The bacterial cytoskeleton modulates motility, type 3 secretion, and colonization in Salmonella.

Autor: David M Bulmer, Lubna Kharraz, Andrew J Grant, Paul Dean, Fiona J E Morgan, Michail H Karavolos, Anne C Doble, Emma J McGhie, Vassilis Koronakis, Richard A Daniel, Pietro Mastroeni, C M Anjam Khan

Publikováno v: PLoS Pathogens, Vol 8, Iss 1, p e1002500 (2012)

Although there have been great advances in our understanding of the bacterial cytoskeleton, major gaps remain in our knowledge of its importance to virulence. In this study we have explored the contribution of the bacterial cytoskeleton to the abilit

Externí odkaz: https://doaj.org/article/0e54051753e7417a9ab0ff1ecf95a74a

Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop on host communication systems

Autor: Klaus Winzer, Michail H. Karavolos, C. M. Anjam Khan, Paul Williams

Publikováno v: Molecular Microbiology. 87:455-465

The interactions between bacterial pathogens and their eukaryotic hosts are vital in determining the outcome of infections. Bacterial pathogens employ molecular sensors to detect and facilitate adaptation to changes in their niche. The sensing of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a54c2a408c58428b93778642a1bbbb6d
https://doi.org/10.1111/mmi.12110

Interkingdom crosstalk

Autor: Michail H. Karavolos, C. M. Anjam Khan, Paul Williams

Publikováno v: Scopus-Elsevier

The ability of bacterial pathogens to sense their immediate environment plays a significant role on their capacity to survive and cause disease. Salmonella enterica serovar typhi (S. typhi) is an exclusively human pathogen that causes typhoid fever.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddd652be15217d5ff4705f3dc74baae
https://doi.org/10.4161/viru.2.4.16810

The structure and proinflammatory activity of the lipopolysaccharide from Burkholderia multivorans and the differences between clonal strains colonizing pre and posttransplanted lungs

Autor: Heather Brookes, Luisa Sturiale, Teresa Ieranò, Rosa Lanzetta, F. Kate Gould, Paul A. Corris, Antonio Molinaro, Domenico Garozzo, C. M. Anjam Khan, Michelangelo Parrilli, Alba Silipo, Anthony De Soyza, Clare E. Bryant

Publikováno v: Glycobiology (Oxf.) 18 (2008): 871–881.
info:cnr-pdr/source/autori:T.Ieranò, A.Silipo, L.Sturiale, D.Garozzo, H.Brookes, C.M.Anjam Khan, C.Bryant, F.K.Gould, P.A.Corris, R.Lanzetta, M.Parrilli, A.De Soyza, A.Molinaro/titolo:The structure and proinflammatory activity of the lipopolysaccharide from Burkholderia multivorans and the differences between clonal strains colonizing pre and posttransplanted lungs/doi:/rivista:Glycobiology (Oxf.)/anno:2008/pagina_da:871/pagina_a:881/intervallo_pagine:871–881/volume:18

The Burkholderia cepacia complex is a group of Gram-negative bacteria that are opportunistic pathogens for humans especially in cystic fibrosis patients. Lipopolysaccharide (LPS) molecules are potent virulence factors of Gram-negative bacteria organi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c913bccb7f180a64da8a2dc8c2c6aa7
https://doi.org/10.1093/glycob/cwn074

Genetic detoxification of anaroA Salmonella entericaserovar Typhimurium vaccine strain does not compromise protection against virulentSalmonellaand enhances the immune responses towards a protective malarial antigen

Autor: Fidel Zavala, Michail H. Karavolos, C E Hormaeche, Jeong Jin Lee, Duncan J. Maskell, David M. Bulmer, C. M. Anjam Khan, Shahid Khan, Nicola D. McKelvie, Raquel DeMarco

Publikováno v: FEMS Immunology & Medical Microbiology. 52:237-246

Live Salmonella vaccines are limited in use by the inherent toxicity of the lipopolysaccharide. The waaN gene encodes a myristyl transferase required for the secondary acylation of lipid A in lipopolysaccharide. A waaN mutant exhibits reduced inducti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7758d62e187a8a4d677e31c79bc88988
https://doi.org/10.1111/j.1574-695x.2007.00368.x