Zobrazeno 1 - 10
of 11
pro vyhledávání: '"C. M. Aderman"'
Autor:
Matthew Campbell, Roberta J. Dennison, Lois E.H. Smith, Aimee M. Juan, Akiko Mammoto, Jing Chen, Karen I. Guerin, C. M. Aderman, Keirnan L. Willett, Nathan M. Krah, Przemyslaw Sapieha, Colman J. Hatton, Jing Hua, Andreas Stahl, Molly R. Seaward
Publikováno v:
Circulation. 124:1871-1881
Background— Ischemic proliferative retinopathy, characterized by pathological retinal neovascularization, is a major cause of blindness in working-age adults and children. Defining the molecular pathways distinguishing pathological neovascularizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beabc6f899237df852b424ccda5f6dc8
https://doi.org/10.1161/circulationaha.111.040337
https://doi.org/10.1161/circulationaha.111.040337
Autor:
Karen I. Guerin, Nathan M. Krah, Przemyslaw Sapieha, Molly R. Seaward, Jing Chen, Roberta J. Dennison, Jing Hua, Lois E.H. Smith, Kip M. Connor, John Paul SanGiovanni, C. M. Aderman, Andreas Stahl, Keirnan L. Willett
Publikováno v:
Circulation Research. 107:495-500
Rationale: Omega3 long-chain polyunsaturated fatty acids (ω3-PUFAs) are powerful modulators of angiogenesis. However, little is known about the mechanisms governing ω3-PUFA–dependent attenuation of angiogenesis. Objective: This study aims to iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad9b22d56b9407eb25a3bed419aee5b
https://doi.org/10.1161/circresaha.110.221317
https://doi.org/10.1161/circresaha.110.221317
Autor:
Nathan M. Krah, Karen I. Guerin, Kip M. Connor, C. M. Aderman, Keirnan L. Willett, Lois E.H. Smith, Andreas Stahl, Roberta J. Dennison, Przemyslaw Sapieha, Jing Chen
Publikováno v:
Nature Protocols. 4:1565-1573
The mouse model of oxygen-induced retinopathy (OIR) has been widely used in studies related to retinopathy of prematurity, proliferative diabetic retinopathy and in studies evaluating the efficacy of antiangiogenic compounds. In this model, 7-d-old (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04c828167bdcd59750db7ba496e3908
https://doi.org/10.1038/nprot.2009.187
https://doi.org/10.1038/nprot.2009.187
Autor:
Alexandra C. H. Smith, Nan Liu, C. M. Aderman, Kip M. Connor, Ann Hellström, Thomas Ludwig, John E. Pintar, Lois E.H. Smith, Chatarina Löfqvist, Jing Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 104:10589-10594
Vessel loss precipitates many diseases. In particular, vessel loss resulting in hypoxia induces retinal neovascularization in diabetic retinopathy and in retinopathy of prematurity (ROP), major causes of blindness. Here we define insulin-like growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a99ce0f09501fed54c2d48340e5e0223
https://doi.org/10.1073/pnas.0702031104
https://doi.org/10.1073/pnas.0702031104
Autor:
Przemyslaw Sapieha, John Paul SanGiovanni, Jing Chen, Emily Y. Chew, Traci E Clemons, Lois E.H. Smith, C. M. Aderman, Andreas Stahl
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53155 (2013)
PLoS ONE
PLoS ONE
Background Increased intake of ω-3 long-chain polyunsaturated fatty acids (LCPUFAs) and use of peroxisome proliferator activator receptor (PPAR)-activating drugs are associated with attenuation of pathologic retinal angiogenesis. ω-3 LCPUFAs are en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6c49fd4b86f57d9f70e8e4db793603
http://europepmc.org/articles/PMC3546058?pdf=render
http://europepmc.org/articles/PMC3546058?pdf=render
Autor:
