Zobrazeno 1 - 10
of 11
pro vyhledávání: '"C. Lorrie Epling"'
Autor:
Steven G. DuBois, Crystal L. Mackall, Stephen L. Lessnick, Richard G. Gorlick, Richard B. Womer, Katherine K. Matthay, Donald A. Barkauskas, Mark D. Krailo, Elizabeth McIlvaine, Phillip Barnette, Katherine A. Janeway, Holcombe E. Grier, Douglas S. Hawkins, Elizabeth Sinclair, C. Lorrie Epling, Jeremy V. Edwards, Kieuhoa T. Vo
Supplemental Table 1. Association of clinical features with BM micrometastatic cell burden (CD99+CD45- percent) in flow cytometry cohort. Supplemental Table 2. Total CD99+CD45- percent burden in Ewing sarcoma patients with clinically evident BM metas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231c81b01ab283631b8f4ce8da780d85
https://doi.org/10.1158/1078-0432.22457171
https://doi.org/10.1158/1078-0432.22457171
Autor:
Steven G. DuBois, Crystal L. Mackall, Stephen L. Lessnick, Richard G. Gorlick, Richard B. Womer, Katherine K. Matthay, Donald A. Barkauskas, Mark D. Krailo, Elizabeth McIlvaine, Phillip Barnette, Katherine A. Janeway, Holcombe E. Grier, Douglas S. Hawkins, Elizabeth Sinclair, C. Lorrie Epling, Jeremy V. Edwards, Kieuhoa T. Vo
Purpose: Flow cytometry and RT-PCR can detect occult Ewing sarcoma cells in the blood and bone marrow. These techniques were used to evaluate the prognostic significance of micrometastatic disease in Ewing sarcoma.Experimental Design: Newly diagnosed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64770d357efe2df1e42c36dc5754ae65
https://doi.org/10.1158/1078-0432.c.6523523
https://doi.org/10.1158/1078-0432.c.6523523
Autor:
Katherine K. Matthay, Crystal L. Mackall, Phillip Barnette, Richard B. Womer, Steven G. DuBois, Douglas S. Hawkins, Elizabeth Sinclair, Stephen L. Lessnick, Richard Gorlick, Katherine A. Janeway, Jeremy V. Edwards, Donald A. Barkauskas, Kieuhoa T. Vo, Holcombe E. Grier, C. Lorrie Epling, Mark Krailo, Elizabeth McIlvaine
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 22, iss 14
Purpose: Flow cytometry and RT-PCR can detect occult Ewing sarcoma cells in the blood and bone marrow. These techniques were used to evaluate the prognostic significance of micrometastatic disease in Ewing sarcoma. Experimental Design: Newly diagnose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fc08cb61a8c1bf87bd85c88ca5b61a
https://doi.org/10.1158/1078-0432.ccr-15-2516
https://doi.org/10.1158/1078-0432.ccr-15-2516
Autor:
Jeffery N Martin, Qi Xuan Tan, Rachel E. Owen, Frederick Hecht, Jeffery M. Harris, Mark A. Jacobson, John W. Heitman, Joseph M. McCune, Dale F. Hirschkorn, Brian Custer, Philip J. Norris, Elizabeth Sinclair, Steven G. Deeks, C. Lorrie Epling, Brinda Emu
Publikováno v:
Journal of Immunological Methods. 326:93-115
Although cryopreservation of peripheral blood mononuclear cells (PBMC) is a commonly used technique, the degree to which it affects subsequent functional studies has not been well defined. Here we demonstrate that long-term cryopreservation has detri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d6f26d857f67e87785526618574a4d
https://doi.org/10.1016/j.jim.2007.07.012
https://doi.org/10.1016/j.jim.2007.07.012
Autor:
Terence Ho, Alexander Carvidi, Raji Bains, Laurie Agrillo, Mark A. Jacobson, Stuart P. Adler, Elizabeth Sinclair, C. Lorrie Epling, Douglas Black, Barry M. Bredt
Publikováno v:
Journal of Clinical Virology. 35:332-337
