Plasma ESR1 mutations and outcome to first-line paclitaxel and bevacizumab in patients with advanced ER-positive/HER2-negative breast cancer

Autor: M. K. Bos, S. W. Lam, G. Motta, J. C. A. Helmijr, C. M. Beaufort, E. de Jonge, J. W. M. Martens, E. Boven, M. P. H. M. Jansen, A. Jager, S. Sleijfer

Publikováno v: Bos, M K, Lam, S W, Motta, G, Helmijr, J C A, Beaufort, C M, de Jonge, E, Martens, J W M, Boven, E, Jansen, M P H M, Jager, A & Sleijfer, S 2023, ' Plasma ESR1 mutations and outcome to first-line paclitaxel and bevacizumab in patients with advanced ER-positive/HER2-negative breast cancer ', Breast Cancer Research and Treatment, vol. 200, no. 2, pp. 271-279 . https://doi.org/10.1007/s10549-023-06965-5
Breast Cancer Research and Treatment, 200(2), 271-279. Springer New York

Background ESR1 mutations have been identified as mechanism for endocrine resistance and are also associated with a decreased overall survival. We assessed ESR1 mutations in circulating tumor DNA (ctDNA) for impact on outcome to taxane-based chemothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7aebbcd0120eb600dc370a3b31b7216
https://pure.eur.nl/en/publications/00ba171e-1ab7-4e84-bef7-427b3ddafd1e

A large family characterised by nocturnal sudden death

Autor: M P, van den Berg, J W, Viersma, G C M, Beaufort-Krol, M Th E, Bink-Boelkens, C R, Bezzina, M W, Veldkamp, J, Brouwer, J, Haaksma, J P, van Tintelen, I M, van Langen, A A, Wouda, A A M, Wilde

Publikováno v: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation. 10(7-8)

We recently identified a novel mutation in large family characterised by premature nocturnal sudden death. In the present paper we provide an overview of the findings in this family.From 1958 onwards, when the first patient presented, we collected cl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6adeae5ec29a72528fe740a272c9638d
https://pubmed.ncbi.nlm.nih.gov/25696119

Metabolic responses to moderate exercise in lambs with aortopulmonary shunts

Autor: Janny Takens, A.M. Gerding, W. G. Zijlstra, Jaap R. G. Kuipers, Marieke C. Molenkamp, Gertie C. M. Beaufort-Krol

Publikováno v: Metabolism, 50(4), 399-406. W B SAUNDERS CO-ELSEVIER INC

In a previous study we found, after an overnight fast of 18 hours, a lower arterial glucose concentration and a depressed glycogenolysis in lambs with aortopulmonary left-to-right shunts. During exercise, glucose and free fatty acids (FFA) concentrat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abd5e635a2fcbdab5090e5f213c8517
https://doi.org/10.1053/meta.2001.21689

Myocardial Lactate Metabolism in Fetal and Newborn Lambs

Autor: Hennie Knoester, W. G. Zijlstra, Jaap R. G. Kuipers, Beatrijs Bartelds, Janny Takens, Gioia B. Smid, Gertie C. M. Beaufort-Krol, Hugo S. A. Heymans

Publikováno v: Circulation, 99(14), 1892-1897. LIPPINCOTT WILLIAMS & WILKINS

Background —Around birth, myocardial substrate supply changes from carbohydrates before birth to primarily fatty acids after birth. Parallel to these changes, the myocardium is expected to switch from the use of primarily lactate before birth to fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a18cb879a0e086a2bd05094c916bec5
https://doi.org/10.1161/01.cir.99.14.1892

The right auricle tunnel as intercaval tunnel in total cavopulmonary connection may prevent atrial flutter1

Autor: Tjalling W. Waterbolk, Tjark Ebels, Nynke J. Elzenga, Gertie C. M. Beaufort-Krol, Margreet Th.E. Bink-Boelkens

Publikováno v: European Journal of Cardio-Thoracic Surgery. 14:590-595

Objective: Total cavopulmonary connection (TCPC) is a routine operation for palliation of children with cardiac anomalies in whom biventricular repair is impossible. The original technique consists of the creation of a semi-prosthetic intercaval tunn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::700658e2d64f3ff17e63ecd6ccda4761
https://doi.org/10.1016/s1010-7940(98)00254-1