Zobrazeno 1 - 10
of 414
pro vyhledávání: '"C. LaBranche"'
Autor:
J.M. Sung, J. Pickeral, M. Bednar, L. Liu, S.A. Stanfield-Oakley, J. Pollara, C. LaBranche, M.A. Moody, M. Bonsignori, C.Y. Kao Lam, S. Johnson, C. Garrido, N. Archin, J. Kuruc, M. Cohen, K. Soderberg, H.X. Liao, D. Montefiori, R. Swanstrom, S. Koenig, J. Nordstrom, B.F. Haynes, G. Ferrari, D. Margolis
Publikováno v:
Journal of Virus Eradication, Vol 1, Iss , Pp 18- (2015)
Externí odkaz:
https://doaj.org/article/34380fb6cc55489f887c45a33bd32d2e
Autor:
Venkata S. Bollimpelli, Pradeep B. J Reddy, Sailaja Gangadhara, Tysheena P. Charles, Samantha L. Burton, Gregory K. Tharp, Tiffany M. Styles, Celia C. Labranche, Justin C. Smith, Amit A. Upadhyay, Anusmita Sahoo, Traci Legere, Ayalnesh Shiferaw, Vijayakumar Velu, Tianwei Yu, Mark Tomai, John Vasilakos, Sudhir P. Kasturi, George M. Shaw, David Montefiori, Steven E. Bosinger, Pamela A. Kozlowski, Bali Pulendran, Cynthia A. Derdeyn, Eric Hunter, Rama R. Amara
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2
Externí odkaz:
https://doaj.org/article/101d7faa095245b791894f88734b70d5
Autor:
Jelle van Schooten, Elinaz Farokhi, Anna Schorcht, Tom L. G. M. van den Kerkhof, Hongmei Gao, Patricia van der Woude, Judith A. Burger, Tim G. Rijkhold Meesters, Tom Bijl, Riham Ghalaiyini, Hannah L. Turner, Jessica Dorning, Barbera D. C. van Schaik, Antoine H. C. van Kampen, Celia C. Labranche, Robyn L. Stanfield, Devin Sok, David C. Montefiori, Dennis R. Burton, Michael S. Seaman, Gabriel Ozorowski, Ian A. Wilson, Rogier W. Sanders, Andrew B. Ward, Marit J. van Gils
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
HIV-1 vaccine design aims to induce broadly neutralizing antibodies such as IOMA, the only described antibody in its class. Here, the authors present the isolation, characterisation and structure of three additional antibodies within the IOMA class
Externí odkaz:
https://doaj.org/article/00bf4f4cc60648ceb42fb07282abd785
Autor:
Silvia Capucci, Edmund G Wee, Torben Schiffner, Celia C LaBranche, Nicola Borthwick, Albert Cupo, Jonathan Dodd, Hansi Dean, Quentin Sattentau, David Montefiori, Per J Klasse, Rogier W Sanders, John P Moore, Tomáš Hanke
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0293148 (2023)
[This corrects the article DOI: 10.1371/journal.pone.0181886.].
