Zobrazeno 1 - 10
of 11
pro vyhledávání: '"C. L. Zielke"'
Publikováno v:
Journal of Neural Transmission. 110:1-14
In the rodent brain, astrocytes are known to be the primary source of kynurenate (KYNA), an endogenous antagonist of both the glycine(B) and the alpha7 nicotinic acetylcholine receptor. In the present study, primary human astrocytes were used to exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbcc8f8a28b4d6062ef578f6a276308
https://doi.org/10.1007/s00702-002-0770-z
https://doi.org/10.1007/s00702-002-0770-z
Publikováno v:
Developmental Neuroscience. 18:420-425
alpha-Ketoisocaproate was infused into the brain of free-moving, awake rats by microdialysis to create a microenvironment similar to that found in maple syrup urine disease. The eluate of the probe was analyzed for amino acids to determine if alpha-k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fba72f39a84f898a150c9ec3b4185b9
https://doi.org/10.1159/000111436
https://doi.org/10.1159/000111436
Publikováno v:
Journal of neuroscience research. 60(5)
Hydrolysis of extracellular glutamine as a potential source of increased extracellular glutamate in the quinolinic acid (QUIN)-injured brain of the unanesthetized, free-moving rat was examined by microdialysis and HPLC analysis. Injury was initiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c51bcdaba64fb80263b356a28ff4aa7
https://pubmed.ncbi.nlm.nih.gov/10820434
https://pubmed.ncbi.nlm.nih.gov/10820434
Publikováno v:
Neurochemical research. 22(9)
Leucine and alpha-ketoisocaproate (alpha-KIC) were perfused at increasing concentrations into rat brain hippocampus by microdialysis to mimic the conditions of maple syrup urine disease. The effects of elevated leucine or alpha-KIC on the oxidation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20b0a709594ef45d4409adb5dfcdc812
https://pubmed.ncbi.nlm.nih.gov/9251107
https://pubmed.ncbi.nlm.nih.gov/9251107
Publikováno v:
Developmental neuroscience. 15(3-5)
Cultured brain cells oxidize glucose and numerous alternate substrates to CO2 for energy production, however, the importance of these observations to the intact brain have not been established. We have adapted in vivo brain microdialysis procedures t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aab8f1c2bb07f110850d8c3910bb9866
https://pubmed.ncbi.nlm.nih.gov/7805575
https://pubmed.ncbi.nlm.nih.gov/7805575
Publikováno v:
Federation proceedings. 43(1)
Cultured mammalian cells have two primary mechanisms for obtaining energy necessary for growth: carbohydrate metabolism to lactate and glutamine oxidation to CO2. In tissue culture medium containing both glucose and glutamine, the contribution of glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fffeb52c9d2b03c0843feab219e72688
https://pubmed.ncbi.nlm.nih.gov/6690331
https://pubmed.ncbi.nlm.nih.gov/6690331
Publikováno v:
Glutamine Metabolism in Mammalian Tissues ISBN: 9783642697562
Cultured mammalian cells are grown in medium containing carbohydrates, amino acids, salts, vitamins, and growth factors. In the 1950’s Eagle [1] identified the basic composition of tissue culture medium, except for the growth factors which were pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70e5cddcc7aeb84642e2bcd6668641bc
https://doi.org/10.1007/978-3-642-69754-8_16
https://doi.org/10.1007/978-3-642-69754-8_16
Autor:
C L, Zielke, H R, Zielke
Publikováno v:
Biochemical pharmacology. 36(15)
Upregulation of brain adenosine receptors in DBA/2J mice as affected by theophylline and caffeine, adenosine antagonists, was examined following subcutaneous drug implantation to ensure chronic exposure. Scatchard analysis of binding to membranes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fba07c3e3ffab67f7d911e4d2596690d
https://pubmed.ncbi.nlm.nih.gov/3606653
https://pubmed.ncbi.nlm.nih.gov/3606653
Publikováno v:
The Journal of biological chemistry. 246(23)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::da003ed196ca5b05112e19ea1a5b4f59
https://pubmed.ncbi.nlm.nih.gov/5166751
https://pubmed.ncbi.nlm.nih.gov/5166751
Autor:
C L, Zielke, C H, Suelter
Publikováno v:
The Journal of biological chemistry. 246(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba502c1c4e652d43daa6f90b0a970a2d
https://pubmed.ncbi.nlm.nih.gov/4995384
https://pubmed.ncbi.nlm.nih.gov/4995384