Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5

Autor: C. Becherucci, M. Perretti, E. Solito, C. L. Galeotti, L. Parente

Publikováno v: Mediators of Inflammation, Vol 2, Iss 2, Pp 109-113 (1993)

Human recombinant lipocortins (LCT) 1 and 5 have been expressed in a yeast secretion vector and purified by ion exchange chromatography. The action of the proteins has been investigated in two models of experimental acute inflammation in the rat: car

Externí odkaz: https://doaj.org/article/36263cd8e75942c59ca82c1621cd7fcd

New insights into the molecular basis of progressive myoclonus epilepsy: a multiprotein complex with cystatin B

Autor: Davide Ambrosetti, Marialuisa Melli, Rossella Di Giaimo, C. L. Galeotti, Massimo Riccio, Spartaco Santi

Publikováno v: Scopus-Elsevier
Human molecular genetics
11 (2002): 2941–2950.
info:cnr-pdr/source/autori:Di Giaimo R.1, Riccio M.2, Santi S.2, Galeotti C.3, Ambrosetti D.C.1, Melli M.1/titolo:New insights into the molecular basis of progressive myoclonus epilepsy: a multiprotein complex with cystatin B/doi:/rivista:Human molecular genetics (Print)/anno:2002/pagina_da:2941/pagina_a:2950/intervallo_pagine:2941–2950/volume:11

Cystatin B is an anti-proteolytic polypeptide implicated in progressive myoclonus epilepsy (EPM1), a degenerative disease of the central nervous system. The knock-out mouse model of the disease shows apoptosis of the cerebellar granule cells. We have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0fe5c75262f79b9857ea15daeb964ed
https://hdl.handle.net/11380/797713

Mechanisms of IL-1 different biological activities. Studies using IL-1 muteins and IL-1 receptor antibodies

Autor: P. Ghiara, Egle Solito, K.G. Mugridge, Luca Parente, M. Melli, C. L. Galeotti

Publikováno v: Pharmacological Research. 26:125

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::97bd2d398ad9ec8a9bc85387f3a34659
https://doi.org/10.1016/1043-6618(92)90961-a

A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1 beta in Saccharomyces cerevisiae

Autor: James A. H. Murray, C. L. Galeotti, Cosima T. Baldari, P. Ghiara, Gianni Cesareni

Publikováno v: Scopus-Elsevier

Killer strains of Kluyveromyces lactis secrete a toxin which presumably is processed during secretion from a larger precursor. Analysis of the sequence of the K. lactis killer toxin gene predicts that the first 16 amino acids at the amino terminus of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab49b243839c15f1ae25c272f8af25c3
http://www.scopus.com/inward/record.url?eid=2-s2.0-0023061489&partnerID=MN8TOARS