Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas

Autor: M, Goggins, M, Schutte, J, Lu, C A, Moskaluk, C L, Weinstein, G M, Petersen, C J, Yeo, C E, Jackson, H T, Lynch, R H, Hruban, S E, Kern

Publikováno v: Cancer research. 56(23)

Germline mutations in BRCA2 predispose carriers to the development of breast, ovarian, and a variety of other cancers. The original localization of the BRCA2 gene was aided by its homozygous deletion in a pancreatic carcinoma; indeed, an excess of pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91fb96ee25d561b64d9bd2a84687cb61
https://pubmed.ncbi.nlm.nih.gov/8968085

Homozygous deletion map at 18q21.1 in pancreatic cancer

Autor: S A, Hahn, A T, Hoque, C A, Moskaluk, L T, da Costa, M, Schutte, E, Rozenblum, A B, Seymour, C L, Weinstein, C J, Yeo, R H, Hruban, S E, Kern

Publikováno v: Cancer research. 56(3)

Absolute genetic differences between neoplastic and nonneoplastic cells can be discerned at sites of homozygous deletions. These deletions are of critical interest because they might be useful in the identification of defective biochemical pathways i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ea254300dc688dbe1171dbac786bcbd
https://pubmed.ncbi.nlm.nih.gov/8564959

Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region

Autor: Mieke Schutte, J.M. Trent, Ester Rozenblum, Hoque At, L T da Costa, M. Bittner, C. L. Weinstein, Christopher A. Moskaluk, Stephan A. Hahn, Paul S. Meltzer

Homozygous deletions have been central to the discovery of several tumor-suppressor genes, but their finding has often been either serendipitous or the result of a directed search. A recently described technique [Lisitsyn, N., Lisitsyn, N. & Wigler,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f64224a3af0aa0e600f884283739ce91
https://europepmc.org/articles/PMC41619/

Fano resonance in one-dimensional quasiperiodic topological phononic crystals towards a stable and high-performance sensing tool.

Autor: Almawgani AHM; Electrical Engineering Department, College of Engineering, Najran University, 11001, Najran, Saudi Arabia., Makhlouf Fathy H; Physics Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62512, Egypt., E Alfassam H; Department of Biology, College of Science, Princess Nourah Bint Abdulrahman University, P.O. BOX 84428, 11671, Riyadh, Saudi Arabia., M El-Sherbeeny A; Industrial Engineering Department, College of Engineering, King Saud University, P.O. Box 800, 11421, Riyadh, Saudi Arabia., Hajjiah A; Department of Electrical Engineering, College of Engineering and Petroleum, Kuwait University, Kuwait City, Kuwait., A Elsayed H; Physics Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62512, Egypt.; Department of Physics, College of Science, University of Ha'il, Ha'il P.O. Box 2440, Hail, Saudi Arabia., R Abukhadra M; Materials Technologies and Their Applications Lab, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt., Al Zoubi W; Materials Electrochemistry Laboratory, School of Materials Science and Engineering, Yeungnam University, Gyeongsan, 38541, Republic of Korea., Semeda R; Physics Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62512, Egypt., Ismail Fathy M; Physics Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62512, Egypt., A H Al-Athwary A; College of Languages and Translation, Najran University, Najran, Saudi Arabia., Mehaney A; Physics Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62512, Egypt. ahmed011236@science.bsu.edu.eg.

Publikováno v: Scientific reports [Sci Rep] 2024 May 27; Vol. 14 (1), pp. 12067. Date of Electronic Publication: 2024 May 27.

Multiple forms of rat liver cysteinesulfinate decarboxylase

Autor: O W Griffith, C L Weinstein

Publikováno v: Journal of Biological Chemistry. 262:7254-7263

Cysteinesulfinate decarboxylase, purified from male rat livers and homogeneous by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, is resolved into five distinct enzyme species (isoforms) by gel isoelectric focusing. Since the isoforms are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::738ecb95832b457deae1c5c7697dbeb3
https://doi.org/10.1016/s0021-9258(18)48231-2