C. M. Aderman, Andreas Stahl, Molly R. Seaward, Nathan M. Krah, Przemyslaw Sapieha, Aimee M. Juan, Colman J. Hatton, Jean-Sebastian Joyal, Jing Chen, Keirnan L. Willett, Lois E.H. Smith, Roberta J. Dennison
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30203 (2012)
PLoS ONE
PLoS ONE
Mutations in low-density lipoprotein receptor-related protein 5 (Lrp5) impair retinal angiogenesis in patients with familial exudative vitreoretinopathy (FEVR), a rare type of blinding vascular eye disease. The defective retinal vasculature phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601d7470a501946301bd1e8cf137ed57
http://europepmc.org/articles/PMC3260226?pdf=render
http://europepmc.org/articles/PMC3260226?pdf=render
Autor:
Arianna Carughi, Kip M. Connor, C. M. Aderman, Elvira L. Liclican, Roberta J. Dennison, Molly R. Seaward, Yoshihide Kanaoka, Keirnan L. Willett, Lois E.H. Smith, Andreas Stahl, Karsten Gronert, John Paul SanGiovanni, Nathan M. Krah, Dalia Perelman, Przemyslaw Sapieha, Jing Chen
Publikováno v:
Science Translational Medicine. 3
Lipid signaling is dysregulated in many diseases with vascular pathology, including cancer, diabetic retinopathy, retinopathy of prematurity, and age-related macular degeneration. We have previously demonstrated that diets enriched in ω-3 polyunsatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5130a8da603e81c28410cf0019e9c9
https://doi.org/10.1126/scitranslmed.3001571
https://doi.org/10.1126/scitranslmed.3001571
Autor:
Chatarina Löfqvist, C. M. Aderman, Ann Hellström, Emily Y. Chew, Jing X. Kang, Kip M. Connor, Norman Salem, Jing Chen, Deborah Carper, Song Hong, Elke Pravda, Charles N. Serhan, Sharon Majchrzak, Lois E.H. Smith, John Paul SanGiovanni, Akiko Higuchi
Publikováno v:
Nature medicine. 13(7)
Many sight-threatening diseases have two critical phases, vessel loss followed by hypoxia-driven destructive neovascularization. These diseases include retinopathy of prematurity and diabetic retinopathy, leading causes of blindness in childhood and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bc97fe0ee3d6a3d2664ac905dc6cca
https://pubmed.ncbi.nlm.nih.gov/17589522
https://pubmed.ncbi.nlm.nih.gov/17589522
Autor:
Martin Friedlander, C. M. Aderman, Alexandra C. H. Smith, Jeffrey Friedlander, Edith Aguilar, Michael I. Dorrell, Matthew R. Ritter, Eyal Banin
Publikováno v:
Investigative ophthalmologyvisual science. 47(5)
PURPOSE. A carboxyl-terminal fragment of tryptophan tRNA synthetase (T2-TrpRS) has demonstrated potent angiostatic activity during retinal developmental neovascularization in vivo. The effects of T2-TrpRS on pathologic neovascularization were tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d817f9f689146b2d29936fe66adc9c
https://pubmed.ncbi.nlm.nih.gov/16639024
https://pubmed.ncbi.nlm.nih.gov/16639024
Autor:
Keirnan L. Willett, Przemyslaw Sapieha, C. M. Aderman, Roberta J. Dennison, Ann Hellström, Jing Hua, Kip M. Connor, Molly R. Seaward, Chatarina Löfqvist, Jing Chen, Nathan M. Krah, Andreas Stahl, Karen I. Guerin, Lois E.H. Smith
Publikováno v:
Investigative Opthalmology & Visual Science. 51:2813
The mouse retina has been used extensively over the past decades to study both physiologic and pathologic angiogenesis. Over time, various mouse retina models have evolved into well-characterized and robust tools for in vivo angiogenesis research. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274bb587e036da175509d0aeaaa7d7d7
https://doi.org/10.1167/iovs.10-5176
https://doi.org/10.1167/iovs.10-5176