, de Wynter, C M, Heyworth, N, Mukaida, E, Jaworska, A, Weffort-Santos, K, Matushima, N G, Testa
Publikováno v:
Journal of leukocyte biology. 70(3)
Simple methods that separate progenitor cells of different hemopoietic lineages would facilitate studies on lineage commitment and differentiation. We used an antibody specific for the chemokine receptor CCR1 to examine mononuclear cells isolated fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2330ea722042b2cd04215d8cb6749b4f
https://pubmed.ncbi.nlm.nih.gov/11527996
https://pubmed.ncbi.nlm.nih.gov/11527996
Autor:
M, Scheller, J, Foerster, C M, Heyworth, J F, Waring, J, Löhler, G L, Gilmore, R K, Shadduck, T M, Dexter, I, Horak
Publikováno v:
Blood. 94(11)
Mice deficient for the transcription factor, interferon consensus sequence binding protein (ICSBP), are immunodeficient and develop disease symptoms similar to human chronic myeloid leukemia (CML). To elucidate the hematopoietic disorder of ICSBP(-/-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6cc68b36ec430461e723ea18d7e6e236
https://pubmed.ncbi.nlm.nih.gov/10572090
https://pubmed.ncbi.nlm.nih.gov/10572090
Autor:
L G, Czaplewski, J, McKeating, C J, Craven, L D, Higgins, V, Appay, A, Brown, T, Dudgeon, L A, Howard, T, Meyers, J, Owen, S R, Palan, P, Tan, G, Wilson, N R, Woods, C M, Heyworth, B I, Lord, D, Brotherton, R, Christison, S, Craig, S, Cribbes, R M, Edwards, S J, Evans, R, Gilbert, P, Morgan, E, Randle, N, Schofield, P G, Varley, J, Fisher, J P, Waltho, M G, Hunter
Publikováno v:
The Journal of biological chemistry. 274(23)
Human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES (regulated on activation normal T cell expressed) self-associate to form high-molecular mass aggregates. To explore the biological significance of chemokine aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::48762b18c9697b7baf7ab60c03d548be
https://pubmed.ncbi.nlm.nih.gov/10347159
https://pubmed.ncbi.nlm.nih.gov/10347159