Zobrazeno 1 - 3
of 3
pro vyhledávání: '"C. M. Cribbs"'
Autor:
S V, Frye, C D, Haffner, P R, Maloney, R A, Mook, G F, Dorsey, R N, Hiner, C M, Cribbs, T N, Wheeler, J A, Ray, R C, Andrews
Publikováno v:
Journal of Medicinal Chemistry. 37:2352-2360
6-Azaandrost-4-en-3-ones were synthesized and tested versus human type 1 and 2 steroid 5 alpha-reductase (5AR) and human adrenal 3 beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase (3BHSD) to explore the structure-activity r
Publikováno v:
ChemInform. 22
Autor:
C M Cribbs, P M Blumberg, Konrad F. Koehler, George R. Pettit, C L Herald, Paul A. Wender, Y Kamano, N A Sharkey
Publikováno v:
Proceedings of the National Academy of Sciences. 85:7197-7201
The bryostatins are macrocyclic lactones that represent an additional structural class of potent activators of protein kinase C. These marine animal biosynthetic products are of unusual interest because they induce only a subset of the biological res