Effect of Antiangiogenic-Based Treatment and Systemic Inflammatory Factors on Outcomes in Patients With BRAF v600-Mutated Metastatic Colorectal Cancer: A Real-World Study in Spain

Autor: Nieves Martinez Lago, Ana Fernández Montes, Marta Covela Rúa, Elena M. Brozos Vázquez, Juan C. De la Cámara Gómez, Jose C. Méndez Méndez, Mónica Jorge Fernández, Antía Cousillas Castiñeiras, Cristina Reboredo Rendo, David Arias Ron, Marta Carmona Campos, Yolanda Vidal Insua, Maria L. Pellón Augusto, Paula González Villarroel, Begoña Graña Suarez, Mercedes Salgado Fernández, Alberto Carral Maseda, Francisca Vázquez Rivera, Sonia Candamio Folgar, Margarita Reboredo López

Background Outcomes are poorer in metastatic colorectal cancer (mCRC) patients with BRAF V600E mutations than those without it, but the effect of these mutations on treatment response is unclear. This real-world study assessed the effects of antiangi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4516fdfd7ed86ceeb492a6f2d08d1f56
https://doi.org/10.21203/rs.3.rs-79440/v1

PULSE: An open-label, phase II study assessing double positivity (phospho-insulin-growth factor receptor-1 [pIGF-IR] and matrilysin [MMP7]) expression as a predictive marker of resistance in previously untreated metastatic colorectal cancer (mCRC) wild-type KRAS patients (pts) treated with panitumumab plus mFOLFOX6—A GEMCAD study

Autor: Jorge Aparicio, Miriam Cuatrecasas, C. Méndez Méndez, Juan Maurel, Xabier García-Albéniz, Michele Rubini, M. Martin-Richard, Carles Pericay, Ruth Vera

Publikováno v: Journal of Clinical Oncology. 29:TPS164-TPS164

TPS164 Background: By transactivaction, p-IGF-IR can activate epidermal growth factor receptor (EGFR). Matrilysin (MMP-7), can activate IGF-IR by degrading IGFBP-3 and releasing IGF-I. Concomitant expression of MMP-7 and p-IGF-IR (using a specific mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b6e2946fddc0e023de7a1d971e3162d
https://doi.org/10.1200/jco.2011.29.15_suppl.tps164

Reveal the relationship between the quality and the cuticle composition of Satsuma mandarin (Citrus unshiu) by postharvest heat treatment.

Autor: Wu, Sisi, Li, Xiang, Jiang, Jing, Huang, Hua, Cheng, Xiaomei, Li, Gaoyang, Shan, Yang, Zhu, Xiangrong

Publikováno v: Journal of Food Science (John Wiley & Sons, Inc.); Dec2023, Vol. 88 Issue 12, p4879-4891, 13p

Effect of antiangiogenic-based treatment and systemic inflammatory factors on outcomes in patients with BRAF v600-mutated metastatic colorectal cancer: a real-world study in Spain.

Autor: Martínez-Lago, Nieves¹ (AUTHOR) Nieves.Purificacion.Martinez.Lago@sergas.es, Fernández-Montes, Ana² (AUTHOR), Covela, Marta³ (AUTHOR), Brozos, Elena M.⁴ (AUTHOR), De la Cámara, Juan⁵ (AUTHOR), Méndez Méndez, José C.⁶ (AUTHOR), Jorge-Fernández, Mónica⁷ (AUTHOR), Cousillas Castiñeiras, Antía⁸ (AUTHOR), Reboredo, Cristina¹ (AUTHOR), Arias Ron, David² (AUTHOR), Pellón Augusto, María L.⁵ (AUTHOR), González Villarroel, Paula⁷ (AUTHOR), Graña, Begoña¹ (AUTHOR), Salgado Fernández, Mercedes² (AUTHOR), Carral Maseda, Alberto³ (AUTHOR), Vázquez Rivera, Francisca⁴ (AUTHOR), Candamio Folgar, Sonia⁴ (AUTHOR), Reboredo López, Margarita¹ (AUTHOR), Galician Research Group on Digestive Tumors (GITuD) (CORPORATE AUTHOR)

Publikováno v: BMC Cancer. 1/14/2021, Vol. 21 Issue 1, p1-10. 10p.

Advances and challenges in the detection of academic stress and anxiety in the classroom: A literature review and recommendations.

Autor: Jiménez-Mijangos, Laura P., Rodríguez-Arce, Jorge, Martínez-Méndez, Rigoberto, Reyes-Lagos, José Javier

Publikováno v: Education & Information Technologies; Apr2023, Vol. 28 Issue 4, p3637-3666, 30p