Zobrazeno 1 - 6
of 6
pro vyhledávání: '"C. Lance Carlson"'
Autor:
C. Lance Carlson, Gerard F. Graminski, Josh R. Ziemer, Mark R. Burns, Nicolaas M.J. Vermeulen, Feng Cai, Scott M. Vanderwerf
Publikováno v:
Bioorganic and Medicinal Chemistry Letters, 12(1), 35-40. Elsevier Limited
Graminski, G F, Carlson, C, Ziemer, J R, Cai, F, Vermeulen, N P E, Vanderwerf, S M & Burns, M R 2002, ' Synthesis of bis-spermine dimers that are potent polyamine transport inhibitors ', Bioorganic and Medicinal Chemistry Letters, vol. 12, no. 1, pp. 35-40 . https://doi.org/10.1016/S0960-894X(01)00659-X
Graminski, G F, Carlson, C, Ziemer, J R, Cai, F, Vermeulen, N P E, Vanderwerf, S M & Burns, M R 2002, ' Synthesis of bis-spermine dimers that are potent polyamine transport inhibitors ', Bioorganic and Medicinal Chemistry Letters, vol. 12, no. 1, pp. 35-40 . https://doi.org/10.1016/S0960-894X(01)00659-X
A series of novel spermine dimer analogues was synthesized and assessed for their ability to inhibit spermidine transport into MDA-MB-231 breast carcinoma cells. Two spermine molecules were tethered via their N(1) primary amines with naphthalenedisul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b8fe19e236c6e62a7487d0ee7427b8
https://doi.org/10.1016/s0960-894x(01)00659-x
https://doi.org/10.1016/s0960-894x(01)00659-x
Autor:
Reitha S. Weeks, Michael T. Howard, Raymond F. Gesteland, Jiadong Zhou, C. Lance Carlson, John F. Atkins, Senya Matsufuji, Brian H. Shirts
Publikováno v:
Genes to Cells. 6:931-941
Background Antizyme is a critical regulator of cellular polyamine levels due to its effect on polyamine transport and its ability to target ornithine decarboxylase for degradation. Antizyme expression is autoregulatory, through dependence on an unusu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f48d138f4883c1fe8399fdb73920d24
https://doi.org/10.1046/j.1365-2443.2001.00477.x
https://doi.org/10.1046/j.1365-2443.2001.00477.x
Autor:
Gerard F. Graminski, C. Lance Carlson, Reitha S. Weeks, Josh R. Ziemer, Scott M. Vanderwerf, Mark R. Burns, Heather K. Webb, Feng Cai
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4985b058f19b0e271e49fd48b8f643f
https://doi.org/10.1002/chin.200208075
https://doi.org/10.1002/chin.200208075
Autor:
Gerard F. Graminski, Solveig LaTurner, Maralee Mcvean, Josh R. Ziemer, Scott M. Vanderwerf, Mark R. Burns, Jay R. Carreon, Bruce H. Devens, Reitha S. Weeks, C. Lance Carlson
Publikováno v:
Bioorganicmedicinal chemistry letters. 12(9)
A series of aromatic substituted diamines was synthesized and characterized for their cytotoxic profiles against human breast and prostate tumor cell lines. Following a structure function analysis of the effects of changes of the benzyl substituents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c558264e9610899e12d2c9f51b951cc8
https://pubmed.ncbi.nlm.nih.gov/11965367
https://pubmed.ncbi.nlm.nih.gov/11965367
Autor:
Scott M. Vanderwerf, Feng Cai, Gerard F. Graminski, and Heather K. Webb, C. Lance Carlson, Reitha S. Weeks, Josh R. Ziemer, Mark R. Burns
Publikováno v:
Journal of medicinal chemistry. 44(22)
In this paper we describe the synthesis and characterization of a series of simple spermine/amino acid conjugates, some of which potently inhibit the uptake of spermidine into MDA-MB-231 breast cancer cells. The presence of an amide in the functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44641262c4ff1288e59c1709d4d88acb
https://pubmed.ncbi.nlm.nih.gov/11606128
https://pubmed.ncbi.nlm.nih.gov/11606128
Autor:
Scott M. Vanderwerf, Mark R. Burns, Heather K. Webb, Reitha S. Weeks, Bruce H. Devens, C. Lance Carlson, Christine L O'day, Feng Cai
Publikováno v:
Experimental cell research. 261(1)
Polyamines are ubiquitous molecules with multiple intracellular functions. Cells tightly regulate their levels through feedback mechanisms affecting synthesis, intracellular conversion, and transport. Because polyamines have an important role in regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04fc93fd9ad26dc825f334ff414063b6
https://pubmed.ncbi.nlm.nih.gov/11082299
https://pubmed.ncbi.nlm.nih.gov/11082299