Externí odkaz:
https://doaj.org/article/9afb22a50abb493ea347796b71174785
Autor:
Jelle van Schooten, Anna Schorcht, Elinaz Farokhi, Jeffrey C Umotoy, Hongmei Gao, Tom L G M van den Kerkhof, Jessica Dorning, Tim G Rijkhold Meesters, Patricia van der Woude, Judith A Burger, Tom Bijl, Riham Ghalaiyini, Alba Torrents de la Peña, Hannah L Turner, Celia C Labranche, Robyn L Stanfield, Devin Sok, Hanneke Schuitemaker, David C Montefiori, Dennis R Burton, Gabriel Ozorowski, Michael S Seaman, Ian A Wilson, Rogier W Sanders, Andrew B Ward, Marit J van Gils
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010945 (2022)
Broadly neutralizing antibodies (bNAbs) have remarkable breadth and potency against most HIV-1 subtypes and are able to prevent HIV-1 infection in animal models. However, bNAbs are extremely difficult to induce by vaccination. Defining the developmen
Externí odkaz:
https://doaj.org/article/9a8650aeeb2e4e9db4484031f5c06256
Autor:
Maria L. Knudsen, Parul Agrawal, Anna MacCamy, K. Rachael Parks, Matthew D. Gray, Brittany N. Takushi, Arineh Khechaduri, Kelsey R. Salladay, Rhea N. Coler, Celia C. LaBranche, David Montefiori, Leonidas Stamatatos
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105473- (2022)
Summary: Once naive B cells expressing germline VRC01-class B cell receptors become activated by germline-targeting immunogens, they enter germinal centers and undergo affinity maturation. Booster immunizations with heterologous Envs are required for
Externí odkaz:
https://doaj.org/article/2a64a437ba714d9bb9830002de24fd76
Autor:
Scott P Lawrence, Samra E Elser, Workineh Torben, Robert V Blair, Bapi Pahar, Pyone P Aye, Faith Schiro, Dawn Szeltner, Lara A Doyle-Meyers, Beth S Haggarty, Andrea P O Jordan, Josephine Romano, George J Leslie, Xavier Alvarez, David H O'Connor, Roger W Wiseman, Christine M Fennessey, Yuan Li, Michael Piatak, Jeffrey D Lifson, Celia C LaBranche, Andrew A Lackner, Brandon F Keele, Nicholas J Maness, Mark Marsh, James A Hoxie
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010507 (2022)
The HIV/SIV envelope glycoprotein (Env) cytoplasmic domain contains a highly conserved Tyr-based trafficking signal that mediates both clathrin-dependent endocytosis and polarized sorting. Despite extensive analysis, the role of these functions in vi
Externí odkaz:
https://doaj.org/article/d548a853acc4469fa6a4e1326a82b9a7
Autor:
Jelle van Schooten, Marlies M van Haaren, Hui Li, Laura E McCoy, Colin Havenar-Daughton, Christopher A Cottrell, Judith A Burger, Patricia van der Woude, Leanne C Helgers, Ilhan Tomris, Celia C Labranche, David C Montefiori, Andrew B Ward, Dennis R Burton, John P Moore, Rogier W Sanders, Shane Crotty, George M Shaw, Marit J van Gils
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009736 (2021)
The development of an effective human immunodeficiency virus (HIV-1) vaccine is a high global health priority. Soluble native-like HIV-1 envelope glycoprotein trimers (Env), including those based on the SOSIP design, have shown promise as vaccine can
Externí odkaz:
https://doaj.org/article/174a04f5de89452fb76d485c54ad2f16
Autor:
Norbert Pardi, Celia C. LaBranche, Guido Ferrari, Derek W. Cain, István Tombácz, Robert J. Parks, Hiromi Muramatsu, Barbara L. Mui, Ying K. Tam, Katalin Karikó, Patricia Polacino, Christopher J. Barbosa, Thomas D. Madden, Michael J. Hope, Barton F. Haynes, David C. Montefiori, Shiu-Lok Hu, Drew Weissman
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 15, Iss , Pp 36-47 (2019)
Despite the enormous effort in the development of effective vaccines against HIV-1, no vaccine candidate has elicited broadly neutralizing antibodies in humans. Thus, generation of more effective anti-HIV vaccines is critically needed. Here we charac
Externí odkaz:
https://doaj.org/article/f644ebace38a4334aa9e82c78e280dff
Autor:
Seth H. Pincus, Ryan B. Craig, Lauren Weachter, Celia C. LaBranche, Rafiq Nabi, Connie Watt, Mark Raymond, Tami Peters, Kejing Song, Grace A. Maresh, David C. Montefiori, Pamela A. Kozlowski
Publikováno v:
Vaccines, Vol 9, Iss 7, p 774 (2021)
We have constructed bispecific immunoglobulin-like immunoadhesins that bind to both the HIV-envelope glycoproteins: gp120 and gp41. These immunoadhesins have N terminal domains of human CD4 engrafted onto the N-terminus of the heavy chain of human an
Externí odkaz:
https://doaj.org/article/77d70e8124ea44c6b96175e775d1650e