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Akademický článek

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Brief heat shock treatment induces a long-lasting alteration in the glycolipid receptor binding specificity and growth rate of Haemophilus influenzae

Autor: E Hartmann, C Lingwood

Publikováno v: Infection and Immunity. 65:1729-1733

After brief heat shock treatment, clinical strains of nontypeable Haemophilus influenzae show a long-lasting change in the binding specificity for glycolipids and a markedly increased growth rate in vitro. Non-heat-shocked H. influenzae specifically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb85628c4255f2421d421254436dd90
https://doi.org/10.1128/iai.65.5.1729-1733.1997

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Escherichia coli verotoxin binding to human paediatric glomerular mesangial cells

Autor: L. A. Robinson, R. M. Hurley, Douglas G. Matsell, C. Lingwood

Publikováno v: Pediatric Nephrology. 9:700-704

Haemolytic uraemic syndrome (HUS) remains the leading cause of acute renal failure in children. Although an Escherichia coli-produced verotoxin (VT) has been implicated in the pathogenesis of HUS, the precise mechanisms of disease are not well define

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a32c892c90ca08c1b5cb84bc0f8ba3b
https://doi.org/10.1007/bf00868715

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Modification of the glycolipid-binding specificity of vero cytotoxin by polymyxin B and other cyclic amphipathic peptides

Autor: S Head, K Ramotar, C Lingwood

Publikováno v: Infection and Immunity. 58:1532-1537

Polymyxin B, an amphipathic cyclic decapeptide produced by Bacillus polymyxa, is routinely used in the extraction of the components from the periplasmic space of gram-negative bacteria. Vero cytotoxin 1 (VT1) is an Escherichia coli-elaborated subunit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752dfd2c6727e7f3da27be644e52a3e7
https://doi.org/10.1128/iai.58.6.1532-1537.1990

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MHC class II proteins contain a potential binding site for the verotoxin receptor glycolipid CD77

Autor: T, George, B, Boyd, M, Price, C, Lingwood, M, Maloney

Publikováno v: Cellular and molecular biology (Noisy-le-Grand, France). 47(7)

Globotriaosyl ceramide or CD77 functions as a cell surface receptor for toxins of the Shiga toxin/verotoxin family and as a marker for germinal center stage B-cells. The B-cell protein CD19 and the interferon-alpha receptor possess verotoxin-like ami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7830fada0a9ec99614524c14c4033820
https://pubmed.ncbi.nlm.nih.gov/11838965

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Kniha

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Verotoxin induces apoptosis and the complete, rapid, long-term elimination of human astrocytoma xenografts in nude mice

Autor: S, Arab, J, Rutka, C, Lingwood

Publikováno v: Oncology research. 11(1)

Verotoxin 1 (VT1) is an E. coli elaborated subunit toxin active only against (tumor) cell lines that express the VT1 receptor, globotriaosyl ceramide-Gb3. Astrocytomas can be highly malignant brain tumors that remain refractory to clinical treatment.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e5b9462a0f72934ef65888dfc6e61e20
https://pubmed.ncbi.nlm.nih.gov/10451029

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Expression and sulfogalactolipid binding specificity of the recombinant testis-specific cognate heat shock protein 70

Autor: D, Mamelak, C, Lingwood

Publikováno v: Glycoconjugate journal. 14(6)

Immunofluorescent studies with anti-2A antisera, raised specifically against a synthetic C-terminal peptide of native murine P70, the testes-specific cognate heat shock protein 70, demonstrated that the rat homologue of P70 is expressed on the surfac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba23b2029c3f0abf9ae5dffe531617bf
https://pubmed.ncbi.nlm.nih.gov/9337084

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Akademický článek

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Deficiency in the regulation of testicular galactolipid sulphotransferase in rats carrying the growth-and-reproduction-complex (grc) gene

Autor: H W Kunz, C Lingwood, T J Gill

Publikováno v: Biochemical Journal. 231:401-405

The regulation of the activity of testicular germ-cell galactolipid sulphotransferase was investigated in rats homozygous for the grc (growth and reproductive complex) gene. In the adult grc homozygotes, the activity was elevated relative to that in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90aa231e035aef8f446f344130ebab56
https://doi.org/10.1042/bj2310401

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