Background Towne cytomegalovirus (CMV) vaccine is safe and immunogenic, though its protective efficacy has yet to be optimized. Objective Describe antigen-specific T cell responses to Towne vaccination. Study design 3000 pfu Towne CMV vaccine were gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a818223575eedbf6ddf9f1bad9ee8b5
https://doi.org/10.1016/j.jcv.2005.09.019
https://doi.org/10.1016/j.jcv.2005.09.019
Autor:
Alexander Carvidi, Douglas Black, Elizabeth Sinclair, Steven Z. Josefowicz, C. Lorrie Epling, Barry M. Bredt, Mark A. Jacobson
Publikováno v:
Viral Immunology. 17:445-454
CMV-specific CD4+ and CD8+ T cell IFNγ expression and proliferation were measured in healthy volunteers by flow cytometry after CMV lysate or CMV pp65 or IE peptide pool stimulation. Cutoff values were set to maximize specificity (i.e., no false pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28402c8da27d52ba435a47c1da46c496
https://doi.org/10.1089/vim.2004.17.445
https://doi.org/10.1089/vim.2004.17.445
A new method for detecting circulating Ewing sarcoma cells using flow cytometry is described. This strategy exploits the nearly universal expression of CD99 and the lack of expression of CD45 by Ewing sarcoma cells.Ewing sarcoma cell line A673, perip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a56b205693060558911cb291694d3e4b
https://europepmc.org/articles/PMC2846759/
https://europepmc.org/articles/PMC2846759/
Autor:
Laurie Agrillo, Barry M. Bredt, Mark A. Jacobson, Stuart P. Adler, Terence Ho, Elizabeth Sinclair, C. Lorrie Epling, Douglas Black, Raji Bains, Valerie Girling, Alexander Carvidi
Publikováno v:
Vaccine. 24(25)
The Towne, human cytomegalovirus (CMV) vaccine is safe and immunogenic but has not prevented infection at doses tested to date. We administered 3000 pfu Towne CMV vaccine, with or without adjuvant recombinant interleukin-12 (rhIL-12), to CMV-seronega
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68e1e830eb4a391d2b5bdf0868723d2
https://pubmed.ncbi.nlm.nih.gov/16701925
https://pubmed.ncbi.nlm.nih.gov/16701925
Publikováno v:
Journal of Clinical Oncology. 30:23-23
23 Background: Targeting the IGF-1R pathway has shown preclinical and clinical evidence of activity in EWS. Markers predictive of response to IGF-1R inhibition are required. The aims of the current study were to quantify surface IGF-1R expression and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b1e08d1cafa64e5759c9eedcf69ae2e
https://doi.org/10.1200/jco.2012.30.30_suppl.23
https://doi.org/10.1200/jco.2012.30.30_suppl.23
Autor:
Timothy W. Tobery, Barry M. Bredt, Ruth Baydo, Omu Anzala, Rafick Pierre Sekaly, Gailet Alter, Janice Darden, Giuseppe Pantaleo, Alexandre Harari, Nolwenn Nougarede, Sandra A. Calarota, Peter Hayes, Eva Roig, Claire Landry, Miguel Garcia, Aline Rinfret, Maria A. Suni, Mario Roederer, Jennifer Holbrook, Janet Ottinger, Laurie Lamoreaux, Hazel Maila, Clive M. Gray, Jill Gilmour, Lynda G. Tussey, Patricia D'Souza, Elizabeth Sinclair, Sophia El-Bahi, Josephine Birungi, Ian Frank, Marcus Altfeld, Vernon C. Maino, Kara Punt, Josephine H. Cox, Helen Horton, Megan Baker, C. Lorrie Epling, Richard A. Koup, Holden T. Maecker, Jean D. Boyer, Ellen G. Kuta, Kent J. Weinhold
Publikováno v:
BMC Immunology. 6:13
Cytokine flow cytometry (CFC) or intracellular cytokine staining (ICS) can quantitate antigen-specific T cell responses in settings such as experimental vaccination. Standardization of ICS among laboratories performing vaccine studies would provide a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d933612f02f6190efb917416f48b463
https://doi.org/10.1186/1471-2172-6-13
https://doi.org/10.1186/1471-2172-6-13